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CG7409 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 38870, updated on 2-Nov-2024

Summary

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Official Symbol
CG7409provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0035817
Locus tag
Dmel_CG7409
See related
AllianceGenome:FB:FBgn0035817
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CT16169; Dmel46.9; Dmel\CG7409
Summary
Predicted to enable unfolded protein binding activity. Involved in protein refolding and response to heat. Predicted to be active in cytoplasm and nucleus. Is expressed in adult head. Orthologous to human HSPB6 (heat shock protein family B (small) member 6). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
all
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Genomic context

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See CG7409 in Genome Data Viewer
Location:
66A12-66A12; 3-21 cM
Exon count:
1
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (7754409..7755168)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (7747509..7748268)

Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Sensory neuron membrane protein 2 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Henna Neighboring gene Clock

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Effects of different small HSPB members on contractile dysfunction and structural changes in a Drosophila melanogaster model for Atrial Fibrillation. Zhang D, et al. J Mol Cell Cardiol, 2011 Sep. PMID 21745477
  2. Drosophila small heat shock proteins: cell and organelle-specific chaperones? Michaud S, et al. Prog Mol Subcell Biol, 2002. PMID 11908067
  3. Specific protein homeostatic functions of small heat-shock proteins increase lifespan. Vos MJ, et al. Aging Cell, 2016 Apr. PMID 26705243, Free PMC Article
  4. The small heat shock protein (sHSP) genes in the silkworm, Bombyx mori, and comparative analysis with other insect sHSP genes. Li ZW, et al. BMC Evol Biol, 2009 Aug 28. PMID 19715580, Free PMC Article
  5. Developmental Expression and Functions of the Small Heat Shock Proteins in Drosophila. Jagla T, et al. Int J Mol Sci, 2018 Nov 2. PMID 30400176, Free PMC Article

See all (41) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables unfolded protein binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables unfolded protein binding ISM
Inferred from Sequence Model
more info
 PubMed 
Process Evidence Code Pubs
involved_in chaperone-mediated protein folding ISM
Inferred from Sequence Model
more info
 PubMed 
involved_in protein refolding IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in protein refolding IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in response to heat IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in response to heat IDA
Inferred from Direct Assay
more info
 PubMed 
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG7409-PA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_037436.4 Reference assembly

    Range
    7754409..7755168
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_139898.2 → NP_648155.1  uncharacterized protein Dmel_CG7409 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_648155.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VSA9
    Related
    FBpp0076522
    Conserved Domains (1) summary
    cd06526
    Location:54 → 131
    metazoan_ACD; Alpha-crystallin domain (ACD) of metazoan alpha-crystallin-type small(s) heat shock proteins (Hsps). sHsps are small stress induced proteins with monomeric masses between 12 -43 kDa, whose common feature is the Alpha-crystallin domain (ACD). sHsps are ...
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9VSA9 Q9VSA9

Gene LinkOut

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