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tbcc-1 C-CAP/cofactor C-like domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 3896741, updated on 2-Nov-2024

Summary

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Official Symbol
tbcc-1
Official Full Name
C-CAP/cofactor C-like domain-containing protein
Primary source
WormBase:WBGene00044609
Locus tag
CELE_Y71H2AM.24
See related
AllianceGenome:WB:WBGene00044609
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to be involved in protein folding and tubulin complex assembly. Predicted to be active in cytoplasm. Orthologous to human TBCC (tubulin folding cofactor C). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See tbcc-1 in Genome Data Viewer
Location:
chromosome: III
Exon count:
7
Sequence:
Chromosome: III; NC_003281.10 (2788441..2792973)

Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene Cytochrome oxidase c subunit VIb Neighboring gene NADH dehydrogenase [ubiquinone] 1 subunit C2 Neighboring gene Potassium channel domain-containing protein Neighboring gene Peptidase C1A papain C-terminal domain-containing protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003281.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Depletion of endogenously biotinylated carboxylases enhances the sensitivity of TurboID-mediated proximity labeling in Caenorhabditis elegans. Artan M, et al. J Biol Chem, 2022 Sep. PMID 35933017, Free PMC Article
  2. Interactome analysis of Caenorhabditis elegans synapses by TurboID-based proximity labeling. Artan M, et al. J Biol Chem, 2021 Sep. PMID 34416233, Free PMC Article
  3. Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules. Cipriani PG, et al. Elife, 2021 Jul 5. PMID 34223818, Free PMC Article
  4. EPIC: software toolkit for elution profile-based inference of protein complexes. Hu LZ, et al. Nat Methods, 2019 Aug. PMID 31308550, Free PMC Article
  5. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Process Evidence Code Pubs
involved_in post-chaperonin tubulin folding pathway IEA
Inferred from Electronic Annotation
more info
  
involved_in protein folding IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in tubulin complex assembly IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
C-CAP/cofactor C-like domain-containing protein
NP_001033383.3
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003281.10 Reference assembly

    Range
    2788441..2792973
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001038294.4 → NP_001033383.3  C-CAP/cofactor C-like domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001033383.3

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q3V5J2
    Conserved Domains (1) summary
    pfam07986
    Location:166 → 278
    TBCC; Tubulin binding cofactor C
Nucleotide Protein
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