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osbpl2.S oxysterol binding protein like 2 S homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 398688, updated on 4-Nov-2024

Summary

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Official Symbol
osbpl2.S
Official Full Name
oxysterol binding protein like 2 S homeolog
Primary source
Xenbase:XB-GENE-17340977
Locus tag
XELAEV_18046233mg
See related
EnsemblRapid:ENSXLAG00005031590 AllianceGenome:Xenbase:XB-GENE-17340977
Gene type
protein coding
RefSeq status
PREDICTED
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Summary
Predicted to enable cholesterol binding activity. Predicted to act upstream of or within lipid transport. Predicted to be located in cytosol; perinuclear endoplasmic reticulum; and plasma membrane. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness 67. Orthologous to human OSBPL2 (oxysterol binding protein like 2). [provided by Alliance of Genome Resources, Nov 2024]
Annotation information
Annotation category: partial on reference assembly
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Genomic context

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See osbpl2.S in Genome Data Viewer
Location:
chromosome: 9_10S
Exon count:
13
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 9_10S NC_054388.1 (13539716..13563142, complement)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 9_10S NC_030741.1 (13438043..13490854, complement)

Chromosome 9_10S - NC_054388.1Genomic Context describing neighboring genes Neighboring gene laminin subunit alpha 5 S homeolog Neighboring gene ADRM1 26S proteasome ubiquitin receptor S homeolog Neighboring gene histamine receptor H3 S homeolog Neighboring gene synovial sarcoma translocation gene on chromosome 18-like 1 S homeolog

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables cholesterol binding IEA
Inferred from Electronic Annotation
more info
  
enables lipid binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within lipid transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
  
located_in intracellular membrane-bounded organelle IEA
Inferred from Electronic Annotation
more info
  
located_in perinuclear endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
  
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
uncharacterized protein LOC398688

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001089264.1 → NP_001082733.1  uncharacterized protein LOC398688

    See identical proteins and their annotated locations for NP_001082733.1

    Status: PREDICTED

    Source sequence(s)
    BC073379
    UniProtKB/TrEMBL
    A0A974BTA4, Q6GNX2, Q7T0Z8
    Related
    ENSXLAP00005094974.1, ENSXLAT00005096690.1
    Conserved Domains (1) summary
    pfam01237
    Location:75 → 463
    Oxysterol_BP; Oxysterol-binding protein

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054388.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    13539716..13563142 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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