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C11orf87 chromosome 11 open reading frame 87 [ Homo sapiens (human) ]

Gene ID: 399947, updated on 2-Nov-2024

Summary

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Official Symbol
C11orf87provided by HGNC
Official Full Name
chromosome 11 open reading frame 87provided by HGNC
Primary source
HGNC:HGNC:33788
See related
Ensembl:ENSG00000185742 AllianceGenome:HGNC:33788
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
NEURIM1; LOH11CR1A
Summary
Predicted to be located in membrane. [provided by Alliance of Genome Resources, Nov 2024]
Expression
Restricted expression toward brain (RPKM 7.9) See more
Orthologs
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Genomic context

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See C11orf87 in Genome Data Viewer
Location:
11q22.3
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 11 NC_000011.10 (109422190..109429167)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 11 NC_060935.1 (109432359..109439336)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 11 NC_000011.9 (109292916..109299893)

Chromosome 11 - NC_000011.10Genomic Context describing neighboring genes Neighboring gene RNA, 5S ribosomal pseudogene 349 Neighboring gene uncharacterized LOC124900307 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr11:109261364-109261957 Neighboring gene chaperonin containing TCP1 subunit 6 pseudogene 5 Neighboring gene MPRA-validated peak1462 silencer Neighboring gene long intergenic non-protein coding RNA 2715

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: HPA RNA-seq normal tissues HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Methylomic analysis identifies C11orf87 as a novel epigenetic biomarker for GI cancers.
    Title: Methylomic analysis identifies C11orf87 as a novel epigenetic biomarker for GI cancers.
  2. Suppression of miR-147b contributed to H37Rv-infected macrophage viability and migration in tuberculosis in vitro.
    Title: Suppression of miR-147b contributed to H37Rv-infected macrophage viability and migration in tuberculosis in vitro.
Submit: New GeneRIF Correction

Phenotypes

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Find tests for this gene in the NIH Genetic Testing Registry (GTR)

Review eQTL and phenotype association data in this region using PheGenI

EBI GWAS Catalog

Description
Biological insights from 108 schizophrenia-associated genetic loci.
EBI GWAS Catalog

Variation

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See Variation Viewer (GRCh37.p13)

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Clone Names

  • FLJ33767

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
uncharacterized protein C11orf87
Names
neuronal integral membrane protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_207645.4 → NP_997528.2  uncharacterized protein C11orf87 precursor

    See identical proteins and their annotated locations for NP_997528.2

    Status: VALIDATED

    Source sequence(s)
    AB096240, AK091086, AK303693, BC035798, DA221578, DA232989
    Consensus CDS
    CCDS31672.1
    UniProtKB/Swiss-Prot
    B4E169, Q6NUJ2
    UniProtKB/TrEMBL
    A0A158RFU1
    Related
    ENSP00000331581.6, ENST00000327419.7
    Conserved Domains (1) summary
    pfam06365
    Location:56 → 100
    CD34_antigen; CD34/Podocalyxin family

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000011.10 Reference GRCh38.p14 Primary Assembly

    Range
    109422190..109429167
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011542818.3 → XP_011541120.1  uncharacterized protein C11orf87 isoform X2

    See identical proteins and their annotated locations for XP_011541120.1

    UniProtKB/Swiss-Prot
    B4E169, Q6NUJ2
    UniProtKB/TrEMBL
    A0A158RFU1
    Conserved Domains (1) summary
    pfam06365
    Location:56 → 100
    CD34_antigen; CD34/Podocalyxin family

  2. XM_011542817.3 → XP_011541119.1  uncharacterized protein C11orf87 isoform X1

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060935.1 Alternate T2T-CHM13v2.0

    Range
    109432359..109439336
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054368764.1 → XP_054224739.1  uncharacterized protein C11orf87 isoform X2

    UniProtKB/Swiss-Prot
    B4E169, Q6NUJ2
    UniProtKB/TrEMBL
    A0A158RFU1

  2. XM_054368763.1 → XP_054224738.1  uncharacterized protein C11orf87 isoform X1

Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q6NUJ2.2 GenPept UniProtKB/Swiss-Prot:Q6NUJ2

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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