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rabl3 RAB, member of RAS oncogene family-like 3 [ Danio rerio (zebrafish) ]

Gene ID: 403048, updated on 12-Sep-2024

Summary

Official Symbol
rabl3provided by ZNC
Official Full Name
RAB, member of RAS oncogene family-like 3provided by ZNC
Primary source
ZFIN:ZDB-GENE-040808-11
See related
Ensembl:ENSDARG00000040959 AllianceGenome:ZFIN:ZDB-GENE-040808-11
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
fb40b02; wu:fb40b02; zgc:100876
Summary
Predicted to enable GTP binding activity; GTPase activity; and protein homodimerization activity. Predicted to be involved in several processes, including lymphocyte differentiation; regulation of Ras protein signal transduction; and regulation of protein lipidation. Predicted to act upstream of or within proteolysis. Predicted to be active in endomembrane system. Human ortholog(s) of this gene implicated in pancreatic cancer. Orthologous to human RABL3 (RAB, member of RAS oncogene family like 3). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

See rabl3 in Genome Data Viewer
Location:
chromosome: 9
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 9 NC_007120.7 (32649104..32652419)
105 previous assembly GRCz10 (GCF_000002035.5) 9 NC_007120.6 (32838372..32841670)

Chromosome 9 - NC_007120.7Genomic Context describing neighboring genes Neighboring gene SATB homeobox 2 Neighboring gene DnaJ heat shock protein family (Hsp40) member B11 Neighboring gene granzyme 3, tandem duplicate 2 Neighboring gene granzyme 3, tandem duplicate 1

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

General gene information

Markers

Clone Names

  • MGC100876

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables GTP binding IEA
Inferred from Electronic Annotation
more info
 
enables GTP binding ISS
Inferred from Sequence or Structural Similarity
more info
 
enables GTPase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
enables protein homodimerization activity ISS
Inferred from Sequence or Structural Similarity
more info
 
Process Evidence Code Pubs
involved_in B cell differentiation ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in T cell differentiation in thymus ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in intracellular protein transport IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in natural killer cell differentiation ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in regulation of Ras protein signal transduction ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in regulation of protein lipidation ISS
Inferred from Sequence or Structural Similarity
more info
 
Component Evidence Code Pubs
is_active_in endomembrane system IBA
Inferred from Biological aspect of Ancestor
more info
 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_205733.1NP_991296.1  rab-like protein 3

    See identical proteins and their annotated locations for NP_991296.1

    Status: PROVISIONAL

    Source sequence(s)
    AY391440
    UniProtKB/Swiss-Prot
    Q6TNS7
    Related
    ENSDARP00000115081.1, ENSDART00000136136.3
    Conserved Domains (1) summary
    cd04102
    Location:7210
    RabL3; Rab GTPase-like family 3 (Rab-like3)

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007120.7 Reference GRCz11 Primary Assembly

    Range
    32649104..32652419
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_068223354.1XP_068079455.1  rab-like protein 3 isoform X1