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tlr9 - toll-like receptor 9

Predicted to enable pattern recognition receptor activity. Acts upstream of or within antibacterial humoral response and toll-like receptor signaling pathway. Located in endoplasmic reticulum. Is expressed in several structures, including blood; eye; heart; liver; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in several diseases, including allergic bronchopulmonary aspergillosis; cystic fibrosis; glomerulonephritis (multiple); hepatitis B; and lung disease (multiple). Orthologous to human TLR9 (toll like receptor 9). [provided by Alliance of Genome Resources, Oct 2024]

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Species Gene Architecture aa