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IL13RA2 interleukin 13 receptor subunit alpha 2 [ Canis lupus familiaris (dog) ]

Gene ID: 403622, updated on 5-Mar-2024

Summary

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Official Symbol
IL13RA2provided by VGNC
Official Full Name
interleukin 13 receptor subunit alpha 2provided by VGNC
Primary source
VGNC:VGNC:41938
See related
Ensembl:ENSCAFG00845016176
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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See IL13RA2 in Genome Data Viewer
Location:
chromosome: X
Exon count:
18
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) X NC_051843.1 (89462267..89540412, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) X NC_006621.4 (73868563..73897928, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) X NC_049260.1 (88414159..88443524, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) X NC_049299.1 (86906747..86936111, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) X NC_049780.1 (88581088..88610454, complement)

Chromosome X - NC_051843.1Genomic Context describing neighboring genes Neighboring gene 5-hydroxytryptamine receptor 2C Neighboring gene COUP transcription factor 2-like Neighboring gene microRNA mir-448 Neighboring gene U6 spliceosomal RNA Neighboring gene transcription factor BTF3-like Neighboring gene small nucleolar RNA SNORA35 Neighboring gene leucine rich repeats and calponin homology domain containing 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Molecular cloning of canine IL-13 receptor alpha chain (alpha1 and alpha2) cDNAs and detection of corresponding mRNAs in canine tissues. Tang L. Vet Immunol Immunopathol, 2001 May 30. PMID 11389954
  2. Immunopathogenic pathways in canine inflammatory myopathies resemble human myositis. Shelton GD, et al. Vet Immunol Immunopathol, 2006 Sep 15. PMID 16797723

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables cytokine receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cytokine-mediated signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in external side of plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
interleukin-13 receptor subunit alpha-2
Names
IL-13 receptor subunit alpha-2
IL-13R subunit alpha-2
IL-13R-alpha-2
IL-13RA2
interleukin 13 receptor alpha chain 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001003075.2 → NP_001003075.1  interleukin-13 receptor subunit alpha-2 precursor

    See identical proteins and their annotated locations for NP_001003075.1

    Status: VALIDATED

    Source sequence(s)
    AF314533, CX990270, DN269329, DN341626
    UniProtKB/Swiss-Prot
    Q3HTU7, Q95LF0
    UniProtKB/TrEMBL
    A0A8C0JW16, A0A8C0STV3, A0A8I3P275
    Related
    ENSCAFP00845022834.1, ENSCAFT00845029028.1
    Conserved Domains (1) summary
    pfam09240
    Location:141 → 234
    IL6Ra-bind; Interleukin-6 receptor alpha chain, binding

RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051843.1 Reference ROS_Cfam_1.0

    Range
    89462267..89540412 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038448795.1 → XP_038304723.1  interleukin-13 receptor subunit alpha-2 isoform X1

    UniProtKB/TrEMBL
    A0A8I3NZM4, A0A8P0TMQ2
    Conserved Domains (2) summary
    cd00063
    Location:237 → 326
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam09240
    Location:141 → 234
    IL6Ra-bind; Interleukin-6 receptor alpha chain, binding

  2. XM_038448801.1 → XP_038304729.1  interleukin-13 receptor subunit alpha-2 isoform X3

    UniProtKB/TrEMBL
    A0A8C0SSY0, A0A8I3NZM4, A0A8I3S1Z3, A0A8P0TMQ2
    Conserved Domains (1) summary
    pfam09240
    Location:141 → 234
    IL6Ra-bind; Interleukin-6 receptor alpha chain, binding

  3. XM_038448800.1 → XP_038304728.1  interleukin-13 receptor subunit alpha-2 isoform X3

    UniProtKB/TrEMBL
    A0A8C0SSY0, A0A8I3NZM4, A0A8I3S1Z3, A0A8P0TMQ2
    Conserved Domains (1) summary
    pfam09240
    Location:141 → 234
    IL6Ra-bind; Interleukin-6 receptor alpha chain, binding

  4. XM_038448796.1 → XP_038304724.1  interleukin-13 receptor subunit alpha-2 isoform X2

    UniProtKB/TrEMBL
    A0A8C0STV3, A0A8I3P275
    Conserved Domains (2) summary
    cd00063
    Location:257 → 347
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam09240
    Location:161 → 254
    IL6Ra-bind; Interleukin-6 receptor alpha chain, binding

  5. XM_038448798.1 → XP_038304726.1  interleukin-13 receptor subunit alpha-2 isoform X3

    UniProtKB/TrEMBL
    A0A8C0SSY0, A0A8I3NZM4, A0A8I3S1Z3, A0A8P0TMQ2
    Conserved Domains (1) summary
    pfam09240
    Location:141 → 234
    IL6Ra-bind; Interleukin-6 receptor alpha chain, binding

  6. XM_038448799.1 → XP_038304727.1  interleukin-13 receptor subunit alpha-2 isoform X3

    UniProtKB/TrEMBL
    A0A8C0SSY0, A0A8I3NZM4, A0A8I3S1Z3, A0A8P0TMQ2
    Related
    ENSCAFP00845022643.1, ENSCAFT00845028771.1
    Conserved Domains (1) summary
    pfam09240
    Location:141 → 234
    IL6Ra-bind; Interleukin-6 receptor alpha chain, binding

  7. XM_038448797.1 → XP_038304725.1  interleukin-13 receptor subunit alpha-2 isoform X3

    UniProtKB/TrEMBL
    A0A8C0SSY0, A0A8I3NZM4, A0A8I3S1Z3, A0A8P0TMQ2
    Conserved Domains (1) summary
    pfam09240
    Location:141 → 234
    IL6Ra-bind; Interleukin-6 receptor alpha chain, binding

  8. XM_038448803.1 → XP_038304731.1  interleukin-13 receptor subunit alpha-2 isoform X5

    UniProtKB/Swiss-Prot
    Q3HTU7, Q95LF0
    UniProtKB/TrEMBL
    A0A8C0JW16, A0A8C0STV3, A0A8I3P275
    Conserved Domains (1) summary
    pfam09240
    Location:141 → 234
    IL6Ra-bind; Interleukin-6 receptor alpha chain, binding

  9. XM_038448804.1 → XP_038304732.1  interleukin-13 receptor subunit alpha-2 isoform X6

    UniProtKB/TrEMBL
    A0A8I3NZM4, A0A8P0TMQ2
    Conserved Domains (1) summary
    pfam09240
    Location:141 → 234
    IL6Ra-bind; Interleukin-6 receptor alpha chain, binding

  10. XM_038448802.1 → XP_038304730.1  interleukin-13 receptor subunit alpha-2 isoform X4

    UniProtKB/TrEMBL
    A0A8I3NZM4, A0A8P0TMQ2
    Conserved Domains (2) summary
    cd00063
    Location:237 → 327
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam09240
    Location:141 → 234
    IL6Ra-bind; Interleukin-6 receptor alpha chain, binding

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049299.1 Alternate UMICH_Zoey_3.1

    Range
    86906747..86936111 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049780.1 Alternate UNSW_CanFamBas_1.0

    Range
    88581088..88610454 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049260.1 Alternate UU_Cfam_GSD_1.0

    Range
    88414159..88443524 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006621.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    73868563..73897928 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q95LF0.1 GenPept UniProtKB/Swiss-Prot:Q95LF0

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