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SSR2 signal sequence receptor subunit 2 [ Canis lupus familiaris (dog) ]

Gene ID: 403950, updated on 17-Aug-2024

Summary

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Official Symbol
SSR2provided by VGNC
Official Full Name
signal sequence receptor subunit 2provided by VGNC
Primary source
VGNC:VGNC:46838
See related
Ensembl:ENSCAFG00845010530
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Also known as
gp25H; SSR-beta; TRAP-beta
Orthologs
human mouse all
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Genomic context

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See SSR2 in Genome Data Viewer
Location:
chromosome: 7
Exon count:
9
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 7 NC_051811.1 (41656990..41668191)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 7 NC_006589.4 (41284537..41290952)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 7 NC_049228.1 (41780416..41786822)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 7 NC_049267.1 (41442596..41449006)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 7 NC_049748.1 (41496229..41502635)

Chromosome 7 - NC_051811.1Genomic Context describing neighboring genes Neighboring gene late endosomal/lysosomal adaptor, MAPK and MTOR activator 2 Neighboring gene ubiquilin 4 Neighboring gene uncharacterized LOC102151322 Neighboring gene Rho/Rac guanine nucleotide exchange factor 2 Neighboring gene uncharacterized LOC119876447 Neighboring gene 60S ribosomal protein L31-like

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The signal sequence receptor has a second subunit and is part of a translocation complex in the endoplasmic reticulum as probed by bifunctional reagents. Görlich D, et al. J Cell Biol, 1990 Dec. PMID 2177473, Free PMC Article
  2. SSR alpha and associated calnexin are major calcium binding proteins of the endoplasmic reticulum membrane. Wada I, et al. J Biol Chem, 1991 Oct 15. PMID 1918067
  3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Component Evidence Code Pubs
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
translocon-associated protein subunit beta
Names
glycoprotein 25H
signal sequence receptor beta subunit

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001003269.2 → NP_001003269.1  translocon-associated protein subunit beta precursor

    See identical proteins and their annotated locations for NP_001003269.1

    Status: VALIDATED

    Source sequence(s)
    CO679178, DN431908, DN869892
    UniProtKB/Swiss-Prot
    P23438
    UniProtKB/TrEMBL
    A0A8C0JXR5
    Related
    ENSCAFP00845014487.1, ENSCAFT00845018570.1
    Conserved Domains (1) summary
    pfam05753
    Location:4 → 179
    TRAP_beta; Translocon-associated protein beta (TRAPB)

RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051811.1 Reference ROS_Cfam_1.0

    Range
    41656990..41668191
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038670491.1 → XP_038526419.1  translocon-associated protein subunit beta isoform X2

    Conserved Domains (1) summary
    pfam05753
    Location:27 → 182
    TRAP_beta; Translocon-associated protein beta (TRAPB)

  2. XM_038670489.1 → XP_038526417.1  translocon-associated protein subunit beta isoform X1

    Conserved Domains (1) summary
    pfam05753
    Location:4 → 208
    TRAP_beta; Translocon-associated protein beta (TRAPB)

  3. XM_038670488.1 → XP_038526416.1  translocon-associated protein subunit beta isoform X1

    Conserved Domains (1) summary
    pfam05753
    Location:4 → 208
    TRAP_beta; Translocon-associated protein beta (TRAPB)

  4. XM_038670490.1 → XP_038526418.1  translocon-associated protein subunit beta isoform X1

    Conserved Domains (1) summary
    pfam05753
    Location:4 → 208
    TRAP_beta; Translocon-associated protein beta (TRAPB)

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049267.1 Alternate UMICH_Zoey_3.1

    Range
    41442596..41449006
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049748.1 Alternate UNSW_CanFamBas_1.0

    Range
    41496229..41502635
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049228.1 Alternate UU_Cfam_GSD_1.0

    Range
    41780416..41786822
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006589.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    41284537..41290952
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P23438.1 GenPept UniProtKB/Swiss-Prot:P23438

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