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rcc1 regulator of chromosome condensation 1 [ Danio rerio (zebrafish) ]

Gene ID: 406457, updated on 18-Sep-2024

Summary

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Official Symbol
rcc1provided by ZNC
Official Full Name
regulator of chromosome condensation 1provided by ZNC
Primary source
ZFIN:ZDB-GENE-040426-2216
See related
Ensembl:ENSDARG00000037158 AllianceGenome:ZFIN:ZDB-GENE-040426-2216
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
Chc1; fj77f08; zgc:65796; zgc:77114; wu:fj77f08
Summary
Predicted to enable guanyl-nucleotide exchange factor activity. Predicted to be active in cytoplasm. Is expressed in several structures, including central nervous system; head; immature eye; neural tube; and pectoral fin musculature. Orthologous to human RCC1 (regulator of chromosome condensation 1). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
human mouse all
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Genomic context

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See rcc1 in Genome Data Viewer
Location:
chromosome: 16
Exon count:
10
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 16 NC_007127.7 (34185613..34194967, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 16 NC_007127.6 (34231579..34240946, complement)

Chromosome 16 - NC_007127.7Genomic Context describing neighboring genes Neighboring gene transcription elongation factor A (SII), 3 Neighboring gene opioid receptor, delta 1b Neighboring gene phosphatase and actin regulator 4b Neighboring gene endothelin-2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Repetitive Elements Trigger RIG-I-like Receptor Signaling that Regulates the Emergence of Hematopoietic Stem and Progenitor Cells. Lefkopoulos S, et al. Immunity, 2020 Nov 17. PMID 33159854
  2. Comprehensive expression map of transcription regulators in the adult zebrafish telencephalon reveals distinct neurogenic niches. Diotel N, et al. J Comp Neurol, 2015 Jun 1. PMID 25556858, Free PMC Article
  3. Hematopoietic gene expression profile in zebrafish kidney marrow. Song HD, et al. Proc Natl Acad Sci U S A, 2004 Nov 16. PMID 15520368, Free PMC Article
  4. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables guanyl-nucleotide exchange factor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within cell division IEA
Inferred from Electronic Annotation
more info
  
involved_in regulation of mitotic cell cycle IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in regulation of mitotic spindle assembly IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
regulator of chromosome condensation
Names
chromosome condensation 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_213178.1 → NP_998343.1  regulator of chromosome condensation

    See identical proteins and their annotated locations for NP_998343.1

    Status: PROVISIONAL

    Source sequence(s)
    BC066721
    UniProtKB/TrEMBL
    Q6NY65, Q6PBB0
    Related
    ENSDARP00000054025.4, ENSDART00000054026.5
    Conserved Domains (2) summary
    COG5184
    Location:3 → 415
    ATS1; Alpha-tubulin suppressor and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton]
    pfam00415
    Location:361 → 411
    RCC1; Regulator of chromosome condensation (RCC1) repeat

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007127.7 Reference GRCz11 Primary Assembly

    Range
    34185613..34194967 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017351335.3 → XP_017206824.1  regulator of chromosome condensation isoform X1

    UniProtKB/TrEMBL
    Q6NY65, Q6PBB0
    Conserved Domains (2) summary
    COG5184
    Location:3 → 415
    ATS1; Alpha-tubulin suppressor and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton]
    pfam00415
    Location:361 → 411
    RCC1; Regulator of chromosome condensation (RCC1) repeat
Nucleotide Protein
Heading Accession and Version

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