TRPC5 transient receptor potential cation channel subfamily C member 5 [Bos taurus (domestic cattle)] - Gene

Summary

Official Symbol: TRPC5provided by VGNC
Official Full Name: transient receptor potential cation channel subfamily C member 5provided by VGNC
Primary source: VGNC:VGNC:36385
See related: BGD:BT12543; Ensembl:ENSBTAG00000010065
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Bos taurus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Also known as: trp
Orthologs: human mouse all
NEW: Try the new Gene table
Try the new Transcript table

Genomic context

Location:: chromosome: X

Exon count:: 11

Annotation release	Status	Assembly	Chr	Location
RS_2023_09	current	ARS-UCD2.0 (GCF_002263795.3)	X	NC_037357.1 (59966892..60322797, complement)

Chromosome X - NC_037357.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to reference sequence details

Genomic Sequence:: NC_037357.1 Chromosome X Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the page Help

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Nitrix oxide can negatively modulate endogenous TRPC5-containing channels through an indirect mechanism.
Title: Nitric oxide lacks direct effect on TRPC5 channels but suppresses endogenous TRPC5-containing channels in endothelial cells.
analysis of a TRPC6-TRPC5 channel cascade that restricts endothelial cell movement
Title: Elucidation of a TRPC6-TRPC5 channel cascade that restricts endothelial cell movement.

Submit: New GeneRIF Correction

General gene information

Go to the top of the page Help

Markers

RM350 (e-PCR), detects polymorphism
- UniSTS:75313

Trpc5 (e-PCR), detects polymorphism
- UniSTS:516716

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables inositol 1,4,5 trisphosphate binding	IEA Inferred from Electronic Annotation more info	PubMed
enables protein binding	IEA Inferred from Electronic Annotation more info	PubMed
enables store-operated calcium channel activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in calcium ion transmembrane transport	IEA Inferred from Electronic Annotation more info	PubMed
involved_in manganese ion transport	IEA Inferred from Electronic Annotation more info	PubMed
involved_in regulation of cytosolic calcium ion concentration	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
part_of cation channel complex	IEA Inferred from Electronic Annotation more info	PubMed
located_in membrane	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

Go to the top of the page Help

Preferred Names: short transient receptor potential channel 5

Names: transient receptor potential channel 5

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001166574.1 → NP_001160046.1 short transient receptor potential channel 5

See identical proteins and their annotated locations for NP_001160046.1

Status: PROVISIONAL

Source sequence(s)

NKLS02000030

UniProtKB/TrEMBL

F1MTE6

Related

ENSBTAP00000013270.4, ENSBTAT00000013270.6

Conserved Domains (2) summary

TIGR00870
Location:17 → 756

trp; transient-receptor-potential calcium channel protein

sd00045
Location:35 → 67

ANK; ANK repeat [structural motif]