MAN2A1 - mannosidase alpha class 2A member 1
This gene encodes a glycosyl hydrolase that localizes to the Golgi and catalyzes the final hydrolytic step in the asparagine-linked oligosaccharide (N-glycan) maturation pathway. Mutations in the mouse homolog of this gene have been shown to cause a systemic autoimmune disease similar to human systemic lupus erythematosus. [provided by RefSeq, Dec 2013]
NCBI Orthologs
How was this calculated?genes for:
Protein alignment
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Species | Gene | Architecture | aa |
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