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lbe - ladybird early

Enables DNA-binding transcription factor activity, RNA polymerase II-specific. Involved in several processes, including imaginal disc morphogenesis; myoblast fusion; and regulation of myoblast fusion. Located in nucleus. Is expressed in several structures, including anal pad primordium; cuboidal/columnar epithelium; segment; somatic muscle cell; and somatic precursor cell. Human ortholog(s) of this gene implicated in congenital central hypoventilation syndrome. Orthologous to several human genes including LBX1 (ladybird homeobox 1). [provided by Alliance of Genome Resources, Oct 2024]

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Species Gene Architecture aa