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Gprin2 G protein regulated inducer of neurite outgrowth 2 [ Mus musculus (house mouse) ]

Gene ID: 432839, updated on 2-Nov-2024

Summary

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Official Symbol
Gprin2provided by MGI
Official Full Name
G protein regulated inducer of neurite outgrowth 2provided by MGI
Primary source
MGI:MGI:2444560
See related
Ensembl:ENSMUSG00000071531 AllianceGenome:MGI:2444560
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Gm286; mKIAA0514; C230073P13; C130040D06Rik
Summary
Predicted to be involved in neuron projection development. Predicted to be active in plasma membrane. Orthologous to human GPRIN2 (G protein regulated inducer of neurite outgrowth 2). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in CNS E18 (RPKM 2.6), whole brain E14.5 (RPKM 2.3) and 11 other tissues See more
Orthologs
human all
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Genomic context

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See Gprin2 in Genome Data Viewer
Location:
14 B; 14 20.8 cM
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 14 NC_000080.7 (33907645..33923649, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 14 NC_000080.6 (34185688..34201692, complement)

Chromosome 14 - NC_000080.7Genomic Context describing neighboring genes Neighboring gene ribosomal protein L23A, pseudogene 3 Neighboring gene BRCA1/BRCA2-containing complex, subunit 3 pseudogene Neighboring gene STARR-seq mESC enhancer starr_36364 Neighboring gene VISTA enhancer mm340 Neighboring gene synaptotagmin XV Neighboring gene shieldin complex subunit 2 Neighboring gene STARR-seq mESC enhancer starr_36366 Neighboring gene zinc finger, DHHC domain containing 17 pseudogene

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Maternal high-fat diet-induced microbiota changes are associated with alterations in embryonic brain metabolites and adolescent behaviour. Ratsika A, et al. Brain Behav Immun, 2024 Oct. PMID 39032541
  2. Database resources of the National Center for Biotechnology Information. Wheeler DL, et al. Nucleic Acids Res, 2001 Jan 1. PMID 11125038, Free PMC Article
  3. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
  4. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
  5. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636

See all (12) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

General gene information

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Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in neuron projection development IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
G protein-regulated inducer of neurite outgrowth 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_183209.3 → NP_899032.2  G protein-regulated inducer of neurite outgrowth 2

    See identical proteins and their annotated locations for NP_899032.2

    Status: VALIDATED

    Source sequence(s)
    AC154738
    Consensus CDS
    CCDS49443.1
    UniProtKB/TrEMBL
    A0A2I3BRN2
    Related
    ENSMUSP00000154640.2, ENSMUST00000226613.2
    Conserved Domains (1) summary
    pfam15235
    Location:347 → 447
    GRIN_C; G protein-regulated inducer of neurite outgrowth C-terminus

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000080.7 Reference GRCm39 C57BL/6J

    Range
    33907645..33923649 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006519212.2 → XP_006519275.1  G protein-regulated inducer of neurite outgrowth 2 isoform X1

    See identical proteins and their annotated locations for XP_006519275.1

    UniProtKB/TrEMBL
    A0A2I3BRN2
    Conserved Domains (1) summary
    pfam15235
    Location:347 → 447
    GRIN_C; G protein-regulated inducer of neurite outgrowth C-terminus

  2. XM_006519213.5 → XP_006519276.1  G protein-regulated inducer of neurite outgrowth 2 isoform X1

    See identical proteins and their annotated locations for XP_006519276.1

    UniProtKB/TrEMBL
    A0A2I3BRN2
    Conserved Domains (1) summary
    pfam15235
    Location:347 → 447
    GRIN_C; G protein-regulated inducer of neurite outgrowth C-terminus

  3. XM_011245111.1 → XP_011243413.1  G protein-regulated inducer of neurite outgrowth 2 isoform X1

    See identical proteins and their annotated locations for XP_011243413.1

    UniProtKB/TrEMBL
    A0A2I3BRN2
    Conserved Domains (1) summary
    pfam15235
    Location:347 → 447
    GRIN_C; G protein-regulated inducer of neurite outgrowth C-terminus

  4. XM_006519215.5 → XP_006519278.1  G protein-regulated inducer of neurite outgrowth 2 isoform X1

    See identical proteins and their annotated locations for XP_006519278.1

    UniProtKB/TrEMBL
    A0A2I3BRN2
    Conserved Domains (1) summary
    pfam15235
    Location:347 → 447
    GRIN_C; G protein-regulated inducer of neurite outgrowth C-terminus
Nucleotide Protein Strain
Heading Accession and Version

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