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Tmem178b transmembrane protein 178B [ Mus musculus (house mouse) ]

Gene ID: 434008, updated on 2-Nov-2024

Summary

Official Symbol
Tmem178bprovided by MGI
Official Full Name
transmembrane protein 178Bprovided by MGI
Primary source
MGI:MGI:3647581
See related
Ensembl:ENSMUSG00000057716 AllianceGenome:MGI:3647581
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Gm5567; EG434008; A930009E05Rik
Summary
Predicted to be active in membrane. Is expressed in cortical plate; dorsal root ganglion; and spinal cord. Orthologous to human TMEM178B (transmembrane protein 178B). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in CNS E18 (RPKM 7.1), cortex adult (RPKM 6.9) and 7 other tissues See more
Orthologs
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Genomic context

See Tmem178b in Genome Data Viewer
Location:
6 B1; 6 18.82 cM
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 6 NC_000072.7 (39848164..40232084)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 6 NC_000072.6 (39871230..40255150)

Chromosome 6 - NC_000072.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_15673 Neighboring gene predicted gene 7554 Neighboring gene aldolase A, fructose-bisphosphate pseudogene Neighboring gene STARR-seq mESC enhancer starr_15674 Neighboring gene STARR-seq mESC enhancer starr_15675 Neighboring gene STARR-seq mESC enhancer starr_15676 Neighboring gene STARR-seq mESC enhancer starr_15678 Neighboring gene STARR-seq mESC enhancer starr_15681 Neighboring gene STARR-seq mESC enhancer starr_15684 Neighboring gene acylglycerol kinase Neighboring gene DENN domain containing 11 Neighboring gene WEE1 homolog 2 (S. pombe)

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (1) 

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
 
Component Evidence Code Pubs
is_active_in membrane IBA
Inferred from Biological aspect of Ancestor
more info
 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001004182.4NP_001004182.1  transmembrane protein 178B isoform 2

    See identical proteins and their annotated locations for NP_001004182.1

    Status: VALIDATED

    Source sequence(s)
    AC153728, AK084030, BC051426
    Consensus CDS
    CCDS39465.1
    UniProtKB/TrEMBL
    Q8BNC6
    Related
    ENSMUSP00000055268.7, ENSMUST00000061740.8
    Conserved Domains (1) summary
    cl21598
    Location:2111
    PMP22_Claudin; PMP-22/EMP/MP20/Claudin family
  2. NM_001360978.1NP_001347907.1  transmembrane protein 178B isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC153377, AC153728, AC155655, BC051426, CD349317
    Consensus CDS
    CCDS90039.1
    UniProtKB/TrEMBL
    A0A5F8MQ13
    Related
    ENSMUSP00000159180.2, ENSMUST00000239008.2
    Conserved Domains (1) summary
    cl21598
    Location:100266
    PMP22_Claudin; PMP-22/EMP/MP20/Claudin family

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000072.7 Reference GRCm39 C57BL/6J

    Range
    39848164..40232084
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006506361.4XP_006506424.1  transmembrane protein 178B isoform X1

    See identical proteins and their annotated locations for XP_006506424.1