RTL8B retrotransposon Gag like 8B [Homo sapiens (human)] - Gene

Summary

Official Symbol: RTL8Bprovided by HGNC
Official Full Name: retrotransposon Gag like 8Bprovided by HGNC
Primary source: HGNC:HGNC:33156
See related: Ensembl:ENSG00000212747 AllianceGenome:HGNC:33156
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Homo sapiens
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as: CXX1c; MAR8B; SIRH4; FAM127C
Summary: Predicted to be active in nucleolus. [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: all
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Genomic context

Location:: Xq26.3

Exon count:: 1

Annotation release	Status	Assembly	Chr	Location
RS_2023_10	current	GRCh38.p14 (GCF_000001405.40)	X	NC_000023.11 (135020513..135022542, complement)
RS_2023_10	current	T2T-CHM13v2.0 (GCF_009914755.1)	X	NC_060947.1 (133345880..133347909, complement)
105.20220307	previous assembly	GRCh37.p13 (GCF_000001405.25)	X	NC_000023.10 (134154543..134156572, complement)

Chromosome X - NC_000023.11 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

RTL8 promotes nuclear localization of UBQLN2 to subnuclear compartments associated with protein quality control.
Title: RTL8 promotes nuclear localization of UBQLN2 to subnuclear compartments associated with protein quality control.

Submit: New GeneRIF Correction

Phenotypes

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Find tests for this gene in the NIH Genetic Testing Registry (GTR)

Review eQTL and phenotype association data in this region using PheGenI

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Gene Ontology Provided by GOA

Function	Evidence Code	Pubs
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed

General protein information

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Preferred Names: retrotransposon Gag-like protein 8B

Names: Sushi-Ichi retrotransposon homolog 1; family with sequence similarity 127 member C; mammalian retrotransposon derived protein 8B; mammalian retrotransposon-derived 2; protein FAM127C

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.