OR2I1P olfactory receptor family 2 subfamily I member 1 pseudogene [Homo sapiens (human)] - Gene

Summary

Official Symbol: OR2I1Pprovided by HGNC
Official Full Name: olfactory receptor family 2 subfamily I member 1 pseudogeneprovided by HGNC
Primary source: HGNC:HGNC:8258
See related: Ensembl:ENSG00000237988 AllianceGenome:HGNC:8258
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Homo sapiens
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as: OR2I1; OR2I2; OR2I6; OR6-1; OR2I3P; OR2I4P; OR2I5P; OR2I7P; OR2I8P; OR2I9P; OR6-34; HS6M1-14
Summary: Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
Orthologs: mouse all
NEW: Try the new Gene table
Try the new Transcript table

Genomic context

Location:: 6p22.1

Exon count:: 2

Annotation release	Status	Assembly	Chr	Location
RS_2023_10	current	GRCh38.p14 (GCF_000001405.40)	6	NC_000006.12 (29550407..29557773)
RS_2023_10	current	T2T-CHM13v2.0 (GCF_009914755.1)	6	NC_060930.1 (29425069..29432457)
105.20220307	previous assembly	GRCh37.p13 (GCF_000001405.25)	6	NC_000006.11 (29518184..29525550)

Chromosome 6 - NC_000006.12 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the page Help

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

Phenotypes

Go to the top of the page Help

Review eQTL and phenotype association data in this region using PheGenI

EBI GWAS Catalog

Description
Genome-wide association study in Han Chinese identifies three novel loci for human height. EBI GWAS Catalog EBI GWAS CatalogPubMed

Variation

Go to the top of the page Help

See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

General gene information

Go to the top of the page Help

Markers

RH80188 (e-PCR)
- UniSTS:88906

RH93978 (e-PCR)
- UniSTS:84930

Gene Ontology Provided by GOA

Function	Evidence Code	Pubs
enables G protein-coupled receptor activity	IEA Inferred from Electronic Annotation more info
enables olfactory receptor activity	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in G protein-coupled receptor signaling pathway	IEA Inferred from Electronic Annotation more info
involved_in detection of chemical stimulus involved in sensory perception of smell	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in plasma membrane	IBA Inferred from Biological aspect of Ancestor more info

General protein information

Go to the top of the page Help

Preferred Names: putative olfactory receptor 2I1

Names: olfactory receptor OR6-1 pseudogene; olfactory receptor OR6-34 pseudogene; olfactory receptor, family 2, subfamily I, member 2; olfactory receptor, family 2, subfamily I, member 3 pseudogene; olfactory receptor, family 2, subfamily I, member 4 pseudogene; olfactory receptor, family 2, subfamily I, member 5 pseudogene; olfactory receptor, family 2, subfamily I, member 6; olfactory receptor, family 2, subfamily I, member 7 pseudogene; olfactory receptor, family 2, subfamily I, member 8 pseudogene; olfactory receptor, family 2, subfamily I, member 9 pseudogene; putative olfactory receptor 2I2; putative olfactory receptor 2I3; putative olfactory receptor 2I4; seven transmembrane helix receptor

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001396058.1 → NP_001382987.1 putative olfactory receptor 2I1

Status: VALIDATED

Source sequence(s)

AL645936, AL662860

Consensus CDS

CCDS93877.1

UniProtKB/Swiss-Prot

Q8NGU4

UniProtKB/TrEMBL

A0A2R8Y4D9

Related

ENSP00000493715.1, ENST00000641137.2

Conserved Domains (1) summary

cd15433
Location:24 → 301

7tmA_OR2Y-like; olfactory receptor subfamily 2Y and related proteins, member of the class A family of seven-transmembrane G protein-coupled receptors