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LOC442497 uncharacterized LOC442497 [ Homo sapiens (human) ]

Gene ID: 442497, updated on 10-Oct-2023

Summary

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Gene symbol
LOC442497
Gene description
uncharacterized LOC442497
See related
Ensembl:ENSG00000249574
Gene type
ncRNA
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Expression
Low expression observed in reference dataset See more
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Genomic context

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Location:
7p22.3
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 7 NC_000007.14 (379425..382879)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 7 NC_060931.1 (479911..483365)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 7 NC_000007.13 (419391..422845)

Chromosome 7 - NC_000007.14Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105375118 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 17804 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr7:373151-373812 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr7:373813-374472 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr7:376155-376966 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr7:376967-377776 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr7:383559-384188 Neighboring gene uncharacterized LOC124901809 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr7:392059-392793 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr7:404760-405260 Neighboring gene ReSE screen-validated silencer GRCh37_chr7:405696-405911 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr7:408996-409520 Neighboring gene MPRA-validated peak6332 silencer Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr7:431351-431892 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr7:454774-455322 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr7:460048-460804 Neighboring gene uncharacterized LOC116435278 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr7:465509-466426 Neighboring gene uncharacterized LOC112267991 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr7:473022-473858 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr7:473859-474694 Neighboring gene MED14-independent group 3 enhancer GRCh37_chr7:475441-476640 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr7:485302-485962 Neighboring gene uncharacterized LOC124901566

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

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Related articles in PubMed

  1. PRP19 transforms into a sensor of RPA-ssDNA after DNA damage and drives ATR activation via a ubiquitin-mediated circuitry. Maréchal A, et al. Mol Cell, 2014 Jan 23. PMID 24332808, Free PMC Article
  2. Defining the Protein-Protein Interaction Network of the Human Protein Tyrosine Phosphatase Family. Li X, et al. Mol Cell Proteomics, 2016 Sep. PMID 27432908, Free PMC Article
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. Ota T, et al. Nat Genet, 2004 Jan. PMID 14702039

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Genotypes

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Clone Names

  • AC226118.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_033960.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AK092540
    Related
    ENST00000515213.1

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000007.14 Reference GRCh38.p14 Primary Assembly

    Range
    379425..382879
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060931.1 Alternate T2T-CHM13v2.0

    Range
    479911..483365
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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Chemical Information
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Research Materials