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MT-TN mitochondrially encoded tRNA asparagine [ Homo sapiens (human) ]

Gene ID: 4570, updated on 15-Apr-2024

Summary

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Official Symbol
MT-TNprovided by HGNC
Official Full Name
mitochondrially encoded tRNA asparagineprovided by HGNC
Primary source
HGNC:HGNC:7493
See related
MIM:590010; AllianceGenome:HGNC:7493
Gene type
tRNA
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
MTTN; TRNN
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Genomic context

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Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) MT (non-nuclear) NC_012920.1 (5657..5729, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) MT (non-nuclear) NC_012920.1 (5657..5729, complement)

Chromosome MT - NC_012920.1Genomic Context describing neighboring genes Neighboring gene tRNA-Trp Neighboring gene tRNA-Ala Neighboring gene tRNA-Cys Neighboring gene tRNA-Tyr

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Progressive external ophthalmoplegia associated with novel MT-TN mutations. Visuttijai K, et al. Acta Neurol Scand, 2021 Jan. PMID 32869280, Free PMC Article
  2. Comprehensive analysis of common mitochondrial DNA variants and colorectal cancer risk. Webb E, et al. Br J Cancer, 2008 Dec 16. PMID 19050702, Free PMC Article
  3. MtSNPscore: a combined evidence approach for assessing cumulative impact of mitochondrial variations in disease. Bhardwaj A, et al. BMC Bioinformatics, 2009 Aug 27. PMID 19758471, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. MT-TN mutations lead to progressive mitochondrial encephalopathy and promotes mitophagy.
    Title: MT-TN mutations lead to progressive mitochondrial encephalopathy and promotes mitophagy.
  2. Progressive external ophthalmoplegia associated with novel MT-TN mutations.
    Title: Progressive external ophthalmoplegia associated with novel MT-TN mutations.
  3. Observational study of gene-disease association. (HuGE Navigator)
    Title: MtSNPscore: a combined evidence approach for assessing cumulative impact of mitochondrial variations in disease.
Submit: New GeneRIF Correction

Phenotypes

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Find tests for this gene in the NIH Genetic Testing Registry (GTR)

Review eQTL and phenotype association data in this region using PheGenI

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

General gene information

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Markers

  • NAR: 0297

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Other Literature Sources
Molecular Biology Databases