wdfy1 WD repeat and FYVE domain containing 1 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: wdfy1provided by ZNC
Official Full Name: WD repeat and FYVE domain containing 1provided by ZNC
Primary source: ZFIN:ZDB-GENE-041024-4
See related: Ensembl:ENSDARG00000005425 AllianceGenome:ZFIN:ZDB-GENE-041024-4
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: zgc:101764; zgc:109909
Summary: Predicted to enable metal ion binding activity. Predicted to be located in early endosome. Orthologous to human WDFY1 (WD repeat and FYVE domain containing 1). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: human mouse all
NEW: Try the new Gene table
Try the new Transcript table

Genomic context

Location:: chromosome: 15

Exon count:: 12

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	15	NC_007126.7 (43208122..43237698, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	15	NC_007126.6 (43327144..43356720, complement)

Chromosome 15 - NC_007126.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help

See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

Go to the top of the page Help

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

Go to the top of the page Help

Markers

fi34g12.x1 (e-PCR)
- UniSTS:204559

fi38d04.x1 (e-PCR)
- UniSTS:197423

G40192 (e-PCR)
- UniSTS:3209

fi34g12.x1 (e-PCR)
- UniSTS:197351

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables metal ion binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in positive regulation of toll-like receptor 3 signaling pathway	IBA Inferred from Biological aspect of Ancestor more info
involved_in positive regulation of toll-like receptor 4 signaling pathway	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in early endosome	IBA Inferred from Biological aspect of Ancestor more info

General protein information

Go to the top of the page Help

Preferred Names: WD repeat and FYVE domain-containing protein 1

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001007057.2 → NP_001007058.2 WD repeat and FYVE domain-containing protein 1

Status: VALIDATED

Source sequence(s)

CU657924, EH538062, EH559286, FO704834

UniProtKB/TrEMBL

A0A8M1N300, Q4VBV0

Related

ENSDARP00000006309.5, ENSDART00000027019.8

Conserved Domains (5) summary

smart00320
Location:355 → 394

WD40; WD40 repeats

COG2319
Location:20 → 394

WD40; WD40 repeat [General function prediction only]

cd15756
Location:279 → 354

FYVE_WDFY1; FYVE domain found in WD40 repeat and FYVE domain-containing protein 1 (WDFY1) and similar proteins

sd00039
Location:28 → 67

7WD40; WD40 repeat [structural motif]

cl02567
Location:16 → 275

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...