HTRA2 HtrA serine peptidase 2 [Canis lupus familiaris (dog)] - Gene

Summary

Official Symbol: HTRA2provided by VGNC
Official Full Name: HtrA serine peptidase 2provided by VGNC
Primary source: VGNC:VGNC:41836
See related: Ensembl:ENSCAFG00845018463
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Canis lupus familiaris (sub-species: familiaris)
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 17

Exon count:: 8

Annotation release	Status	Assembly	Chr	Location
106	current	ROS_Cfam_1.0 (GCF_014441545.1)	17	NC_051821.1 (49469859..49472851, complement)
106	current	Dog10K_Boxer_Tasha (GCF_000002285.5)	17	NC_006599.4 (48252304..48255295, complement)
106	current	UU_Cfam_GSD_1.0 (GCF_011100685.1)	17	NC_049238.1 (49111429..49114422, complement)
106	current	UMICH_Zoey_3.1 (GCF_005444595.1)	17	NC_049277.1 (48487009..48490000, complement)
106	current	UNSW_CanFamBas_1.0 (GCF_013276365.1)	17	NC_049758.1 (48553751..48556744, complement)

Chromosome 17 - NC_051821.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

MARC_5801-5802:991939731:1 (e-PCR)
- UniSTS:231172

MARC_5801-5802:997299306:1 (e-PCR)
- UniSTS:231172

D2S1958E (e-PCR)
- UniSTS:153730

AUP1 (e-PCR)
- UniSTS:278014

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables protein binding	IEA Inferred from Electronic Annotation more info	PubMed
enables serine-type endopeptidase activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in positive regulation of apoptotic process	IEA Inferred from Electronic Annotation more info	PubMed
involved_in programmed cell death	IEA Inferred from Electronic Annotation more info	PubMed
involved_in proteolysis	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in mitochondrion	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: serine protease HTRA2, mitochondrial

Names: protease serine 25

NP_001271389.1

EC 2.4.21.-

EC 3.4.21.108

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.