PRKAR2B protein kinase cAMP-dependent type II regulatory subunit beta [Canis lupus familiaris (dog)] - Gene

Summary

Official Symbol: PRKAR2Bprovided by VGNC
Official Full Name: protein kinase cAMP-dependent type II regulatory subunit betaprovided by VGNC
Primary source: VGNC:VGNC:44977
See related: Ensembl:ENSCAFG00845026498
Gene type: protein coding
RefSeq status: MODEL
Organism: Canis lupus familiaris (sub-species: familiaris)
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 18

Exon count:: 11

Annotation release	Status	Assembly	Chr	Location
106	current	ROS_Cfam_1.0 (GCF_014441545.1)	18	NC_051822.1 (13645633..13738378, complement)
106	current	Dog10K_Boxer_Tasha (GCF_000002285.5)	18	NC_006600.4 (13024300..13116617, complement)
106	current	UU_Cfam_GSD_1.0 (GCF_011100685.1)	18	NC_049239.1 (13659873..13752991, complement)
106	current	UMICH_Zoey_3.1 (GCF_005444595.1)	18	NC_049278.1 (13461865..13554232, complement)
106	current	UNSW_CanFamBas_1.0 (GCF_013276365.1)	18	NC_049759.1 (13382039..13474442, complement)

Chromosome 18 - NC_051822.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

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Pathways from PubChem

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General gene information

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Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables cAMP-dependent protein kinase regulator activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in regulation of protein phosphorylation	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
part_of cAMP-dependent protein kinase complex	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: cAMP-dependent protein kinase type II-beta regulatory subunit

XP_013976258.1

EC 2.7.11.1

XP_038279722.1

EC 2.7.11.1

XP_038279723.1

EC 2.7.11.1

XP_038356078.1

EC 2.7.11.1

XP_038356079.1

EC 2.7.11.1

XP_038418637.1

EC 2.7.11.1

XP_038418638.1

EC 2.7.11.1

XP_038482743.1

EC 2.7.11.1

XP_038482744.1

EC 2.7.11.1

XP_858066.2

EC 2.7.11.1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

NC_051822.1 Reference ROS_Cfam_1.0

Range

13645633..13738378 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038423795.1 → XP_038279723.1 cAMP-dependent protein kinase type II-beta regulatory subunit isoform X2

UniProtKB/TrEMBL

A0A8C0LBP9, A0A8C0YXX8, A0A8I3PT74, A0A8I3S5X1, A0A8P0NYY0

Related

ENSCAFP00845036662.1, ENSCAFT00845046722.1

Conserved Domains (2) summary

cd12104
Location:3 → 43

DD_RIIbeta_PKA; Dimerization/Docking domain of the Type II beta Regulatory subunit of cAMP-dependent protein kinase

cd00038
Location:275 → 395

CAP_ED; effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO ...
XM_038423794.1 → XP_038279722.1 cAMP-dependent protein kinase type II-beta regulatory subunit isoform X1

UniProtKB/TrEMBL

A0A8I3PT74, A0A8P0NYY0

Conserved Domains (2) summary

cd12104
Location:3 → 43

DD_RIIbeta_PKA; Dimerization/Docking domain of the Type II beta Regulatory subunit of cAMP-dependent protein kinase

cd00038
Location:293 → 413

CAP_ED; effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO ...

Alternate UMICH_Zoey_3.1

Genomic

NC_049278.1 Alternate UMICH_Zoey_3.1

Range

13461865..13554232 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038500151.1 → XP_038356079.1 cAMP-dependent protein kinase type II-beta regulatory subunit isoform X2

Conserved Domains (2) summary

cd12104
Location:3 → 43

DD_RIIbeta_PKA; Dimerization/Docking domain of the Type II beta Regulatory subunit of cAMP-dependent protein kinase

cd00038
Location:275 → 395

CAP_ED; effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO ...
XM_038500150.1 → XP_038356078.1 cAMP-dependent protein kinase type II-beta regulatory subunit isoform X1

Conserved Domains (2) summary

cd12104
Location:3 → 43

DD_RIIbeta_PKA; Dimerization/Docking domain of the Type II beta Regulatory subunit of cAMP-dependent protein kinase

cd00038
Location:293 → 413

CAP_ED; effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO ...

Alternate UNSW_CanFamBas_1.0

Genomic

NC_049759.1 Alternate UNSW_CanFamBas_1.0

Range

13382039..13474442 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038626816.1 → XP_038482744.1 cAMP-dependent protein kinase type II-beta regulatory subunit isoform X2

Conserved Domains (2) summary

cd12104
Location:3 → 43

DD_RIIbeta_PKA; Dimerization/Docking domain of the Type II beta Regulatory subunit of cAMP-dependent protein kinase

cd00038
Location:275 → 395

CAP_ED; effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO ...
XM_038626815.1 → XP_038482743.1 cAMP-dependent protein kinase type II-beta regulatory subunit isoform X1

Conserved Domains (2) summary

cd12104
Location:3 → 43

DD_RIIbeta_PKA; Dimerization/Docking domain of the Type II beta Regulatory subunit of cAMP-dependent protein kinase

cd00038
Location:293 → 413

CAP_ED; effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO ...

Alternate UU_Cfam_GSD_1.0

Genomic

NC_049239.1 Alternate UU_Cfam_GSD_1.0

Range

13659873..13752991 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038562710.1 → XP_038418638.1 cAMP-dependent protein kinase type II-beta regulatory subunit isoform X2

UniProtKB/TrEMBL

A0A8C0LBP9, A0A8C0YXX8, A0A8I3PT74, A0A8I3S5X1, A0A8P0NYY0

Conserved Domains (2) summary

cd12104
Location:3 → 43

DD_RIIbeta_PKA; Dimerization/Docking domain of the Type II beta Regulatory subunit of cAMP-dependent protein kinase

cd00038
Location:275 → 395

CAP_ED; effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO ...
XM_038562709.1 → XP_038418637.1 cAMP-dependent protein kinase type II-beta regulatory subunit isoform X1

UniProtKB/TrEMBL

A0A8I3PT74, A0A8P0NYY0

Conserved Domains (2) summary

cd12104
Location:3 → 43

DD_RIIbeta_PKA; Dimerization/Docking domain of the Type II beta Regulatory subunit of cAMP-dependent protein kinase

cd00038
Location:293 → 413

CAP_ED; effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO ...

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

NC_006600.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

Range

13024300..13116617 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_852973.6 → XP_858066.2 cAMP-dependent protein kinase type II-beta regulatory subunit isoform X2

UniProtKB/TrEMBL

A0A8C0LBP9, A0A8C0YXX8, A0A8I3PT74, A0A8I3S5X1, A0A8P0NYY0

Conserved Domains (2) summary

cd12104
Location:3 → 43

DD_RIIbeta_PKA; Dimerization/Docking domain of the Type II beta Regulatory subunit of cAMP-dependent protein kinase

cd00038
Location:275 → 395

CAP_ED; effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO ...
XM_014120783.3 → XP_013976258.1 cAMP-dependent protein kinase type II-beta regulatory subunit isoform X1

UniProtKB/TrEMBL

A0A8I3PT74, A0A8P0NYY0

Conserved Domains (2) summary

cd12104
Location:3 → 43

DD_RIIbeta_PKA; Dimerization/Docking domain of the Type II beta Regulatory subunit of cAMP-dependent protein kinase

cd00038
Location:293 → 413

CAP_ED; effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO ...