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MDV025 tegument serine/threonine protein kinase [ Gallid alphaherpesvirus 2 ]

Gene ID: 4811486, updated on 18-Aug-2023

Summary

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Gene symbol
MDV025
Gene description
tegument serine/threonine protein kinase
Locus tag
MD5V_025
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Gallid alphaherpesvirus 2 (strain: Md5, common: Marek's disease virus type 1, acronym: GaHV-2, acronym: MDV-1, nat-host: Gallus gallus)
Lineage
Viruses; Duplodnaviria; Heunggongvirae; Peploviricota; Herviviricetes; Herpesvirales; Herpesviridae; Alphaherpesvirinae; Mardivirus
Old locus tag
GaHV2Md5_gp025
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Genomic context

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Sequence:
NC_002229.3 (34544..37880, complement)

NC_002229.3Genomic Context describing neighboring genes Neighboring gene protein LORF2 Neighboring gene envelope glycoprotein L Neighboring gene uracil-DNA glycosylase Neighboring gene protein V57 Neighboring gene nuclear protein UL3 Neighboring gene nuclear protein UL4 Neighboring gene helicase-primase helicase subunit Neighboring gene capsid portal protein Neighboring gene tegument protein UL7 Neighboring gene helicase-primase subunit Neighboring gene DNA replication origin-binding helicase Neighboring gene envelope glycoprotein M Neighboring gene myristylated tegument protein Neighboring gene deoxyribonuclease Neighboring gene tegument protein UL14 Neighboring gene DNA packaging terminase subunit 1 Neighboring gene tegument protein UL16 Neighboring gene DNA packaging tegument protein UL17 Neighboring gene capsid triplex subunit 2 Neighboring gene major capsid protein Neighboring gene envelope protein UL20

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_002229.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Further analysis of Marek's disease virus horizontal transmission confirms that U(L)44 (gC) and U(L)13 protein kinase activity are essential, while U(S)2 is nonessential. Jarosinski KW, et al. J Virol, 2010 Aug. PMID 20484497, Free PMC Article
  2. The genome of a very virulent Marek's disease virus. Tulman ER, et al. J Virol, 2000 Sep. PMID 10933706, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. US2-negative mutants transmitted horizontally, eliminating US2 as being essential for the process. In contrast, the absence of gC or mutating the UL13 kinase activity abolished horizontal spread of Marek's disease virus between chickens.
    Title: Further analysis of Marek's disease virus horizontal transmission confirms that U(L)44 (gC) and U(L)13 protein kinase activity are essential, while U(S)2 is nonessential.
Submit: New GeneRIF Correction

General gene information

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regulatory

  • Loc: c34555-34550 regulatory_class = polyA_signal_sequence

General protein information

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Preferred Names
tegument serine/threonine protein kinase
YP_001033941.1
  • PK family

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_002229.3 Reference assembly

    Range
    34544..37880 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. YP_001033941.1 tegument serine/threonine protein kinase [Gallid alphaherpesvirus 2]

    See identical proteins and their annotated locations for YP_001033941.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    Q9E6Q4
    UniProtKB/TrEMBL
    G9CUC0, H6WUU4, Q6R5X6, Q9IBW2
    Conserved Domains (1) summary
    cl21453
    Location:152 → 297
    PKc_like; Protein Kinases, catalytic domain
Nucleotide Protein
Heading Accession and Version

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