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l(3)87Df lethal (3) 87Df [ Drosophila melanogaster (fruit fly) ]

Gene ID: 49762, updated on 28-Oct-2024

Summary

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Official Symbol
l(3)87Dfprovided by FlyBase
Official Full Name
lethal (3) 87Dfprovided by FlyBase
Primary source
FLYBASE:FBgn0002354
Locus tag
Dmel_CG7620
See related
AllianceGenome:FB:FBgn0002354
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
BcDNA:SD27354; CG7620; COX20; Dmel\CG7620; l(3)s12; l(3)S12; S12
Summary
Predicted to be involved in mitochondrial cytochrome c oxidase assembly. Predicted to be located in mitochondrial inner membrane. Predicted to be active in mitochondrion. Is expressed in adult head and organism. Human ortholog(s) of this gene implicated in mitochondrial complex IV deficiency nuclear type 11. Orthologous to human COX20 (cytochrome c oxidase assembly factor COX20). [provided by Alliance of Genome Resources, Oct 2024]
Orthologs
all
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Genomic context

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See l(3)87Df in Genome Data Viewer
Location:
87D9-87D9; 3-53 cM
Exon count:
3
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (13030913..13031598)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (8856635..8857320)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene C-terminal Binding Protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene rosy Neighboring gene uncharacterized protein Neighboring gene snake

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Aberrant splicing and altered spatial expression patterns in fruitless mutants of Drosophila melanogaster. Goodwin SF, et al. Genetics, 2000 Feb. PMID 10655225, Free PMC Article
  2. Organization of the rosy locus in Drosophila melanogaster: evidence for a control element adjacent to the xanthine dehydrogenase structural element. Chovnick A, et al. Genetics, 1976 Oct. PMID 826445, Free PMC Article
  3. Aberrant splicing and transcription termination caused by P element insertion into the intron of a Drosophila gene. Horowitz H, et al. Genetics, 1995 Jan. PMID 7705633, Free PMC Article
  4. Vectors for P element-mediated gene transfer in Drosophila. Rubin GM, et al. Nucleic Acids Res, 1983 Sep 24. PMID 6312420, Free PMC Article
  5. Genetic analysis of the right (3') end of the rosy locus in Drosophila melanogaster. Clark SH, et al. Genet Res, 1986 Apr. PMID 3086181

See all (58) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Process Evidence Code Pubs
involved_in mitochondrial cytochrome c oxidase assembly IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in mitochondrial cytochrome c oxidase assembly IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in mitochondrial inner membrane IEA
Inferred from Electronic Annotation
more info
  
is_active_in mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
lethal (3) 87Df
Names
CG7620-PA
l(3)87Df-PA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    13030913..13031598
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_080203.2 → NP_524942.1  lethal (3) 87Df [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_524942.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q26251, Q9VG00
    Related
    FBpp0082171
    Conserved Domains (1) summary
    pfam12597
    Location:19 → 102
    DUF3767; Protein of unknown function (DUF3767)
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q7JPT7 Q7JPT7
Q9VG00 Q9VG00

Gene LinkOut

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