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Gal3st4 galactose-3-O-sulfotransferase 4 [ Rattus norvegicus (Norway rat) ]

Gene ID: 498166, updated on 2-Nov-2024

Summary

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Official Symbol
Gal3st4provided by RGD
Official Full Name
galactose-3-O-sulfotransferase 4provided by RGD
Primary source
RGD:1561105
See related
EnsemblRapid:ENSRNOG00000001375 AllianceGenome:RGD:1561105
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1561105
Summary
Predicted to enable galactose 3-O-sulfotransferase activity. Predicted to be involved in glycolipid biosynthetic process. Predicted to act upstream of or within glycoprotein biosynthetic process. Predicted to be located in membrane. Orthologous to human GAL3ST4 (galactose-3-O-sulfotransferase 4). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Uterus (RPKM 20.7), Lung (RPKM 16.7) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Gal3st4 in Genome Data Viewer
Location:
12q11
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 12 NC_086030.1 (22381576..22390566, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 12 NC_051347.1 (17267963..17276951, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 12 NC_005111.4 (19583110..19592444, complement)

Chromosome 12 - NC_086030.1Genomic Context describing neighboring genes Neighboring gene late endosomal/lysosomal adaptor, MAPK and MTOR activator 4 Neighboring gene trafficking protein particle complex subunit 14 Neighboring gene glypican 2 Neighboring gene STAG3 cohesin complex component Neighboring gene uncharacterized LOC134481272

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Molecular cloning and characterization of a novel human galactose 3-O-sulfotransferase that transfers sulfate to gal beta 1-->3galNAc residue in O-glycans. Seko A, et al. J Biol Chem, 2001 Jul 13. PMID 11333265
  2. Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT). Gonzalez-Begne M, et al. J Proteome Res, 2009 Mar. PMID 19199708, Free PMC Article
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables galactose 3-O-sulfotransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables galactose 3-O-sulfotransferase activity ISO
Inferred from Sequence Orthology
more info
  
enables galactosylceramide sulfotransferase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in glycolipid biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within glycoprotein biosynthetic process ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
located_in membrane ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
galactose-3-O-sulfotransferase 4

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001109064.1 → NP_001102534.1  galactose-3-O-sulfotransferase 4

    See identical proteins and their annotated locations for NP_001102534.1

    Status: PROVISIONAL

    Source sequence(s)
    CH474107
    UniProtKB/TrEMBL
    A6KSU3, D3ZHZ0
    Related
    ENSRNOP00000001855.5, ENSRNOT00000001855.7
    Conserved Domains (1) summary
    cl22970
    Location:1 → 463
    Sulfotransfer_2; Sulfotransferase family

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086030.1 Reference GRCr8

    Range
    22381576..22390566 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039089699.2 → XP_038945627.1  galactose-3-O-sulfotransferase 4 isoform X4

    Conserved Domains (1) summary
    cl22970
    Location:1 → 220
    Sulfotransfer_2; Sulfotransferase family

  2. XM_006249025.4 → XP_006249087.1  galactose-3-O-sulfotransferase 4 isoform X1

    See identical proteins and their annotated locations for XP_006249087.1

    UniProtKB/TrEMBL
    A6KSU3, D3ZHZ0
    Conserved Domains (1) summary
    cl22970
    Location:1 → 463
    Sulfotransfer_2; Sulfotransferase family

  3. XM_006249026.5 → XP_006249088.1  galactose-3-O-sulfotransferase 4 isoform X2

    Related
    ENSRNOP00000099551.1, ENSRNOT00000161232.1
    Conserved Domains (1) summary
    cl22970
    Location:8 → 458
    Sulfotransfer_2; Sulfotransferase family

  4. XM_039089698.2 → XP_038945626.1  galactose-3-O-sulfotransferase 4 isoform X3

    Conserved Domains (1) summary
    cl22970
    Location:13 → 333
    Sulfotransfer_2; Sulfotransferase family
Nucleotide Protein Strain
Heading Accession and Version

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