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Firrm FIGNL1 interacting regulator of recombination and mitosis [ Rattus norvegicus (Norway rat) ]

Gene ID: 498265, updated on 10-Oct-2024

Summary

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Official Symbol
Firrmprovided by RGD
Official Full Name
FIGNL1 interacting regulator of recombination and mitosisprovided by RGD
Primary source
RGD:1563470
See related
EnsemblRapid:ENSRNOG00000059276 AllianceGenome:RGD:1563470
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
FLIP
Summary
Orthologous to human C1orf112 (chromosome 1 open reading frame 112). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Thymus (RPKM 65.2), Testes (RPKM 48.3) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Firrm in Genome Data Viewer
Location:
13q23
Exon count:
24
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 13 NC_086031.1 (78835081..78879022, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 13 NC_051348.1 (76301914..76345842, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 13 NC_005112.4 (82254516..82298467, complement)

Chromosome 13 - NC_086031.1Genomic Context describing neighboring genes Neighboring gene kinesin-associated protein 3 Neighboring gene uncharacterized LOC120096301 Neighboring gene SCY1 like pseudokinase 3 Neighboring gene uncharacterized LOC102555981 Neighboring gene methyltransferase 18, RPL3 N3(tau)-histidine Neighboring gene peptidylprolyl isomerase D, pseudogene 19

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables protein kinase binding ISO
Inferred from Sequence Orthology
more info
  
enables protein kinase binding ISS
Inferred from Sequence or Structural Similarity
more info
  
Process Evidence Code Pubs
involved_in chromosome segregation ISO
Inferred from Sequence Orthology
more info
  
involved_in interstrand cross-link repair ISO
Inferred from Sequence Orthology
more info
  
involved_in interstrand cross-link repair ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in mitotic cell cycle ISO
Inferred from Sequence Orthology
more info
  
involved_in mitotic cell cycle ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in regulation of protein kinase activity ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
located_in chromosome, centromeric region ISO
Inferred from Sequence Orthology
more info
  
located_in chromosome, centromeric region ISS
Inferred from Sequence or Structural Similarity
more info
  
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in kinetochore ISO
Inferred from Sequence Orthology
more info
  
located_in kinetochore ISS
Inferred from Sequence or Structural Similarity
more info
  
located_in midbody ISO
Inferred from Sequence Orthology
more info
  
located_in midbody ISS
Inferred from Sequence or Structural Similarity
more info
  
located_in nucleus ISO
Inferred from Sequence Orthology
more info
  
located_in nucleus ISS
Inferred from Sequence or Structural Similarity
more info
  
located_in spindle midzone ISO
Inferred from Sequence Orthology
more info
  
located_in spindle midzone ISS
Inferred from Sequence or Structural Similarity
more info
  

General protein information

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Preferred Names
FIGNL1-interacting regulator of recombination and mitosis
Names
FIDGETIN-like-1 interacting protein
POLO1-associating protein
uncharacterized protein C1orf112 homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001017493.1 → NP_001017493.1  FIGNL1-interacting regulator of recombination and mitosis isoform 1

    See identical proteins and their annotated locations for NP_001017493.1

    Status: PROVISIONAL

    Source sequence(s)
    BC083793
    UniProtKB/Swiss-Prot
    Q5XI94
    UniProtKB/TrEMBL
    A6IDC8
    Related
    ENSRNOP00000094621.1, ENSRNOT00000097617.2
    Conserved Domains (1) summary
    pfam14868
    Location:234 → 780
    DUF4487; Domain of unknown function (DUF4487)

  2. NM_001429949.1 → NP_001416878.1  FIGNL1-interacting regulator of recombination and mitosis isoform 2

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000013

RNA

  1. NR_190832.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000013

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086031.1 Reference GRCr8

    Range
    78835081..78879022 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_008769674.4 → XP_008767896.1  FIGNL1-interacting regulator of recombination and mitosis isoform X2

    Related
    ENSRNOP00000074557.3, ENSRNOT00000090120.3
    Conserved Domains (1) summary
    pfam14868
    Location:195 → 741
    DUF4487; Domain of unknown function (DUF4487)

  2. XM_008769673.4 → XP_008767895.3  FIGNL1-interacting regulator of recombination and mitosis isoform X1

    Related
    ENSRNOP00000100868.1, ENSRNOT00000167091.1

  3. XM_039090973.2 → XP_038946901.1  FIGNL1-interacting regulator of recombination and mitosis isoform X3

    Conserved Domains (1) summary
    pfam14868
    Location:6 → 449
    DUF4487; Domain of unknown function (DUF4487)

  4. XM_017598889.3 → XP_017454378.3  FIGNL1-interacting regulator of recombination and mitosis isoform X4

  5. XM_063272542.1 → XP_063128612.1  FIGNL1-interacting regulator of recombination and mitosis isoform X5

RNA

  1. XR_010056930.1 RNA Sequence

  2. XR_010056931.1 RNA Sequence

  3. XR_001840784.3 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q5XI94.1 GenPept UniProtKB/Swiss-Prot:Q5XI94

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