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Zfp518b zinc finger protein 518B [ Rattus norvegicus (Norway rat) ]

Gene ID: 498390, updated on 2-Nov-2024

Summary

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Official Symbol
Zfp518bprovided by RGD
Official Full Name
zinc finger protein 518Bprovided by RGD
Primary source
RGD:1564150
See related
EnsemblRapid:ENSRNOG00000028534 AllianceGenome:RGD:1564150
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1564150
Summary
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Orthologous to human ZNF518B (zinc finger protein 518B). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
human mouse all
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Genomic context

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See Zfp518b in Genome Data Viewer
Location:
14q21
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 14 NC_086032.1 (76333582..76352804)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 14 NC_051349.1 (72121085..72140479)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 14 NC_005113.4 (76853171..76872476)

Chromosome 14 - NC_086032.1Genomic Context describing neighboring genes Neighboring gene cytokine-dependent hematopoietic cell linker Neighboring gene U6 spliceosomal RNA Neighboring gene uncharacterized LOC120096632 Neighboring gene U6 spliceosomal RNA Neighboring gene non-POU domain containing, octamer-binding, pseudogene 12 Neighboring gene ribonucleotide reductase M1, pseudogene 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
  
enables RNA polymerase II transcription regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
zinc finger protein 518B

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001432825.1 → NP_001419754.1  zinc finger protein 518B

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000014
    UniProtKB/TrEMBL
    A6IJS9, D4ABC6

  2. NM_001432826.1 → NP_001419755.1  zinc finger protein 518B

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000014
    UniProtKB/TrEMBL
    A6IJS9, D4ABC6

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086032.1 Reference GRCr8

    Range
    76333582..76352804
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017599488.3 → XP_017454977.1  zinc finger protein 518B isoform X1

    Related
    ENSRNOP00000097304.1, ENSRNOT00000106470.2
    Conserved Domains (2) summary
    sd00017
    Location:140 → 160
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:179 → 200
    zf-H2C2_2; Zinc-finger double domain

  2. XM_008770231.4 → XP_008768453.1  zinc finger protein 518B isoform X1

    Related
    ENSRNOP00000099511.1, ENSRNOT00000157678.1
    Conserved Domains (2) summary
    sd00017
    Location:140 → 160
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:179 → 200
    zf-H2C2_2; Zinc-finger double domain

  3. XM_039092820.1 → XP_038948748.1  zinc finger protein 518B isoform X2

    Conserved Domains (2) summary
    sd00017
    Location:140 → 160
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13909
    Location:167 → 189
    zf-H2C2_5; C2H2-type zinc-finger domain

  4. XM_039092821.2 → XP_038948749.1  zinc finger protein 518B isoform X3

    Conserved Domains (2) summary
    sd00017
    Location:140 → 160
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13909
    Location:167 → 189
    zf-H2C2_5; C2H2-type zinc-finger domain

RNA

  1. XR_005493342.2 RNA Sequence

  2. XR_005493343.1 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version

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