Cmtm4 CKLF-like MARVEL transmembrane domain containing 4 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Cmtm4provided by RGD
Official Full Name: CKLF-like MARVEL transmembrane domain containing 4provided by RGD
Primary source: RGD:1565098
See related: EnsemblRapid:ENSRNOG00000011009 AllianceGenome:RGD:1565098
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: Cklfsf4; RGD1565098
Summary: Predicted to be active in membrane. Orthologous to human CMTM4 (CKLF like MARVEL transmembrane domain containing 4). [provided by Alliance of Genome Resources, Nov 2024]
Expression: Biased expression in Kidney (RPKM 235.8), Brain (RPKM 107.4) and 9 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 19p14

Exon count:: 4

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	19	NC_086037.1 (582642..622546)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	19	NC_051354.1 (576203..616109)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	19	NC_005118.4 (784618..824420)

Chromosome 19 - NC_086037.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Testosterone was associated with the expression of CMTM family during spermatogenesis, and CMTM2 and CMTM4 may take part in the spermatogenesis process.
Title: [Effect of testosterone on the expression of CMTM family of the male spermatogenesis suppression rats].

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General gene information

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Gene Ontology Provided by RGD

Component	Evidence Code	Pubs
is_active_in membrane	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: CKLF-like MARVEL transmembrane domain-containing protein 4

Names: chemokine-like factor super family 4

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001172151.3 → NP_001165622.1 CKLF-like MARVEL transmembrane domain-containing protein 4

Status: VALIDATED

Source sequence(s)

JAXUCZ010000019

UniProtKB/TrEMBL

A6JXV9, D4A110

Related

ENSRNOP00000099240.1, ENSRNOT00000154371.1

Conserved Domains (1) summary

pfam01284
Location:49 → 170

MARVEL; Membrane-associating domain