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Lrrc27 leucine rich repeat containing 27 [ Rattus norvegicus (Norway rat) ]

Gene ID: 499281, updated on 10-Oct-2024

Summary

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Official Symbol
Lrrc27provided by RGD
Official Full Name
leucine rich repeat containing 27provided by RGD
Primary source
RGD:1559981
See related
EnsemblRapid:ENSRNOG00000017538 AllianceGenome:RGD:1559981
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1559981
Summary
Orthologous to human LRRC27 (leucine rich repeat containing 27). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Testes (RPKM 273.5) and Heart (RPKM 29.8) See more
Orthologs
human mouse all
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Genomic context

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See Lrrc27 in Genome Data Viewer
Location:
1q41
Exon count:
13
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (203433463..203464683)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (194004967..194035087)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (211543751..211575823)

Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene dihydropyrimidinase-like 4 Neighboring gene serine/threonine kinase 32C Neighboring gene uncharacterized LOC120099954 Neighboring gene PWWP domain containing 2B Neighboring gene uncharacterized LOC134485192 Neighboring gene uncharacterized LOC134485193

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables actin binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in cardiac muscle cell development IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in cytoskeleton IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in sarcomere IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
leucine-rich repeat-containing protein 27

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001113789.2 → NP_001107261.2  leucine-rich repeat-containing protein 27 isoform b

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) has a distinct 3' coding region compared to variant 1. The resulting isoform (b) has a shorter and distinct C-terminus, compared to isoform a.
    Source sequence(s)
    JAXUCZ010000001
    UniProtKB/TrEMBL
    A6HXB1, D3ZDV5
    Conserved Domains (3) summary
    sd00031
    Location:50 → 69
    LRR_1; leucine-rich repeat [structural motif]
    pfam13855
    Location:68 → 127
    LRR_8; Leucine rich repeat
    cl26793
    Location:30 → 173
    PLN00113; leucine-rich repeat receptor-like protein kinase; Provisional

  2. NM_001143756.2 → NP_001137228.1  leucine-rich repeat-containing protein 27 isoform a

    See identical proteins and their annotated locations for NP_001137228.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (a).
    Source sequence(s)
    BC158629, JAXUCZ010000001
    UniProtKB/TrEMBL
    B0BN00
    Related
    ENSRNOP00000099036.1, ENSRNOT00000125021.1
    Conserved Domains (3) summary
    PLN00113
    Location:30 → 173
    PLN00113; leucine-rich repeat receptor-like protein kinase; Provisional
    sd00031
    Location:50 → 69
    LRR_1; leucine-rich repeat [structural motif]
    pfam13855
    Location:68 → 127
    LRR_8; Leucine rich repeat

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086019.1 Reference GRCr8

    Range
    203433463..203464683
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039087869.2 → XP_038943797.1  leucine-rich repeat-containing protein 27 isoform X1

    UniProtKB/TrEMBL
    B0BN00
    Conserved Domains (3) summary
    PLN00113
    Location:30 → 173
    PLN00113; leucine-rich repeat receptor-like protein kinase; Provisional
    sd00031
    Location:50 → 69
    LRR_1; leucine-rich repeat [structural motif]
    pfam13855
    Location:68 → 127
    LRR_8; Leucine rich repeat

  2. XM_063271537.1 → XP_063127607.1  leucine-rich repeat-containing protein 27 isoform X1

    UniProtKB/TrEMBL
    B0BN00

  3. XM_063271539.1 → XP_063127609.1  leucine-rich repeat-containing protein 27 isoform X2

  4. XM_063271541.1 → XP_063127611.1  leucine-rich repeat-containing protein 27 isoform X3

    UniProtKB/TrEMBL
    D3ZDV5

  5. XM_063271548.1 → XP_063127618.1  leucine-rich repeat-containing protein 27 isoform X3

    UniProtKB/TrEMBL
    D3ZDV5
    Related
    ENSRNOP00000048246.3, ENSRNOT00000049631.6

  6. XM_063271536.1 → XP_063127606.1  leucine-rich repeat-containing protein 27 isoform X1

    UniProtKB/TrEMBL
    B0BN00
    Related
    ENSRNOP00000023610.4, ENSRNOT00000023610.9

  7. XM_063271545.1 → XP_063127615.1  leucine-rich repeat-containing protein 27 isoform X3

    UniProtKB/TrEMBL
    D3ZDV5
Nucleotide Protein Strain
Heading Accession and Version

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