Majin membrane anchored junction protein [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Majinprovided by RGD
Official Full Name: membrane anchored junction proteinprovided by RGD
Primary source: RGD:1563886
See related: EnsemblRapid:ENSRNOG00000054336 AllianceGenome:RGD:1563886
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary: Predicted to enable DNA binding activity. Predicted to be involved in homologous chromosome pairing at meiosis and meiotic attachment of telomere to nuclear envelope. Predicted to act upstream of or within double-strand break repair involved in meiotic recombination; oogenesis; and spermatogenesis. Predicted to be located in chromosome, telomeric region and nuclear envelope. Predicted to be active in nuclear inner membrane. Orthologous to human MAJIN (membrane anchored junction protein). [provided by Alliance of Genome Resources, Nov 2024]
Expression: Biased expression in Testes (RPKM 8.2), Adrenal (RPKM 1.2) and 4 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 1q43

Exon count:: 9

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	1	NC_086019.1 (212917038..212953377)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	1	NC_051336.1 (203487777..203524098)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	1	NC_005100.4 (221540551..221594124)

Chromosome 1 - NC_086019.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables DNA binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within double-strand break repair involved in meiotic recombination	ISO Inferred from Sequence Orthology more info
involved_in homologous chromosome pairing at meiosis	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within homologous chromosome pairing at meiosis	ISO Inferred from Sequence Orthology more info
involved_in homologous chromosome pairing at meiosis	ISO Inferred from Sequence Orthology more info
involved_in homologous chromosome pairing at meiosis	ISS Inferred from Sequence or Structural Similarity more info
involved_in meiotic attachment of telomere to nuclear envelope	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within meiotic attachment of telomere to nuclear envelope	ISO Inferred from Sequence Orthology more info
involved_in meiotic attachment of telomere to nuclear envelope	ISO Inferred from Sequence Orthology more info
involved_in meiotic attachment of telomere to nuclear envelope	ISS Inferred from Sequence or Structural Similarity more info
involved_in meiotic telomere clustering	ISO Inferred from Sequence Orthology more info
involved_in meiotic telomere clustering	ISS Inferred from Sequence or Structural Similarity more info
acts_upstream_of_or_within oogenesis	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within spermatogenesis	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
located_in chromosome, telomeric region	ISO Inferred from Sequence Orthology more info
located_in chromosome, telomeric region	ISS Inferred from Sequence or Structural Similarity more info
located_in nuclear envelope	ISO Inferred from Sequence Orthology more info
is_active_in nuclear inner membrane	IBA Inferred from Biological aspect of Ancestor more info
located_in nuclear inner membrane	ISO Inferred from Sequence Orthology more info
located_in nuclear inner membrane	ISS Inferred from Sequence or Structural Similarity more info

General protein information

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Preferred Names: membrane-anchored junction protein

Names: hypothetical gene supported by BC078985; uncharacterized protein C11orf85 homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001024291.1 → NP_001019462.1 membrane-anchored junction protein

See identical proteins and their annotated locations for NP_001019462.1

Status: PROVISIONAL

Source sequence(s)

BC078985

UniProtKB/Swiss-Prot

Q6AYM7

UniProtKB/TrEMBL

A0A8I6GI71

Related

ENSRNOP00000072946.1, ENSRNOT00000077274.3

Conserved Domains (1) summary

pfam15077
Location:1 → 235

DUF4544; Domain of unknown function (DUF4544)

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

NC_086019.1 Reference GRCr8

Range

212917038..212953377

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_039087881.2 → XP_038943809.1 membrane-anchored junction protein isoform X1

Conserved Domains (1) summary

pfam15077
Location:1 → 189

MAJIN; Membrane-anchored junction protein