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Rnf208 ring finger protein 208 [ Rattus norvegicus (Norway rat) ]

Gene ID: 499748, updated on 17-Aug-2024

Summary

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Official Symbol
Rnf208provided by RGD
Official Full Name
ring finger protein 208provided by RGD
Primary source
RGD:1565957
See related
EnsemblRapid:ENSRNOG00000010607 AllianceGenome:RGD:1565957
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1565957
Summary
Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in protein autoubiquitination. Predicted to be located in cytosol and nucleoplasm. Orthologous to human RNF208 (ring finger protein 208). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Brain (RPKM 66.5), Kidney (RPKM 24.8) and 6 other tissues See more
Orthologs
human mouse all
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Genomic context

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Location:
3p13
Exon count:
2
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 3 NC_086021.1 (28455836..28457879)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 3 NC_051338.1 (8057808..8059721)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 3 NC_005102.4 (2462466..2463790)

Chromosome 3 - NC_086021.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC120101506 Neighboring gene solute carrier family 34 member 3 Neighboring gene ring finger protein 224 Neighboring gene cysteine rich tail 1 Neighboring gene RING finger protein 208 Neighboring gene NADPH dependent diflavin oxidoreductase 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Protein microarray characterization of the S-nitrosoproteome. Lee YI, et al. Mol Cell Proteomics, 2014 Jan. PMID 24105792, Free PMC Article
  2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables ubiquitin protein ligase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables ubiquitin-protein transferase activity ISO
Inferred from Sequence Orthology
more info
  
Process Evidence Code Pubs
involved_in protein autoubiquitination ISO
Inferred from Sequence Orthology
more info
  
involved_in protein ubiquitination IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in cytosol ISO
Inferred from Sequence Orthology
more info
  
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
RING finger protein 208

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001109195.1 → NP_001102665.1  RING finger protein 208

    See identical proteins and their annotated locations for NP_001102665.1

    Status: PROVISIONAL

    Source sequence(s)
    CH474001
    UniProtKB/TrEMBL
    A6JT22, D4ADR3
    Related
    ENSRNOP00000014087.3, ENSRNOT00000014087.6
    Conserved Domains (1) summary
    cd16559
    Location:144 → 197
    RING-HC_RNF208; RING finger, HC subclass, found in RING finger protein 208 (RNF208) and similar proteins

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086021.1 Reference GRCr8

    Range
    28455836..28457879
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039105655.2 → XP_038961583.1  RING finger protein 208 isoform X1

    UniProtKB/TrEMBL
    A6JT22, D4ADR3
    Related
    ENSRNOP00000090406.1, ENSRNOT00000108034.2
    Conserved Domains (1) summary
    cd16559
    Location:144 → 197
    RING-HC_RNF208; RING finger, HC subclass, found in RING finger protein 208 (RNF208) and similar proteins
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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