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Clec1a C-type lectin domain family 1, member A [ Rattus norvegicus (Norway rat) ]

Gene ID: 500337, updated on 17-Aug-2024

Summary

Official Symbol
Clec1aprovided by RGD
Official Full Name
C-type lectin domain family 1, member Aprovided by RGD
Primary source
RGD:1566110
See related
EnsemblRapid:ENSRNOG00000060460 AllianceGenome:RGD:1566110
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1566110
Summary
Predicted to enable carbohydrate binding activity. Predicted to be integral component of membrane. Human ortholog(s) of this gene implicated in aspergillosis. Orthologous to human CLEC1A (C-type lectin domain family 1 member A). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Lung (RPKM 253.8), Heart (RPKM 82.4) and 7 other tissues See more
Orthologs
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Genomic context

Location:
4q42
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 4 NC_086022.1 (164561385..164588593, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 4 NC_051339.1 (162875360..162902571, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 4 NC_005103.4 (163191503..163214678, complement)

Chromosome 4 - NC_086022.1Genomic Context describing neighboring genes Neighboring gene C-type lectin domain family 1, member B Neighboring gene C-type lectin domain containing 9A Neighboring gene uncharacterized LOC120102409 Neighboring gene C-type lectin domain containing 7A Neighboring gene oxidized low density lipoprotein receptor 1

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Markers

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables carbohydrate binding IEA
Inferred from Electronic Annotation
more info
 
enables transmembrane signaling receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
involved_in signal transduction IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
C-type lectin domain family 1 member A

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001109253.1NP_001102723.1  C-type lectin domain family 1 member A

    See identical proteins and their annotated locations for NP_001102723.1

    Status: PROVISIONAL

    Source sequence(s)
    CH473964
    UniProtKB/TrEMBL
    A6IM48, D3ZGU3
    Related
    ENSRNOP00000069193.1, ENSRNOT00000091602.3
    Conserved Domains (1) summary
    cd03593
    Location:136258
    CLECT_NK_receptors_like; C-type lectin-like domain (CTLD) of the type found in natural killer cell receptors (NKRs)

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086022.1 Reference GRCr8

    Range
    164561385..164588593 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039108218.2XP_038964146.1  C-type lectin domain family 1 member A isoform X1

    UniProtKB/TrEMBL
    A6IM48, D3ZGU3
    Conserved Domains (1) summary
    cd03593
    Location:136258
    CLECT_NK_receptors_like; C-type lectin-like domain (CTLD) of the type found in natural killer cell receptors (NKRs)
  2. XM_039108217.2XP_038964145.1  C-type lectin domain family 1 member A isoform X1

    UniProtKB/TrEMBL
    A6IM48, D3ZGU3
    Conserved Domains (1) summary
    cd03593
    Location:136258
    CLECT_NK_receptors_like; C-type lectin-like domain (CTLD) of the type found in natural killer cell receptors (NKRs)
  3. XM_039108220.2XP_038964148.1  C-type lectin domain family 1 member A isoform X2

    Conserved Domains (1) summary
    cl02432
    Location:136180
    CLECT; C-type lectin (CTL)/C-type lectin-like (CTLD) domain