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Zscan20 zinc finger and SCAN domain containing 20 [ Rattus norvegicus (Norway rat) ]

Gene ID: 500549, updated on 11-Jul-2024

Summary

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Official Symbol
Zscan20provided by RGD
Official Full Name
zinc finger and SCAN domain containing 20provided by RGD
Primary source
RGD:1562996
See related
EnsemblRapid:ENSRNOG00000005886 AllianceGenome:RGD:1562996
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1562996
Summary
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Orthologous to human ZSCAN20 (zinc finger and SCAN domain containing 20). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Kidney (RPKM 31.6), Heart (RPKM 28.6) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Zscan20 in Genome Data Viewer
Location:
5q36
Exon count:
9
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 5 NC_086023.1 (146214023..146240678, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 5 NC_051340.1 (140926596..140956285, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 5 NC_005104.4 (146760822..146788945, complement)

Chromosome 5 - NC_086023.1Genomic Context describing neighboring genes Neighboring gene CUB and Sushi multiple domains 2 Neighboring gene high-mobility group box 4 Neighboring gene uncharacterized LOC134486995 Neighboring gene toll-like receptor 12 Neighboring gene polyhomeotic homolog 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
  
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
zinc finger and SCAN domain containing 20; zinc finger and SCAN domain-containing protein 20
Names
zinc finger and SCAN domains 20

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001431230.1 → NP_001418159.1  zinc finger and SCAN domain containing 20 isoform 1

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000005

  2. NM_001431231.1 → NP_001418160.1  zinc finger and SCAN domain containing 20 isoform 2

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000005

  3. NM_001431232.1 → NP_001418161.1  zinc finger and SCAN domain containing 20 isoform 3

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000005

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086023.1 Reference GRCr8

    Range
    146214023..146240678 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063288626.1 → XP_063144696.1  zinc finger and SCAN domain-containing protein 20 isoform X3

  2. XM_063288625.1 → XP_063144695.1  zinc finger and SCAN domain-containing protein 20 isoform X2

  3. XM_008764178.4 → XP_008762400.2  zinc finger and SCAN domain-containing protein 20 isoform X1

    Related
    ENSRNOP00000008887.7, ENSRNOT00000008887.8
    Conserved Domains (4) summary
    COG5048
    Location:818 → 1120
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:1042 → 1062
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam02023
    Location:136 → 221
    SCAN; SCAN domain
    pfam13837
    Location:410 → 491
    Myb_DNA-bind_4; Myb/SANT-like DNA-binding domain

  4. XM_063288627.1 → XP_063144697.1  zinc finger and SCAN domain-containing protein 20 isoform X4

    UniProtKB/TrEMBL
    D3ZCC2
    Related
    ENSRNOP00000099859.1, ENSRNOT00000157762.1

  5. XM_063288628.1 → XP_063144698.1  zinc finger and SCAN domain-containing protein 20 isoform X4

    UniProtKB/TrEMBL
    D3ZCC2
Nucleotide Protein Strain
Heading Accession and Version

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