Fam83a family with sequence similarity 83, member A [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Fam83aprovided by RGD
Official Full Name: family with sequence similarity 83, member Aprovided by RGD
Primary source: RGD:1565606
See related: EnsemblRapid:ENSRNOG00000006251 AllianceGenome:RGD:1565606
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: RGD1565606
Summary: Predicted to enable identical protein binding activity; phosphatidylinositol 3-kinase regulatory subunit binding activity; and protein kinase binding activity. Predicted to be involved in cell population proliferation and epidermal growth factor receptor signaling pathway. Orthologous to human FAM83A (family with sequence similarity 83 member A). [provided by Alliance of Genome Resources, Nov 2024]
Expression: Biased expression in Testes (RPKM 14.0) and Adrenal (RPKM 2.2) See more
Orthologs: human mouse all
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Genomic context

Location:: 7q33

Exon count:: 4

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	7	NC_086025.1 (91412366..91436819)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	7	NC_051342.1 (89522826..89547284)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	7	NC_005106.4 (97855773..97880227)

Chromosome 7 - NC_086025.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

LncRNA RMRP Contributes to the Development and Progression of Spinal Cord Injury by Regulating miR-766-5p/FAM83A Axis.
Title: LncRNA RMRP Contributes to the Development and Progression of Spinal Cord Injury by Regulating miR-766-5p/FAM83A Axis.

Submit: New GeneRIF Correction

General gene information

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Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables identical protein binding	ISO Inferred from Sequence Orthology more info
enables phosphatidylinositol 3-kinase regulatory subunit binding	ISO Inferred from Sequence Orthology more info
enables protein kinase binding	IBA Inferred from Biological aspect of Ancestor more info
enables protein kinase binding	ISO Inferred from Sequence Orthology more info

Process	Evidence Code	Pubs
involved_in cell population proliferation	ISO Inferred from Sequence Orthology more info
involved_in epidermal growth factor receptor signaling pathway	IBA Inferred from Biological aspect of Ancestor more info
involved_in epidermal growth factor receptor signaling pathway	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: protein FAM83A

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001130576.1 → NP_001124048.1 protein FAM83A

See identical proteins and their annotated locations for NP_001124048.1

Status: PROVISIONAL

Source sequence(s)

CH473950

UniProtKB/TrEMBL

A6HRI9, D3ZQN0

Related

ENSRNOP00000008330.4, ENSRNOT00000008330.7

Conserved Domains (1) summary

cd09181
Location:24 → 298

PLDc_FAM83A_N; N-terminal phospholipase D-like domain of the uncharacterized protein, Family with sequence similarity 83A