OTC - ornithine transcarbamylase
This nuclear gene encodes a mitochondrial matrix enzyme. The encoded protein is involved in the urea cycle which functions to detoxify ammonia into urea for excretion. Mutations in this enzyme lead to ornithine transcarbamylase deficiency, which causes hyperammonemia. [provided by RefSeq, May 2022]
NCBI Orthologs
How was this calculated?genes for:
Protein alignment
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Species | Gene | Architecture | aa |
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