Tpi1l1 triosephosphate isomerase 1 like 1 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Tpi1l1provided by RGD
Official Full Name: triosephosphate isomerase 1 like 1provided by RGD
Primary source: RGD:1560534
See related: EnsemblRapid:ENSRNOG00000055222 AllianceGenome:RGD:1560534
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary: Predicted to enable methylglyoxal synthase activity and triose-phosphate isomerase activity. Predicted to be involved in gluconeogenesis and glycolytic process. Human ortholog(s) of this gene implicated in carbohydrate metabolic disorder and triosephosphate isomerase deficiency. Orthologous to human TPI1 (triosephosphate isomerase 1). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

Location:: 8q13

Exon count:: 4

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	8	NC_086026.1 (31923596..31931244, complement)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	8	NC_051343.1 (23647760..23654967, complement)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	8	NC_005107.4 (26341789..26342573, complement)

Chromosome 8 - NC_086026.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables lyase activity	IEA Inferred from Electronic Annotation more info
enables methylglyoxal synthase activity	IEA Inferred from Electronic Annotation more info
enables triose-phosphate isomerase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in gluconeogenesis	IEA Inferred from Electronic Annotation more info
involved_in glycolytic process	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: triosephosphate isomerase 1 like 1

NP_001028244.1

EC 5.3.1.1

XP_038937855.1

EC 5.3.1.1

XP_063122032.1

EC 5.3.1.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001033072.1 → NP_001028244.1 triosephosphate isomerase 1 like 1

See identical proteins and their annotated locations for NP_001028244.1

Status: PROVISIONAL

Source sequence(s)

AY461585

UniProtKB/TrEMBL

A0A8L2R053, Q6SA19

Related

ENSRNOP00000105930.1, ENSRNOT00000149546.1

Conserved Domains (1) summary

PTZ00333
Location:2 → 247

PTZ00333; triosephosphate isomerase; Provisional

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

NC_086026.1 Reference GRCr8

Range

31923596..31931244 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_039081927.2 → XP_038937855.1 triosephosphate isomerase 1 like 1 isoform X1

UniProtKB/TrEMBL

A0A0G2JWU1, A0A8L2R053

Conserved Domains (1) summary

PTZ00333
Location:8 → 251

PTZ00333; triosephosphate isomerase; Provisional
XM_063265962.1 → XP_063122032.1 triosephosphate isomerase 1 like 1 isoform X1

UniProtKB/TrEMBL

A0A0G2JWU1