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Nxpe4 neurexophilin and PC-esterase domain family member 4 [ Rattus norvegicus (Norway rat) ]

Gene ID: 500991, updated on 2-Nov-2024

Summary

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Symbol
Nxpe4provided by RGD
Full Name
neurexophilin and PC-esterase domain family member 4provided by RGD
Primary source
RGD:1560781
See related
EnsemblRapid:ENSRNOG00000070472 AllianceGenome:RGD:1560781
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Fam55b; Fam55d
Summary
Predicted to be located in extracellular region. Orthologous to human NXPE4 (neurexophilin and PC-esterase domain family member 4). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Liver (RPKM 754.3), Spleen (RPKM 84.6) and 2 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Nxpe4 in Genome Data Viewer
Location:
8q23
Exon count:
12
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 8 NC_086026.1 (57399199..57640629)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 8 NC_051343.1 (48502697..48744101)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 8 NC_005107.4 (52717341..52734448)

Chromosome 8 - NC_086026.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC120094370 Neighboring gene uncharacterized LOC134480045 Neighboring gene neurexophilin and PC-esterase domain family, member 2 Neighboring gene neurexophilin and PC-esterase domain family, member 1 Neighboring gene RNA exonuclease 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT). Gonzalez-Begne M, et al. J Proteome Res, 2009 Mar. PMID 19199708, Free PMC Article
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334, Free PMC Article
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Component Evidence Code Pubs
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
NXPE family member 4
Names
family with sequence similarity 55, member B
protein FAM55D

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001025055.1 → NP_001020226.1  NXPE family member 4 precursor

    See identical proteins and their annotated locations for NP_001020226.1

    Status: PROVISIONAL

    Source sequence(s)
    BC083798
    UniProtKB/Swiss-Prot
    Q5XI89
    UniProtKB/TrEMBL
    A0A8I6AKA8
    Conserved Domains (1) summary
    pfam06312
    Location:127 → 255
    Neurexophilin

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086026.1 Reference GRCr8

    Range
    57399199..57640629
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039081953.2 → XP_038937881.1  NXPE family member 4 isoform X1

    UniProtKB/Swiss-Prot
    Q5XI89
    UniProtKB/TrEMBL
    A0A8I6AKA8
    Conserved Domains (1) summary
    pfam06312
    Location:127 → 255
    Neurexophilin

  2. XM_063265980.1 → XP_063122050.1  NXPE family member 4 isoform X1

    UniProtKB/Swiss-Prot
    Q5XI89

  3. XM_063265984.1 → XP_063122054.1  NXPE family member 4 isoform X1

    UniProtKB/Swiss-Prot
    Q5XI89

  4. XM_039081950.2 → XP_038937878.1  NXPE family member 4 isoform X1

    UniProtKB/Swiss-Prot
    Q5XI89
    UniProtKB/TrEMBL
    A0A8I6AKA8
    Related
    ENSRNOP00000077636.2, ENSRNOT00000093967.2
    Conserved Domains (1) summary
    pfam06312
    Location:127 → 255
    Neurexophilin

  5. XM_039081947.2 → XP_038937875.1  NXPE family member 4 isoform X1

    UniProtKB/Swiss-Prot
    Q5XI89
    UniProtKB/TrEMBL
    A0A8I6AKA8
    Conserved Domains (1) summary
    pfam06312
    Location:127 → 255
    Neurexophilin

  6. XM_039081951.2 → XP_038937879.1  NXPE family member 4 isoform X1

    UniProtKB/Swiss-Prot
    Q5XI89
    UniProtKB/TrEMBL
    A0A8I6AKA8
    Conserved Domains (1) summary
    pfam06312
    Location:127 → 255
    Neurexophilin

  7. XM_063265981.1 → XP_063122051.1  NXPE family member 4 isoform X1

    UniProtKB/Swiss-Prot
    Q5XI89

  8. XM_039081948.2 → XP_038937876.1  NXPE family member 4 isoform X1

    UniProtKB/Swiss-Prot
    Q5XI89
    UniProtKB/TrEMBL
    A0A8I6AKA8
    Conserved Domains (1) summary
    pfam06312
    Location:127 → 255
    Neurexophilin

  9. XM_063265983.1 → XP_063122053.1  NXPE family member 4 isoform X1

    UniProtKB/Swiss-Prot
    Q5XI89

  10. XM_063265978.1 → XP_063122048.1  NXPE family member 4 isoform X1

    UniProtKB/Swiss-Prot
    Q5XI89

  11. XM_063265982.1 → XP_063122052.1  NXPE family member 4 isoform X1

    UniProtKB/Swiss-Prot
    Q5XI89

  12. XM_063265977.1 → XP_063122047.1  NXPE family member 4 isoform X1

    UniProtKB/Swiss-Prot
    Q5XI89

  13. XM_039081952.2 → XP_038937880.1  NXPE family member 4 isoform X1

    UniProtKB/Swiss-Prot
    Q5XI89
    UniProtKB/TrEMBL
    A0A8I6AKA8
    Conserved Domains (1) summary
    pfam06312
    Location:127 → 255
    Neurexophilin

  14. XM_063265985.1 → XP_063122055.1  NXPE family member 4 isoform X2

Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q5XI89.1 GenPept UniProtKB/Swiss-Prot:Q5XI89

Gene LinkOut

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Chemical Information
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