U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Rpe ribulose-5-phosphate-3-epimerase [ Rattus norvegicus (Norway rat) ]

Gene ID: 501157, updated on 2-Nov-2024

Summary

Go to the top of the page Help
Official Symbol
Rpeprovided by RGD
Official Full Name
ribulose-5-phosphate-3-epimeraseprovided by RGD
Primary source
RGD:1564890
See related
EnsemblRapid:ENSRNOG00000038085 AllianceGenome:RGD:1564890
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Enables D-ribulose-phosphate 3-epimerase activity and monosaccharide binding activity. Involved in pentose-phosphate shunt, non-oxidative branch. Predicted to be active in cytosol. Orthologous to several human genes including RPE (ribulose-5-phosphate-3-epimerase). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Thymus (RPKM 189.4), Kidney (RPKM 160.6) and 9 other tissues See more
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See Rpe in Genome Data Viewer
Location:
9q32
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 9 NC_086027.1 (75640867..75661009)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 9 NC_051344.1 (68191027..68211295)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 9 NC_005108.4 (73687684..73713643)

Chromosome 9 - NC_086027.1Genomic Context describing neighboring genes Neighboring gene microtubule-associated protein 2 Neighboring gene unc-80 homolog, NALCN channel complex subunit Neighboring gene KAT8 regulatory NSL complex subunit 1-like Neighboring gene U7 small nuclear RNA Neighboring gene uncharacterized LOC134480586 Neighboring gene small nucleolar RNA SNORA17 Neighboring gene acyl-CoA dehydrogenase, long chain

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help
  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

Go to the top of the pageHelp

GeneRIFs: Gene References Into Functions

Pathways from PubChem

Go to the top of the page

General gene information

Go to the top of the page Help

Markers

Homology

Clone Names

  • MGC124653

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables D-ribulose-phosphate 3-epimerase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables D-ribulose-phosphate 3-epimerase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables D-ribulose-phosphate 3-epimerase activity ISO
Inferred from Sequence Orthology
more info
  
enables carbohydrate binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables identical protein binding ISO
Inferred from Sequence Orthology
more info
  
enables metal ion binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables metal ion binding ISO
Inferred from Sequence Orthology
more info
  
enables monosaccharide binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables protein homodimerization activity ISO
Inferred from Sequence Orthology
more info
  
Process Evidence Code Pubs
involved_in carbohydrate metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in carbohydrate metabolic process ISO
Inferred from Sequence Orthology
more info
  
involved_in pentose-phosphate shunt IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in pentose-phosphate shunt ISO
Inferred from Sequence Orthology
more info
  
involved_in pentose-phosphate shunt, non-oxidative branch IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in pentose-phosphate shunt, non-oxidative branch IDA
Inferred from Direct Assay
more info
 PubMed 
Component Evidence Code Pubs
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in cytosol ISO
Inferred from Sequence Orthology
more info
  

General protein information

Go to the top of the page Help
Preferred Names
ribulose-phosphate 3-epimerase
NP_001029075.1
NP_001386051.1
NP_001386052.1
NP_001386053.1
NP_001386054.1
NP_001386056.1
XP_006245167.1
XP_006245169.1
XP_008765509.1
XP_008765510.1
XP_008765511.1
XP_038940025.1
XP_063123688.1
XP_063123689.1
XP_063123690.1

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001033903.2 → NP_001029075.1  ribulose-phosphate 3-epimerase isoform 4

    See identical proteins and their annotated locations for NP_001029075.1

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000009
    UniProtKB/TrEMBL
    Q3MIF0
    Conserved Domains (1) summary
    cd00429
    Location:6 → 185
    RPE; Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose ...

  2. NM_001399122.1 → NP_001386051.1  ribulose-phosphate 3-epimerase isoform 1

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000009
    UniProtKB/TrEMBL
    A0A8I6GEB4
    Related
    ENSRNOP00000086710.1, ENSRNOT00000116351.2
    Conserved Domains (1) summary
    cd00429
    Location:6 → 245
    RPE; Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose ...

  3. NM_001399123.1 → NP_001386052.1  ribulose-phosphate 3-epimerase isoform 2

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000009
    Conserved Domains (1) summary
    cd00429
    Location:6 → 233
    RPE; Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose ...

  4. NM_001399124.1 → NP_001386053.1  ribulose-phosphate 3-epimerase isoform 3

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000009
    UniProtKB/TrEMBL
    A6KFD1
    Related
    ENSRNOP00000069730.3, ENSRNOT00000079495.3
    Conserved Domains (1) summary
    cd00429
    Location:6 → 214
    RPE; Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose ...

  5. NM_001399125.1 → NP_001386054.1  ribulose-phosphate 3-epimerase isoform 5

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000009
    Conserved Domains (1) summary
    cd00429
    Location:1 → 151
    RPE; Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose ...

  6. NM_001399127.1 → NP_001386056.1  ribulose-phosphate 3-epimerase isoform 6

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000009
    UniProtKB/TrEMBL
    A6KFD3
    Conserved Domains (1) summary
    cd00429
    Location:1 → 146
    RPE; Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose ...

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086027.1 Reference GRCr8

    Range
    75640867..75661009
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_008767288.4 → XP_008765510.1  ribulose-phosphate 3-epimerase isoform X3

    Conserved Domains (1) summary
    cd00429
    Location:6 → 221
    RPE; Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose ...

  2. XM_008767287.4 → XP_008765509.1  ribulose-phosphate 3-epimerase isoform X1

    Conserved Domains (1) summary
    cd00429
    Location:6 → 250
    RPE; Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose ...

  3. XM_006245105.5 → XP_006245167.1  ribulose-phosphate 3-epimerase isoform X2

    Conserved Domains (1) summary
    cd00429
    Location:6 → 238
    RPE; Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose ...

  4. XM_063267618.1 → XP_063123688.1  ribulose-phosphate 3-epimerase isoform X5

  5. XM_063267619.1 → XP_063123689.1  ribulose-phosphate 3-epimerase isoform X6

    Related
    ENSRNOP00000017197.6, ENSRNOT00000017197.9

  6. XM_006245107.5 → XP_006245169.1  ribulose-phosphate 3-epimerase isoform X4

    UniProtKB/TrEMBL
    A0A0G2JW38
    Conserved Domains (1) summary
    cd00429
    Location:6 → 219
    RPE; Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose ...

  7. XM_008767289.3 → XP_008765511.1  ribulose-phosphate 3-epimerase isoform X7

    Conserved Domains (1) summary
    cd00429
    Location:12 → 166
    RPE; Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose ...

  8. XM_063267620.1 → XP_063123690.1  ribulose-phosphate 3-epimerase isoform X8

  9. XM_039084097.2 → XP_038940025.1  ribulose-phosphate 3-epimerase isoform X7

    Conserved Domains (1) summary
    cd00429
    Location:12 → 166
    RPE; Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose ...
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Chemical Information
Molecular Biology Databases
Research Materials
Tools