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Serf2 small EDRK-rich factor 2 [ Rattus norvegicus (Norway rat) ]

Gene ID: 502663, updated on 2-Nov-2024

Summary

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Official Symbol
Serf2provided by RGD
Official Full Name
small EDRK-rich factor 2provided by RGD
Primary source
RGD:1588368
See related
EnsemblRapid:ENSRNOG00000064233 AllianceGenome:RGD:1588368
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to be involved in protein destabilization. Orthologous to human SERF2 (small EDRK-rich factor 2). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Heart (RPKM 868.4), Muscle (RPKM 604.3) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Serf2 in Genome Data Viewer
Location:
3q35
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 3 NC_086021.1 (128880681..128884457)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 3 NC_051338.1 (108426960..108430736)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 3 NC_005102.4 (113415757..113419417)

Chromosome 3 - NC_086021.1Genomic Context describing neighboring genes Neighboring gene protein disulfide isomerase family A, member 3 Neighboring gene U6 spliceosomal RNA Neighboring gene elongation factor for RNA polymerase II 3 Neighboring gene serine incorporator 4 Neighboring gene Huntingtin interacting protein K Neighboring gene microfibrillar-associated protein 1A

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Identification of MOAG-4/SERF as a regulator of age-related proteotoxicity. van Ham TJ, et al. Cell, 2010 Aug 20. PMID 20723760
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Process Evidence Code Pubs
involved_in protein destabilization ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
small EDRK-rich factor 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001098782.1 → NP_001092252.1  small EDRK-rich factor 2 isoform 2

    See identical proteins and their annotated locations for NP_001092252.1

    Status: VALIDATED

    Source sequence(s)
    BC081918
    Conserved Domains (1) summary
    pfam04419
    Location:1 → 37
    4F5; 4F5 protein family

  2. NM_001401909.1 → NP_001388838.1  small EDRK-rich factor 2 isoform 1

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000003
    Related
    ENSRNOP00000097402.2, ENSRNOT00000113737.2

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086021.1 Reference GRCr8

    Range
    128880681..128884457
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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