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Kbtbd12 kelch repeat and BTB domain containing 12 [ Rattus norvegicus (Norway rat) ]

Gene ID: 502859, updated on 2-Nov-2024

Summary

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Official Symbol
Kbtbd12provided by RGD
Official Full Name
kelch repeat and BTB domain containing 12provided by RGD
Primary source
RGD:1585999
See related
EnsemblRapid:ENSRNOG00000061868 AllianceGenome:RGD:1585999
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Orthologous to human KBTBD12 (kelch repeat and BTB domain containing 12). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Muscle (RPKM 207.9) and Heart (RPKM 93.7) See more
Orthologs
human mouse all
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Genomic context

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See Kbtbd12 in Genome Data Viewer
Location:
4q34
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 4 NC_086022.1 (122571903..122645895, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 4 NC_051339.1 (121014636..121088701, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 4 NC_005103.4 (120492541..120567755, complement)

Chromosome 4 - NC_086022.1Genomic Context describing neighboring genes Neighboring gene ribosomal protein S25 like 3 Neighboring gene RuvB-like AAA ATPase 1 Neighboring gene SEC61 translocon subunit alpha 1 Neighboring gene uncharacterized LOC134486810 Neighboring gene transfer RNA valine (anticodon AAC) 19 Neighboring gene monoglyceride lipase

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

General protein information

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Preferred Names
kelch repeat and BTB domain containing 12; kelch repeat and BTB domain-containing protein 12
Names
kelch repeat and BTB (POZ) domain containing 12

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001431870.1 → NP_001418799.1  kelch repeat and BTB domain containing 12

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000004
    UniProtKB/TrEMBL
    D3ZQ37

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086022.1 Reference GRCr8

    Range
    122571903..122645895 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_003749799.6 → XP_003749847.1  kelch repeat and BTB domain-containing protein 12 isoform X1

    Related
    ENSRNOP00000069816.2, ENSRNOT00000079575.3
    Conserved Domains (6) summary
    smart00612
    Location:437 → 491
    Kelch; Kelch domain
    PHA03098
    Location:29 → 586
    PHA03098; kelch-like protein; Provisional
    sd00038
    Location:375 → 422
    Kelch; KELCH repeat [structural motif]
    pfam00651
    Location:26 → 124
    BTB; BTB/POZ domain
    pfam01344
    Location:483 → 534
    Kelch_1; Kelch motif
    pfam07707
    Location:133 → 235
    BACK; BTB And C-terminal Kelch

  2. XM_039108733.2 → XP_038964661.1  kelch repeat and BTB domain-containing protein 12 isoform X2

    UniProtKB/TrEMBL
    A0A0G2K982
    Conserved Domains (4) summary
    PHA03098
    Location:29 → 561
    PHA03098; kelch-like protein; Provisional
    sd00038
    Location:375 → 422
    Kelch; KELCH repeat [structural motif]
    cd18485
    Location:128 → 226
    BACK_KBTBD12; BACK (BTB and C-terminal Kelch) domain found in Kelch repeat and BTB domain-containing protein 12 (KBTBD12)
    cl38908
    Location:10 → 136
    BTB_POZ; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain superfamily
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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