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Mrps7 mitchondrial ribosomal protein S7 [ Mus musculus (house mouse) ]

Gene ID: 50529, updated on 28-Oct-2024

Summary

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Official Symbol
Mrps7provided by MGI
Official Full Name
mitchondrial ribosomal protein S7provided by MGI
Primary source
MGI:MGI:1354367
See related
Ensembl:ENSMUSG00000046756 AllianceGenome:MGI:1354367
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
S7mt; Rpms7; MRP-S7
Summary
Predicted to enable mRNA binding activity and rRNA binding activity. Predicted to be a structural constituent of ribosome. Predicted to be involved in mitochondrial translation and ribosomal small subunit assembly. Located in mitochondrion. Is expressed in several structures, including early conceptus; gonad; heart; liver; and metanephros. Human ortholog(s) of this gene implicated in combined oxidative phosphorylation deficiency 34. Orthologous to human MRPS7 (mitochondrial ribosomal protein S7). [provided by Alliance of Genome Resources, Oct 2024]
Expression
Ubiquitous expression in placenta adult (RPKM 28.7), kidney adult (RPKM 24.2) and 28 other tissues See more
Orthologs
human all
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Genomic context

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See Mrps7 in Genome Data Viewer
Location:
11 E2; 11 80.9 cM
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (115494966..115498862)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (115604140..115608036)

Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene nucleoporin 85 Neighboring gene golgi associated, gamma adaptin ear containing, ARF binding protein 3 Neighboring gene STARR-seq mESC enhancer starr_31165 Neighboring gene predicted gene, 25364 Neighboring gene STARR-positive B cell enhancer ABC_E7096 Neighboring gene MIF4G domain containing Neighboring gene solute carrier family 25 (mitochondrial thiamine pyrophosphate carrier), member 19 Neighboring gene STARR-seq mESC enhancer starr_31166 Neighboring gene STARR-positive B cell enhancer mm9_chr11:115494169-115494470 Neighboring gene STARR-positive B cell enhancer ABC_E8470 Neighboring gene STARR-positive B cell enhancer ABC_E2375 Neighboring gene growth factor receptor bound protein 2 Neighboring gene STARR-positive B cell enhancer ABC_E10730 Neighboring gene STARR-positive B cell enhancer ABC_E7098

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Identification of a mammalian mitochondrial homolog of ribosomal protein S7. Cavdar Koc E, et al. Biochem Biophys Res Commun, 1999 Dec 9. PMID 10581179
  2. DYRK1a mediates BAFF-induced noncanonical NF-κB activation to promote autoimmunity and B-cell leukemogenesis. Li Y, et al. Blood, 2021 Dec 9. PMID 34255829, Free PMC Article
  3. Ribosome. The structure of the human mitochondrial ribosome. Amunts A, et al. Science, 2015 Apr 3. PMID 25838379, Free PMC Article
  4. Expression analysis of mammalian mitochondrial ribosomal protein genes. Cheong A, et al. Gene Expr Patterns, 2020 Dec. PMID 32987154, Free PMC Article
  5. Structure and Function of the Mitochondrial Ribosome. Greber BJ, et al. Annu Rev Biochem, 2016 Jun 2. PMID 27023846

See all (29) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables mRNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables rRNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables structural constituent of ribosome IBA
Inferred from Biological aspect of Ancestor
more info
  
enables structural constituent of ribosome ISA
Inferred from Sequence Alignment
more info
 PubMed 
enables structural constituent of ribosome ISS
Inferred from Sequence or Structural Similarity
more info
  
Process Evidence Code Pubs
involved_in mitochondrial translation ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in mitochondrial translation NAS
Non-traceable Author Statement
more info
 PubMed 
involved_in ribosomal small subunit assembly IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in translation IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within translation ISA
Inferred from Sequence Alignment
more info
 PubMed 
Component Evidence Code Pubs
located_in mitochondrial inner membrane NAS
Non-traceable Author Statement
more info
 PubMed 
part_of mitochondrial small ribosomal subunit IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of mitochondrial small ribosomal subunit ISA
Inferred from Sequence Alignment
more info
 PubMed 
part_of mitochondrial small ribosomal subunit ISO
Inferred from Sequence Orthology
more info
  
part_of mitochondrial small ribosomal subunit ISS
Inferred from Sequence or Structural Similarity
more info
  
part_of mitochondrial small ribosomal subunit NAS
Non-traceable Author Statement
more info
 PubMed 
located_in mitochondrion HDA PubMed 
is_active_in ribosome IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
small ribosomal subunit protein uS7m
Names
28S ribosomal protein S7, mitochondrial
ribosomal protein, mitochondrial, S7
NP_079581.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_025305.3 → NP_079581.1  small ribosomal subunit protein uS7m precursor

    See identical proteins and their annotated locations for NP_079581.1

    Status: VALIDATED

    Source sequence(s)
    AK131937, AK162024
    Consensus CDS
    CCDS25642.1
    UniProtKB/Swiss-Prot
    Q3TSI9, Q80X85, Q9CV71
    Related
    ENSMUSP00000053033.9, ENSMUST00000058109.9
    Conserved Domains (1) summary
    cd14870
    Location:35 → 240
    uS7_Mitochondria_Mammalian; Mammalian Mitochondrial homolog of Ribosomal Protein S7

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000077.7 Reference GRCm39 C57BL/6J

    Range
    115494966..115498862
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q80X85.1 GenPept UniProtKB/Swiss-Prot:Q80X85

Gene LinkOut

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