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PAM peptidylglycine alpha-amidating monooxygenase [ Homo sapiens (human) ]

Gene ID: 5066, updated on 2-Nov-2024

Summary

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Official Symbol
PAMprovided by HGNC
Official Full Name
peptidylglycine alpha-amidating monooxygenaseprovided by HGNC
Primary source
HGNC:HGNC:8596
See related
Ensembl:ENSG00000145730 MIM:170270; AllianceGenome:HGNC:8596
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
PAL; PHM; PAM-1
Summary
This gene encodes a multifunctional protein. The encoded preproprotein is proteolytically processed to generate the mature enzyme. This enzyme includes two domains with distinct catalytic activities, a peptidylglycine alpha-hydroxylating monooxygenase (PHM) domain and a peptidyl-alpha-hydroxyglycine alpha-amidating lyase (PAL) domain. These catalytic domains work sequentially to catalyze the conversion of neuroendocrine peptides to active alpha-amidated products. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Jan 2016]
Expression
Broad expression in heart (RPKM 269.6), adrenal (RPKM 54.3) and 15 other tissues See more
Orthologs
mouse all
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Genomic context

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See PAM in Genome Data Viewer
Location:
5q21.1
Exon count:
29
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 5 NC_000005.10 (102754783..103031105)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 5 NC_060929.1 (103262795..103539139)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 5 NC_000005.9 (102090487..102366809)

Chromosome 5 - NC_000005.10Genomic Context describing neighboring genes Neighboring gene long intergenic non-protein coding RNA 492 Neighboring gene long intergenic non-protein coding RNA 491 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr5:101996845-101997345 Neighboring gene VISTA enhancer hs1649 Neighboring gene uncharacterized LOC105379104 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 16207 Neighboring gene NANOG hESC enhancer GRCh37_chr5:102085276-102085842 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr5:102090038-102090563 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 16208 Neighboring gene H3K27ac hESC enhancer GRCh37_chr5:102091571-102092071 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 22856 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 16209 Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr5:102363594-102364793 Neighboring gene Sharpr-MPRA regulatory region 7406 Neighboring gene uncharacterized LOC105379105 Neighboring gene eukaryotic translation initiation factor 3 subunit K pseudogene 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: HPA RNA-seq normal tissues HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

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Related articles in PubMed

  1. Use of endoproteases to identify catalytic domains, linker regions, and functional interactions in soluble peptidylglycine alpha-amidating monooxygenase. Husten EJ, et al. J Biol Chem, 1993 May 5. PMID 8486658
  2. Production of the catalytic core of human peptidylglycine α-hydroxylating monooxygenase (hPHMcc) in Escherichia coli. Handa S, et al. Protein Expr Purif, 2012 Jul. PMID 22554821, Free PMC Article
  3. A copper-methionine interaction controls the pH-dependent activation of peptidylglycine monooxygenase. Bauman AT, et al. Biochemistry, 2011 Dec 20. PMID 22080626, Free PMC Article
  4. The peptidylglycine alpha-amidating monooxygenase (PAM): a novel prodrug strategy for amidoximes and N-hydroxyguanidines? Schade D, et al. ChemMedChem, 2009 Oct. PMID 19693765
  5. Immunocytochemical finding of the amidating enzymes in mouse pancreatic A-, B-, and D-cells: a comparison with human and rat. Garmendia O, et al. J Histochem Cytochem, 2002 Oct. PMID 12364573

See all (64) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. PAM variants in patients with thyrotrophinomas, cyclical Cushing's disease and prolactinomas.
    Title: PAM variants in patients with thyrotrophinomas, cyclical Cushing's disease and prolactinomas.
  2. Peptidylglycine alpha-amidating monooxygenase and adrenomedullin measurement in patients with hepatic cirrhosis.
    Title: Peptidylglycine α-amidating monooxygenase and adrenomedullin measurement in patients with hepatic cirrhosis.
  3. PAM variants were associated with type 2 diabetes mellitus risk in the Chinese population.
    Title: PAM variants were associated with type 2 diabetes mellitus risk in the Chinese population.
  4. The T2D risk-associated rs35658696 (p.Asp563Gly) allele of PAM confers decreased PAM expression in human islets.
    Title: Type 2 diabetes risk alleles in PAM impact insulin release from human pancreatic β-cells.
  5. siRNA-mediated knockdown of PAM in EndoC-BetaH1 cells caused reductions in insulin secretion and content. These effects were also observed in primary islets from human donors heterozygous for the T2D risk-associated rs35658696 variant.
    Title: Type 2 diabetes risk alleles in PAM impact insulin release from human pancreatic β-cells.
  6. The T2D risk-associated rs35658696 (p.Asp563Gly) allele of PAM confers reduced amidating activity.
    Title: Type 2 diabetes risk alleles in PAM impact insulin release from human pancreatic β-cells.
  7. PAM haploinsufficiency does not accelerate the development of diet- and human IAPP-induced diabetes in mice.
    Title: PAM haploinsufficiency does not accelerate the development of diet- and human IAPP-induced diabetes in mice.
  8. Mitochondrial Oxidative Stress Induces Rapid Intermembrane Space/Matrix Translocation of Apurinic/Apyrimidinic Endonuclease 1 Protein through TIM23 Complex.
    Title: Mitochondrial Oxidative Stress Induces Rapid Intermembrane Space/Matrix Translocation of Apurinic/Apyrimidinic Endonuclease 1 Protein through TIM23 Complex.
  9. A role for PAM in beta-cell function.
    Title: Type 2 diabetes risk alleles in PAM impact insulin release from human pancreatic β-cells.
  10. PAM polyubiquitinates NMNAT2 and regulates NMNAT2 protein stability and degradation by the proteasome.
    Title: PAM forms an atypical SCF ubiquitin ligase complex that ubiquitinates and degrades NMNAT2.
Submit: New GeneRIF Correction See all GeneRIFs (21)

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Genotypes

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables L-ascorbic acid binding IEA
Inferred from Electronic Annotation
more info
  
enables calcium ion binding ISS
Inferred from Sequence or Structural Similarity
more info
  
enables copper ion binding ISS
Inferred from Sequence or Structural Similarity
more info
  
enables peptidylamidoglycolate lyase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables peptidylamidoglycolate lyase activity ISS
Inferred from Sequence or Structural Similarity
more info
  
enables peptidylglycine monooxygenase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables peptidylglycine monooxygenase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
  
enables zinc ion binding IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
involved_in fatty acid primary amide biosynthetic process ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in peptide amidation IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in response to zinc ion IDA
Inferred from Direct Assay
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular exosome HDA PubMed 
is_active_in extracellular region IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in membrane HDA PubMed 
located_in secretory granule membrane ISS
Inferred from Sequence or Structural Similarity
more info
  
located_in transport vesicle membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
peptidyl-glycine alpha-amidating monooxygenase
Names
pancreatic peptidylglycine alpha-amidating monooxygenase
peptidyl alpha-amidating enzyme
peptidyl-alpha-hydroxyglycine alpha-amidating lyase
peptidylamidoglycolate lyase
peptidylglycine 2-hydroxylase
peptidylglycine alpha-hydroxylating monooxygenase
NP_000910.2
NP_001170777.1
NP_001306872.1
NP_001351511.1
NP_001351512.1
NP_001351513.1
NP_001351514.1
NP_001351515.1
NP_001351516.1
NP_001351517.1
NP_001351518.1
NP_001351519.1
NP_001351520.1
NP_001351521.1
NP_001351522.1
NP_001351523.1
NP_620121.1
NP_620176.1
NP_620177.1
XP_011541721.1
XP_016864984.1
XP_016864985.1
XP_016864986.1
XP_016864991.1
XP_016864994.1
XP_016864996.1
XP_016865000.1
XP_024301834.1
XP_024301837.1
XP_024301838.1
XP_024301840.1
XP_024301842.1
XP_024301843.1
XP_024301844.1
XP_024301846.1
XP_024301848.1
XP_024301849.1
XP_024301852.1
XP_024301853.1
XP_047273196.1
XP_047273197.1
XP_047273198.1
XP_047273199.1
XP_047273200.1
XP_047273201.1
XP_047273202.1
XP_047273203.1
XP_047273204.1
XP_047273205.1
XP_047273206.1
XP_047273207.1
XP_047273208.1
XP_047273209.1
XP_047273210.1
XP_047273211.1
XP_047273212.1
XP_054208643.1
XP_054208644.1
XP_054208645.1
XP_054208646.1
XP_054208647.1
XP_054208648.1
XP_054208649.1
XP_054208650.1
XP_054208651.1
XP_054208652.1
XP_054208653.1
XP_054208654.1
XP_054208655.1
XP_054208656.1
XP_054208657.1
XP_054208658.1
XP_054208659.1
XP_054208660.1
XP_054208661.1
XP_054208662.1
XP_054208663.1
XP_054208664.1
XP_054208665.1
XP_054208666.1
XP_054208667.1
XP_054208668.1
XP_054208669.1
XP_054208670.1
XP_054208671.1
XP_054208672.1
XP_054208673.1
XP_054208674.1
XP_054208675.1
XP_054208676.1
XP_054208677.1
XP_054208678.1
XP_054208679.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_029444.2 RefSeqGene

    Range
    5523..279934
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_000919.4 → NP_000910.2  peptidyl-glycine alpha-amidating monooxygenase isoform a precursor

    See identical proteins and their annotated locations for NP_000910.2

    Status: REVIEWED

    Description
    Transcript Variant: This variant (1) uses an alternate in-frame splice site in the 3' coding region compared to variant 5. The encoded isoform (a) is longer than isoform e. This isoform (a) may undergo proteolytic processing similar to isoform e.
    Source sequence(s)
    AC008501, AC008779, AC010250, AC113373
    Consensus CDS
    CCDS43348.1
    UniProtKB/TrEMBL
    A0A804HI59
    Related
    ENSP00000507038.1, ENST00000684529.1
    Conserved Domains (3) summary
    cd14958
    Location:500 → 807
    NHL_PAL_like; Peptidyl-alpha-hydroxyglycine alpha-amidating lyase (PAL, EC 4.3.2.5)
    pfam01082
    Location:59 → 168
    Cu2_monooxygen; Copper type II ascorbate-dependent monooxygenase, N-terminal domain
    pfam03712
    Location:196 → 342
    Cu2_monoox_C; Copper type II ascorbate-dependent monooxygenase, C-terminal domain

  2. NM_001177306.2 → NP_001170777.1  peptidyl-glycine alpha-amidating monooxygenase isoform e preproprotein

    See identical proteins and their annotated locations for NP_001170777.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (5) encodes isoform e.
    Source sequence(s)
    AC008501, AC008779, AC010250, AC113373
    Consensus CDS
    CCDS54885.1
    UniProtKB/Swiss-Prot
    A6NMR0, A8K293, O43211, O95080, P19021, Q16252, Q16253, Q54A45, Q86U53, Q8WVC7, Q9UCG0
    UniProtKB/TrEMBL
    A0A804HI59
    Related
    ENSP00000396493.3, ENST00000438793.8
    Conserved Domains (3) summary
    cd14958
    Location:500 → 807
    NHL_PAL_like; Peptidyl-alpha-hydroxyglycine alpha-amidating lyase (PAL, EC 4.3.2.5)
    pfam01082
    Location:59 → 168
    Cu2_monooxygen; Copper type II ascorbate-dependent monooxygenase, N-terminal domain
    pfam03712
    Location:196 → 342
    Cu2_monoox_C; Copper type II ascorbate-dependent monooxygenase, C-terminal domain

  3. NM_001319943.1 → NP_001306872.1  peptidyl-glycine alpha-amidating monooxygenase isoform f precursor

    Status: REVIEWED

    Description
    Transcript Variant: This variant (7) differs in the 5' UTR and contains an alternate in-frame exon in its central coding region compared to variant 5. The encoded isoform (f) is longer than isoform e and may undergo proteolytic processing similar to isoform e.
    Source sequence(s)
    AB095007, AC010250, BI966687, DA240822, DA406933, U19966
    UniProtKB/TrEMBL
    A0A804HI59
    Conserved Domains (3) summary
    cd14958
    Location:518 → 825
    NHL_PAL_like; Peptidyl-alpha-hydroxyglycine alpha-amidating lyase (PAL, EC 4.3.2.5)
    pfam01082
    Location:59 → 168
    Cu2_monooxygen; Copper type II ascorbate-dependent monooxygenase, N-terminal domain
    pfam03712
    Location:196 → 342
    Cu2_monoox_C; Copper type II ascorbate-dependent monooxygenase, C-terminal domain

  4. NM_001364582.2 → NP_001351511.1  peptidyl-glycine alpha-amidating monooxygenase isoform g precursor

    Status: REVIEWED

    Source sequence(s)
    AC008779, AC010250, AC113373
    Consensus CDS
    CCDS93753.1
    UniProtKB/TrEMBL
    A0A804HI59
    Related
    ENSP00000506966.1, ENST00000682407.1
    Conserved Domains (3) summary
    cd14958
    Location:500 → 807
    NHL_PAL_like; Peptidyl-alpha-hydroxyglycine alpha-amidating lyase (PAL, EC 4.3.2.5)
    pfam01082
    Location:59 → 168
    Cu2_monooxygen; Copper type II ascorbate-dependent monooxygenase, N-terminal domain
    pfam03712
    Location:196 → 342
    Cu2_monoox_C; Copper type II ascorbate-dependent monooxygenase, C-terminal domain

  5. NM_001364583.2 → NP_001351512.1  peptidyl-glycine alpha-amidating monooxygenase isoform h precursor

    Status: REVIEWED

    Source sequence(s)
    AC008501, AC008779, AC010250, AC113373
    Consensus CDS
    CCDS93754.1
    UniProtKB/TrEMBL
    A0A804HI59, A0A8C8KD64
    Related
    ENSP00000306100.8, ENST00000304400.12
    Conserved Domains (3) summary
    cd14958
    Location:500 → 807
    NHL_PAL_like; Peptidyl-alpha-hydroxyglycine alpha-amidating lyase (PAL, EC 4.3.2.5)
    pfam01082
    Location:59 → 168
    Cu2_monooxygen; Copper type II ascorbate-dependent monooxygenase, N-terminal domain
    pfam03712
    Location:196 → 342
    Cu2_monoox_C; Copper type II ascorbate-dependent monooxygenase, C-terminal domain

  6. NM_001364584.2 → NP_001351513.1  peptidyl-glycine alpha-amidating monooxygenase isoform i precursor

    Status: REVIEWED

    Source sequence(s)
    AC008501, AC008779, AC010250, AC113373
    UniProtKB/TrEMBL
    A0A804HI59
    Conserved Domains (3) summary
    cd14958
    Location:500 → 807
    NHL_PAL_like; Peptidyl-alpha-hydroxyglycine alpha-amidating lyase (PAL, EC 4.3.2.5)
    pfam01082
    Location:59 → 168
    Cu2_monooxygen; Copper type II ascorbate-dependent monooxygenase, N-terminal domain
    pfam03712
    Location:196 → 342
    Cu2_monoox_C; Copper type II ascorbate-dependent monooxygenase, C-terminal domain

  7. NM_001364585.2 → NP_001351514.1  peptidyl-glycine alpha-amidating monooxygenase isoform j precursor

    Status: REVIEWED

    Source sequence(s)
    AC008501, AC008779, AC010250, AC113373
    UniProtKB/TrEMBL
    A0A804HI59
    Conserved Domains (3) summary
    cd14958
    Location:500 → 807
    NHL_PAL_like; Peptidyl-alpha-hydroxyglycine alpha-amidating lyase (PAL, EC 4.3.2.5)
    pfam01082
    Location:59 → 168
    Cu2_monooxygen; Copper type II ascorbate-dependent monooxygenase, N-terminal domain
    pfam03712
    Location:196 → 342
    Cu2_monoox_C; Copper type II ascorbate-dependent monooxygenase, C-terminal domain

  8. NM_001364586.2 → NP_001351515.1  peptidyl-glycine alpha-amidating monooxygenase isoform k precursor

    Status: REVIEWED

    Source sequence(s)
    AC008501, AC008779, AC010250, AC113373
    Consensus CDS
    CCDS93755.1
    UniProtKB/TrEMBL
    A0A804HI59, A0A804HIQ0
    Related
    ENSP00000507172.1, ENST00000682972.1
    Conserved Domains (3) summary
    cd14958
    Location:393 → 700
    NHL_PAL_like; Peptidyl-alpha-hydroxyglycine alpha-amidating lyase (PAL, EC 4.3.2.5)
    pfam01082
    Location:59 → 168
    Cu2_monooxygen; Copper type II ascorbate-dependent monooxygenase, N-terminal domain
    pfam03712
    Location:196 → 342
    Cu2_monoox_C; Copper type II ascorbate-dependent monooxygenase, C-terminal domain

  9. NM_001364587.2 → NP_001351516.1  peptidyl-glycine alpha-amidating monooxygenase isoform l precursor

    Status: REVIEWED

    Source sequence(s)
    AC008501, AC008779, AC010250, AC113373
    UniProtKB/TrEMBL
    A0A804HI59
    Conserved Domains (3) summary
    cd14958
    Location:393 → 700
    NHL_PAL_like; Peptidyl-alpha-hydroxyglycine alpha-amidating lyase (PAL, EC 4.3.2.5)
    pfam01082
    Location:59 → 168
    Cu2_monooxygen; Copper type II ascorbate-dependent monooxygenase, N-terminal domain
    pfam03712
    Location:196 → 342
    Cu2_monoox_C; Copper type II ascorbate-dependent monooxygenase, C-terminal domain

  10. NM_001364588.2 → NP_001351517.1  peptidyl-glycine alpha-amidating monooxygenase isoform m precursor

    Status: REVIEWED

    Source sequence(s)
    AC008501, AC008779, AC010250, AC113373
    UniProtKB/TrEMBL
    A0A804HI59
    Conserved Domains (3) summary
    cd14958
    Location:393 → 700
    NHL_PAL_like; Peptidyl-alpha-hydroxyglycine alpha-amidating lyase (PAL, EC 4.3.2.5)
    pfam01082
    Location:59 → 168
    Cu2_monooxygen; Copper type II ascorbate-dependent monooxygenase, N-terminal domain
    pfam03712
    Location:196 → 342
    Cu2_monoox_C; Copper type II ascorbate-dependent monooxygenase, C-terminal domain

  11. NM_001364589.2 → NP_001351518.1  peptidyl-glycine alpha-amidating monooxygenase isoform n precursor

    Status: REVIEWED

    Source sequence(s)
    AC008501, AC008779, AC010250, AC113373
    UniProtKB/TrEMBL
    A0A804HI59
    Conserved Domains (3) summary
    cd14958
    Location:393 → 700
    NHL_PAL_like; Peptidyl-alpha-hydroxyglycine alpha-amidating lyase (PAL, EC 4.3.2.5)
    pfam01082
    Location:59 → 168
    Cu2_monooxygen; Copper type II ascorbate-dependent monooxygenase, N-terminal domain
    pfam03712
    Location:196 → 342
    Cu2_monoox_C; Copper type II ascorbate-dependent monooxygenase, C-terminal domain

  12. NM_001364590.2 → NP_001351519.1  peptidyl-glycine alpha-amidating monooxygenase isoform o

    Status: REVIEWED

    Source sequence(s)
    AC008501, AC008779, AC010250, AC113373
    Consensus CDS
    CCDS93757.1
    UniProtKB/TrEMBL
    A0A804HI59, A0A804HKM7
    Related
    ENSP00000507990.1, ENST00000682882.1
    Conserved Domains (3) summary
    cd14958
    Location:424 → 731
    NHL_PAL_like; Peptidyl-alpha-hydroxyglycine alpha-amidating lyase (PAL, EC 4.3.2.5)
    pfam01082
    Location:3 → 92
    Cu2_monooxygen; Copper type II ascorbate-dependent monooxygenase, N-terminal domain
    pfam03712
    Location:120 → 266
    Cu2_monoox_C; Copper type II ascorbate-dependent monooxygenase, C-terminal domain

  13. NM_001364591.2 → NP_001351520.1  peptidyl-glycine alpha-amidating monooxygenase isoform p precursor

    Status: REVIEWED

    Source sequence(s)
    AC008501, AC008779, AC010250, AC113373
    UniProtKB/TrEMBL
    A0A804HI59
    Conserved Domains (3) summary
    cd14958
    Location:411 → 718
    NHL_PAL_like; Peptidyl-alpha-hydroxyglycine alpha-amidating lyase (PAL, EC 4.3.2.5)
    pfam01082
    Location:59 → 168
    Cu2_monooxygen; Copper type II ascorbate-dependent monooxygenase, N-terminal domain
    pfam03712
    Location:196 → 342
    Cu2_monoox_C; Copper type II ascorbate-dependent monooxygenase, C-terminal domain

  14. NM_001364592.2 → NP_001351521.1  peptidyl-glycine alpha-amidating monooxygenase isoform q precursor

    Status: REVIEWED

    Source sequence(s)
    AC008501, AC008779, AC010250, AC113373
    UniProtKB/TrEMBL
    A0A804HI59
    Conserved Domains (3) summary
    cd14958
    Location:411 → 718
    NHL_PAL_like; Peptidyl-alpha-hydroxyglycine alpha-amidating lyase (PAL, EC 4.3.2.5)
    pfam01082
    Location:59 → 168
    Cu2_monooxygen; Copper type II ascorbate-dependent monooxygenase, N-terminal domain
    pfam03712
    Location:196 → 342
    Cu2_monoox_C; Copper type II ascorbate-dependent monooxygenase, C-terminal domain

  15. NM_001364593.2 → NP_001351522.1  peptidyl-glycine alpha-amidating monooxygenase isoform r precursor

    Status: REVIEWED

    Source sequence(s)
    AC008501, AC008779, AC010250, AC113373
    UniProtKB/TrEMBL
    A0A804HI59
    Conserved Domains (3) summary
    cd14958
    Location:393 → 700
    NHL_PAL_like; Peptidyl-alpha-hydroxyglycine alpha-amidating lyase (PAL, EC 4.3.2.5)
    pfam01082
    Location:59 → 168
    Cu2_monooxygen; Copper type II ascorbate-dependent monooxygenase, N-terminal domain
    pfam03712
    Location:196 → 342
    Cu2_monoox_C; Copper type II ascorbate-dependent monooxygenase, C-terminal domain

  16. NM_001364594.2 → NP_001351523.1  peptidyl-glycine alpha-amidating monooxygenase isoform s precursor

    Status: REVIEWED

    Source sequence(s)
    AC008501, AC008779, AC010250, AC113373
    Consensus CDS
    CCDS93756.1
    UniProtKB/TrEMBL
    A0A804HI59, A0A804HKV8
    Related
    ENSP00000508091.1, ENST00000510208.2
    Conserved Domains (3) summary
    cd14958
    Location:393 → 700
    NHL_PAL_like; Peptidyl-alpha-hydroxyglycine alpha-amidating lyase (PAL, EC 4.3.2.5)
    pfam01082
    Location:59 → 168
    Cu2_monooxygen; Copper type II ascorbate-dependent monooxygenase, N-terminal domain
    pfam03712
    Location:196 → 342
    Cu2_monoox_C; Copper type II ascorbate-dependent monooxygenase, C-terminal domain

  17. NM_138766.2 → NP_620121.1  peptidyl-glycine alpha-amidating monooxygenase isoform b precursor

    See identical proteins and their annotated locations for NP_620121.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (2, also known as PAM-15) lacks an alternate in-frame exon in the 3' coding region compared to variant 5. The encoded isoform (b) is shorter than isoform e. This isoform (b) may undergo proteolytic processing similar to isoform e.
    Source sequence(s)
    AC010250, BI966687, DA240822, S75038
    Consensus CDS
    CCDS4092.1
    UniProtKB/TrEMBL
    A0A804HI59
    Conserved Domains (3) summary
    cd14958
    Location:500 → 807
    NHL_PAL_like; Peptidyl-alpha-hydroxyglycine alpha-amidating lyase (PAL, EC 4.3.2.5)
    pfam01082
    Location:59 → 168
    Cu2_monooxygen; Copper type II ascorbate-dependent monooxygenase, N-terminal domain
    pfam03712
    Location:196 → 342
    Cu2_monoox_C; Copper type II ascorbate-dependent monooxygenase, C-terminal domain

  18. NM_138821.2 → NP_620176.1  peptidyl-glycine alpha-amidating monooxygenase isoform c precursor

    See identical proteins and their annotated locations for NP_620176.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (3) lacks an alternate in-frame exon in the 5' coding region compared to variant 5. The encoded isoform (c) is shorter than isoform e. This isoform (c) may undergo proteolytic processing similar to isoform e.
    Source sequence(s)
    AC010250, BI966687, BT007419, DA240822
    Consensus CDS
    CCDS4093.1
    UniProtKB/TrEMBL
    A0A804HI59
    Conserved Domains (3) summary
    cd14958
    Location:393 → 700
    NHL_PAL_like; Peptidyl-alpha-hydroxyglycine alpha-amidating lyase (PAL, EC 4.3.2.5)
    pfam01082
    Location:59 → 168
    Cu2_monooxygen; Copper type II ascorbate-dependent monooxygenase, N-terminal domain
    pfam03712
    Location:196 → 342
    Cu2_monoox_C; Copper type II ascorbate-dependent monooxygenase, C-terminal domain

  19. NM_138822.2 → NP_620177.1  peptidyl-glycine alpha-amidating monooxygenase isoform d precursor

    See identical proteins and their annotated locations for NP_620177.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (4) lacks two alternate in-frame exons in the 3' coding region compared to variant 5. The encoded isoform (d) is shorter than isoform e. This isoform (d) may undergo proteolytic processing similar to isoform e.
    Source sequence(s)
    AC010250, AF010472, BI966687, DA240822
    Consensus CDS
    CCDS4094.1
    UniProtKB/TrEMBL
    A0A804HI59
    Related
    ENSP00000282992.3, ENST00000346918.7
    Conserved Domains (3) summary
    cd14958
    Location:500 → 807
    NHL_PAL_like; Peptidyl-alpha-hydroxyglycine alpha-amidating lyase (PAL, EC 4.3.2.5)
    pfam01082
    Location:59 → 168
    Cu2_monooxygen; Copper type II ascorbate-dependent monooxygenase, N-terminal domain
    pfam03712
    Location:196 → 342
    Cu2_monoox_C; Copper type II ascorbate-dependent monooxygenase, C-terminal domain

RNA

  1. NR_033440.1 RNA Sequence

    Status: REVIEWED

    Description
    Transcript Variant: This variant (6) lacks an alternate internal exon in the 5' region and uses two alternate splice sites in the 3' region, compared to variant 1. This variant is represented as non-coding because the use of the supported translational start codon, as used in variant 1, renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
    Source sequence(s)
    AC010250, AC113373, AK296521, BI966687, DA240822

  2. NR_157231.1 RNA Sequence

    Status: REVIEWED

    Source sequence(s)
    AC008501, AC008779, AC113373

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000005.10 Reference GRCh38.p14 Primary Assembly

    Range
    102754783..103031105
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_024446066.2 → XP_024301834.1  peptidyl-glycine alpha-amidating monooxygenase isoform X1

    UniProtKB/TrEMBL
    A0A804HI59
    Conserved Domains (3) summary
    cd14958
    Location:518 → 825
    NHL_PAL_like; Peptidyl-alpha-hydroxyglycine alpha-amidating lyase (PAL, EC 4.3.2.5)
    pfam01082
    Location:59 → 168
    Cu2_monooxygen; Copper type II ascorbate-dependent monooxygenase, N-terminal domain
    pfam03712
    Location:196 → 342
    Cu2_monoox_C; Copper type II ascorbate-dependent monooxygenase, C-terminal domain

  2. XM_024446069.2 → XP_024301837.1  peptidyl-glycine alpha-amidating monooxygenase isoform X6

    UniProtKB/TrEMBL
    A0A804HI59
    Conserved Domains (3) summary
    cd14958
    Location:518 → 825
    NHL_PAL_like; Peptidyl-alpha-hydroxyglycine alpha-amidating lyase (PAL, EC 4.3.2.5)
    pfam01082
    Location:59 → 168
    Cu2_monooxygen; Copper type II ascorbate-dependent monooxygenase, N-terminal domain
    pfam03712
    Location:196 → 342
    Cu2_monoox_C; Copper type II ascorbate-dependent monooxygenase, C-terminal domain

  3. XM_017009495.3 → XP_016864984.1  peptidyl-glycine alpha-amidating monooxygenase isoform X2

    UniProtKB/TrEMBL
    A0A804HI59
    Conserved Domains (3) summary
    cd14958
    Location:518 → 825
    NHL_PAL_like; Peptidyl-alpha-hydroxyglycine alpha-amidating lyase (PAL, EC 4.3.2.5)
    pfam01082
    Location:59 → 168
    Cu2_monooxygen; Copper type II ascorbate-dependent monooxygenase, N-terminal domain
    pfam03712
    Location:196 → 342
    Cu2_monoox_C; Copper type II ascorbate-dependent monooxygenase, C-terminal domain

  4. XM_017009496.3 → XP_016864985.1  peptidyl-glycine alpha-amidating monooxygenase isoform X3

    UniProtKB/TrEMBL
    A0A804HI59
    Conserved Domains (3) summary
    cd14958
    Location:518 → 825
    NHL_PAL_like; Peptidyl-alpha-hydroxyglycine alpha-amidating lyase (PAL, EC 4.3.2.5)
    pfam01082
    Location:59 → 168
    Cu2_monooxygen; Copper type II ascorbate-dependent monooxygenase, N-terminal domain
    pfam03712
    Location:196 → 342
    Cu2_monoox_C; Copper type II ascorbate-dependent monooxygenase, C-terminal domain

  5. XM_047417241.1 → XP_047273197.1  peptidyl-glycine alpha-amidating monooxygenase isoform X7

  6. XM_017009502.3 → XP_016864991.1  peptidyl-glycine alpha-amidating monooxygenase isoform X10

    UniProtKB/TrEMBL
    A0A804HI59
    Conserved Domains (3) summary
    cd14958
    Location:518 → 825
    NHL_PAL_like; Peptidyl-alpha-hydroxyglycine alpha-amidating lyase (PAL, EC 4.3.2.5)
    pfam01082
    Location:59 → 168
    Cu2_monooxygen; Copper type II ascorbate-dependent monooxygenase, N-terminal domain
    pfam03712
    Location:196 → 342
    Cu2_monoox_C; Copper type II ascorbate-dependent monooxygenase, C-terminal domain

  7. XM_024446072.2 → XP_024301840.1  peptidyl-glycine alpha-amidating monooxygenase isoform X11

    UniProtKB/TrEMBL
    A0A804HI59
    Conserved Domains (3) summary
    cd14958
    Location:518 → 825
    NHL_PAL_like; Peptidyl-alpha-hydroxyglycine alpha-amidating lyase (PAL, EC 4.3.2.5)
    pfam01082
    Location:59 → 168
    Cu2_monooxygen; Copper type II ascorbate-dependent monooxygenase, N-terminal domain
    pfam03712
    Location:196 → 342
    Cu2_monoox_C; Copper type II ascorbate-dependent monooxygenase, C-terminal domain

  8. XM_024446075.2 → XP_024301843.1  peptidyl-glycine alpha-amidating monooxygenase isoform X14

    UniProtKB/TrEMBL
    A0A804HI59
    Conserved Domains (3) summary
    cd14958
    Location:518 → 825
    NHL_PAL_like; Peptidyl-alpha-hydroxyglycine alpha-amidating lyase (PAL, EC 4.3.2.5)
    pfam01082
    Location:59 → 168
    Cu2_monooxygen; Copper type II ascorbate-dependent monooxygenase, N-terminal domain
    pfam03712
    Location:196 → 342
    Cu2_monoox_C; Copper type II ascorbate-dependent monooxygenase, C-terminal domain

  9. XM_017009511.3 → XP_016865000.1  peptidyl-glycine alpha-amidating monooxygenase isoform X21

    Conserved Domains (3) summary
    cd14958
    Location:518 → 795
    NHL_PAL_like; Peptidyl-alpha-hydroxyglycine alpha-amidating lyase (PAL, EC 4.3.2.5)
    pfam01082
    Location:59 → 168
    Cu2_monooxygen; Copper type II ascorbate-dependent monooxygenase, N-terminal domain
    pfam03712
    Location:196 → 342
    Cu2_monoox_C; Copper type II ascorbate-dependent monooxygenase, C-terminal domain

  10. XM_024446080.2 → XP_024301848.1  peptidyl-glycine alpha-amidating monooxygenase isoform X22

    Conserved Domains (3) summary
    cd14958
    Location:518 → 795
    NHL_PAL_like; Peptidyl-alpha-hydroxyglycine alpha-amidating lyase (PAL, EC 4.3.2.5)
    pfam01082
    Location:59 → 168
    Cu2_monooxygen; Copper type II ascorbate-dependent monooxygenase, N-terminal domain
    pfam03712
    Location:196 → 342
    Cu2_monoox_C; Copper type II ascorbate-dependent monooxygenase, C-terminal domain

  11. XM_024446081.2 → XP_024301849.1  peptidyl-glycine alpha-amidating monooxygenase isoform X26

    Conserved Domains (3) summary
    cd14958
    Location:518 → 795
    NHL_PAL_like; Peptidyl-alpha-hydroxyglycine alpha-amidating lyase (PAL, EC 4.3.2.5)
    pfam01082
    Location:59 → 168
    Cu2_monooxygen; Copper type II ascorbate-dependent monooxygenase, N-terminal domain
    pfam03712
    Location:196 → 342
    Cu2_monoox_C; Copper type II ascorbate-dependent monooxygenase, C-terminal domain

  12. XM_024446070.2 → XP_024301838.1  peptidyl-glycine alpha-amidating monooxygenase isoform X8

    UniProtKB/TrEMBL
    A0A804HI59
    Conserved Domains (3) summary
    cd14958
    Location:500 → 807
    NHL_PAL_like; Peptidyl-alpha-hydroxyglycine alpha-amidating lyase (PAL, EC 4.3.2.5)
    pfam01082
    Location:59 → 168
    Cu2_monooxygen; Copper type II ascorbate-dependent monooxygenase, N-terminal domain
    pfam03712
    Location:196 → 342
    Cu2_monoox_C; Copper type II ascorbate-dependent monooxygenase, C-terminal domain

  13. XM_047417242.1 → XP_047273198.1  peptidyl-glycine alpha-amidating monooxygenase isoform X9

  14. XM_024446074.2 → XP_024301842.1  peptidyl-glycine alpha-amidating monooxygenase isoform X13

    UniProtKB/TrEMBL
    A0A804HI59
    Related
    ENSP00000403461.2, ENST00000455264.7
    Conserved Domains (3) summary
    cd14958
    Location:500 → 807
    NHL_PAL_like; Peptidyl-alpha-hydroxyglycine alpha-amidating lyase (PAL, EC 4.3.2.5)
    pfam01082
    Location:59 → 168
    Cu2_monooxygen; Copper type II ascorbate-dependent monooxygenase, N-terminal domain
    pfam03712
    Location:196 → 342
    Cu2_monoox_C; Copper type II ascorbate-dependent monooxygenase, C-terminal domain

  15. XM_024446076.2 → XP_024301844.1  peptidyl-glycine alpha-amidating monooxygenase isoform X15

    UniProtKB/TrEMBL
    A0A804HI59
    Conserved Domains (3) summary
    cd14958
    Location:500 → 807
    NHL_PAL_like; Peptidyl-alpha-hydroxyglycine alpha-amidating lyase (PAL, EC 4.3.2.5)
    pfam01082
    Location:59 → 168
    Cu2_monooxygen; Copper type II ascorbate-dependent monooxygenase, N-terminal domain
    pfam03712
    Location:196 → 342
    Cu2_monoox_C; Copper type II ascorbate-dependent monooxygenase, C-terminal domain

  16. XM_047417249.1 → XP_047273205.1  peptidyl-glycine alpha-amidating monooxygenase isoform X24

  17. XM_047417250.1 → XP_047273206.1  peptidyl-glycine alpha-amidating monooxygenase isoform X25

  18. XM_047417251.1 → XP_047273207.1  peptidyl-glycine alpha-amidating monooxygenase isoform X27

  19. XM_024446078.2 → XP_024301846.1  peptidyl-glycine alpha-amidating monooxygenase isoform X17

    UniProtKB/TrEMBL
    A0A804HI59
    Related
    ENSP00000314638.3, ENST00000348126.7
    Conserved Domains (3) summary
    cd14958
    Location:393 → 700
    NHL_PAL_like; Peptidyl-alpha-hydroxyglycine alpha-amidating lyase (PAL, EC 4.3.2.5)
    pfam01082
    Location:59 → 168
    Cu2_monooxygen; Copper type II ascorbate-dependent monooxygenase, N-terminal domain
    pfam03712
    Location:196 → 342
    Cu2_monoox_C; Copper type II ascorbate-dependent monooxygenase, C-terminal domain

  20. XM_047417245.1 → XP_047273201.1  peptidyl-glycine alpha-amidating monooxygenase isoform X18

  21. XM_024446084.2 → XP_024301852.1  peptidyl-glycine alpha-amidating monooxygenase isoform X29

    Conserved Domains (3) summary
    cd14958
    Location:393 → 700
    NHL_PAL_like; Peptidyl-alpha-hydroxyglycine alpha-amidating lyase (PAL, EC 4.3.2.5)
    pfam01082
    Location:59 → 168
    Cu2_monooxygen; Copper type II ascorbate-dependent monooxygenase, N-terminal domain
    pfam03712
    Location:196 → 342
    Cu2_monoox_C; Copper type II ascorbate-dependent monooxygenase, C-terminal domain

  22. XM_047417254.1 → XP_047273210.1  peptidyl-glycine alpha-amidating monooxygenase isoform X32

  23. XM_047417255.1 → XP_047273211.1  peptidyl-glycine alpha-amidating monooxygenase isoform X33

  24. XM_047417256.1 → XP_047273212.1  peptidyl-glycine alpha-amidating monooxygenase isoform X34

  25. XM_047417246.1 → XP_047273202.1  peptidyl-glycine alpha-amidating monooxygenase isoform X19

  26. XM_047417247.1 → XP_047273203.1  peptidyl-glycine alpha-amidating monooxygenase isoform X20

  27. XM_047417253.1 → XP_047273209.1  peptidyl-glycine alpha-amidating monooxygenase isoform X31

  28. XM_011543419.4 → XP_011541721.1  peptidyl-glycine alpha-amidating monooxygenase isoform X1

    See identical proteins and their annotated locations for XP_011541721.1

    UniProtKB/TrEMBL
    A0A804HI59
    Conserved Domains (3) summary
    cd14958
    Location:518 → 825
    NHL_PAL_like; Peptidyl-alpha-hydroxyglycine alpha-amidating lyase (PAL, EC 4.3.2.5)
    pfam01082
    Location:59 → 168
    Cu2_monooxygen; Copper type II ascorbate-dependent monooxygenase, N-terminal domain
    pfam03712
    Location:196 → 342
    Cu2_monoox_C; Copper type II ascorbate-dependent monooxygenase, C-terminal domain

  29. XM_017009497.3 → XP_016864986.1  peptidyl-glycine alpha-amidating monooxygenase isoform X4

    UniProtKB/TrEMBL
    A0A804HI59
    Conserved Domains (3) summary
    cd14958
    Location:500 → 807
    NHL_PAL_like; Peptidyl-alpha-hydroxyglycine alpha-amidating lyase (PAL, EC 4.3.2.5)
    pfam01082
    Location:59 → 168
    Cu2_monooxygen; Copper type II ascorbate-dependent monooxygenase, N-terminal domain
    pfam03712
    Location:196 → 342
    Cu2_monoox_C; Copper type II ascorbate-dependent monooxygenase, C-terminal domain

  30. XM_047417240.1 → XP_047273196.1  peptidyl-glycine alpha-amidating monooxygenase isoform X5

    UniProtKB/Swiss-Prot
    A6NMR0, A8K293, O43211, O95080, P19021, Q16252, Q16253, Q54A45, Q86U53, Q8WVC7, Q9UCG0

  31. XM_047417243.1 → XP_047273199.1  peptidyl-glycine alpha-amidating monooxygenase isoform X12

  32. XM_017009505.3 → XP_016864994.1  peptidyl-glycine alpha-amidating monooxygenase isoform X13

    UniProtKB/TrEMBL
    A0A804HI59
    Conserved Domains (3) summary
    cd14958
    Location:500 → 807
    NHL_PAL_like; Peptidyl-alpha-hydroxyglycine alpha-amidating lyase (PAL, EC 4.3.2.5)
    pfam01082
    Location:59 → 168
    Cu2_monooxygen; Copper type II ascorbate-dependent monooxygenase, N-terminal domain
    pfam03712
    Location:196 → 342
    Cu2_monoox_C; Copper type II ascorbate-dependent monooxygenase, C-terminal domain

  33. XM_017009507.3 → XP_016864996.1  peptidyl-glycine alpha-amidating monooxygenase isoform X16

    UniProtKB/TrEMBL
    A0A804HI59, A0A804HIQ0
    Conserved Domains (3) summary
    cd14958
    Location:393 → 700
    NHL_PAL_like; Peptidyl-alpha-hydroxyglycine alpha-amidating lyase (PAL, EC 4.3.2.5)
    pfam01082
    Location:59 → 168
    Cu2_monooxygen; Copper type II ascorbate-dependent monooxygenase, N-terminal domain
    pfam03712
    Location:196 → 342
    Cu2_monoox_C; Copper type II ascorbate-dependent monooxygenase, C-terminal domain

  34. XM_047417244.1 → XP_047273200.1  peptidyl-glycine alpha-amidating monooxygenase isoform X17

  35. XM_024446085.2 → XP_024301853.1  peptidyl-glycine alpha-amidating monooxygenase isoform X30

    UniProtKB/TrEMBL
    A0A804HI59
    Conserved Domains (3) summary
    cd14958
    Location:442 → 749
    NHL_PAL_like; Peptidyl-alpha-hydroxyglycine alpha-amidating lyase (PAL, EC 4.3.2.5)
    pfam01082
    Location:3 → 92
    Cu2_monooxygen; Copper type II ascorbate-dependent monooxygenase, N-terminal domain
    pfam03712
    Location:120 → 266
    Cu2_monoox_C; Copper type II ascorbate-dependent monooxygenase, C-terminal domain

  36. XM_047417248.1 → XP_047273204.1  peptidyl-glycine alpha-amidating monooxygenase isoform X23

    Related
    ENSP00000369125.3, ENST00000379799.7

  37. XM_047417252.1 → XP_047273208.1  peptidyl-glycine alpha-amidating monooxygenase isoform X28

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060929.1 Alternate T2T-CHM13v2.0

    Range
    103262795..103539139
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054352668.1 → XP_054208643.1  peptidyl-glycine alpha-amidating monooxygenase isoform X1

  2. XM_054352674.1 → XP_054208649.1  peptidyl-glycine alpha-amidating monooxygenase isoform X6

  3. XM_054352670.1 → XP_054208645.1  peptidyl-glycine alpha-amidating monooxygenase isoform X2

  4. XM_054352671.1 → XP_054208646.1  peptidyl-glycine alpha-amidating monooxygenase isoform X3

  5. XM_054352675.1 → XP_054208650.1  peptidyl-glycine alpha-amidating monooxygenase isoform X7

  6. XM_054352678.1 → XP_054208653.1  peptidyl-glycine alpha-amidating monooxygenase isoform X10

  7. XM_054352679.1 → XP_054208654.1  peptidyl-glycine alpha-amidating monooxygenase isoform X11

  8. XM_054352683.1 → XP_054208658.1  peptidyl-glycine alpha-amidating monooxygenase isoform X14

  9. XM_054352691.1 → XP_054208666.1  peptidyl-glycine alpha-amidating monooxygenase isoform X21

  10. XM_054352692.1 → XP_054208667.1  peptidyl-glycine alpha-amidating monooxygenase isoform X22

  11. XM_054352696.1 → XP_054208671.1  peptidyl-glycine alpha-amidating monooxygenase isoform X26

  12. XM_054352676.1 → XP_054208651.1  peptidyl-glycine alpha-amidating monooxygenase isoform X8

  13. XM_054352677.1 → XP_054208652.1  peptidyl-glycine alpha-amidating monooxygenase isoform X9

  14. XM_054352681.1 → XP_054208656.1  peptidyl-glycine alpha-amidating monooxygenase isoform X13

  15. XM_054352684.1 → XP_054208659.1  peptidyl-glycine alpha-amidating monooxygenase isoform X15

  16. XM_054352694.1 → XP_054208669.1  peptidyl-glycine alpha-amidating monooxygenase isoform X24

  17. XM_054352695.1 → XP_054208670.1  peptidyl-glycine alpha-amidating monooxygenase isoform X25

  18. XM_054352697.1 → XP_054208672.1  peptidyl-glycine alpha-amidating monooxygenase isoform X27

  19. XM_054352686.1 → XP_054208661.1  peptidyl-glycine alpha-amidating monooxygenase isoform X17

  20. XM_054352688.1 → XP_054208663.1  peptidyl-glycine alpha-amidating monooxygenase isoform X18

  21. XM_054352699.1 → XP_054208674.1  peptidyl-glycine alpha-amidating monooxygenase isoform X29

  22. XM_054352702.1 → XP_054208677.1  peptidyl-glycine alpha-amidating monooxygenase isoform X32

  23. XM_054352703.1 → XP_054208678.1  peptidyl-glycine alpha-amidating monooxygenase isoform X33

  24. XM_054352704.1 → XP_054208679.1  peptidyl-glycine alpha-amidating monooxygenase isoform X34

  25. XM_054352689.1 → XP_054208664.1  peptidyl-glycine alpha-amidating monooxygenase isoform X19

  26. XM_054352690.1 → XP_054208665.1  peptidyl-glycine alpha-amidating monooxygenase isoform X20

  27. XM_054352701.1 → XP_054208676.1  peptidyl-glycine alpha-amidating monooxygenase isoform X31

  28. XM_054352669.1 → XP_054208644.1  peptidyl-glycine alpha-amidating monooxygenase isoform X1

  29. XM_054352672.1 → XP_054208647.1  peptidyl-glycine alpha-amidating monooxygenase isoform X4

  30. XM_054352673.1 → XP_054208648.1  peptidyl-glycine alpha-amidating monooxygenase isoform X5

    UniProtKB/Swiss-Prot
    A6NMR0, A8K293, O43211, O95080, P19021, Q16252, Q16253, Q54A45, Q86U53, Q8WVC7, Q9UCG0

  31. XM_054352680.1 → XP_054208655.1  peptidyl-glycine alpha-amidating monooxygenase isoform X12

  32. XM_054352682.1 → XP_054208657.1  peptidyl-glycine alpha-amidating monooxygenase isoform X13

  33. XM_054352685.1 → XP_054208660.1  peptidyl-glycine alpha-amidating monooxygenase isoform X16

    UniProtKB/TrEMBL
    A0A804HIQ0

  34. XM_054352687.1 → XP_054208662.1  peptidyl-glycine alpha-amidating monooxygenase isoform X17

  35. XM_054352700.1 → XP_054208675.1  peptidyl-glycine alpha-amidating monooxygenase isoform X30

  36. XM_054352693.1 → XP_054208668.1  peptidyl-glycine alpha-amidating monooxygenase isoform X23

  37. XM_054352698.1 → XP_054208673.1  peptidyl-glycine alpha-amidating monooxygenase isoform X28

Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P19021.2 GenPept UniProtKB/Swiss-Prot:P19021

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