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Sh3bgr SH3-binding domain glutamic acid-rich protein [ Mus musculus (house mouse) ]

Gene ID: 50795, updated on 2-Nov-2024

Summary

Official Symbol
Sh3bgrprovided by MGI
Official Full Name
SH3-binding domain glutamic acid-rich proteinprovided by MGI
Primary source
MGI:MGI:1354740
See related
Ensembl:ENSMUSG00000040666 AllianceGenome:MGI:1354740
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
5430437A18Rik
Summary
Predicted to enable SH3 domain binding activity. Predicted to be active in cytoplasm. Is expressed in several structures, including alimentary system; brain; cardiovascular system; genitourinary system; and sensory organ. Orthologous to human SH3BGR (SH3 domain binding glutamate rich protein). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in bladder adult (RPKM 40.7), heart adult (RPKM 35.7) and 8 other tissues See more
Orthologs
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Genomic context

See Sh3bgr in Genome Data Viewer
Location:
16 C4; 16 56.86 cM
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 16 NC_000082.7 (96001670..96030133)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 16 NC_000082.6 (96200470..96228933)

Chromosome 16 - NC_000082.7Genomic Context describing neighboring genes Neighboring gene guided entry of tail-anchored proteins factor 1 Neighboring gene Leber congenital amaurosis 5-like Neighboring gene predicted gene, 53923 Neighboring gene STARR-positive B cell enhancer ABC_E7483 Neighboring gene STARR-seq mESC enhancer starr_41616 Neighboring gene UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 5 Neighboring gene CapStarr-seq enhancer MGSCv37_chr16:96495129-96495238 Neighboring gene CapStarr-seq enhancer MGSCv37_chr16:96514185-96514338 Neighboring gene STARR-positive B cell enhancer mm9_chr16:96562962-96563262 Neighboring gene predicted gene, 41510

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

General gene information

Markers

Potential readthrough

Included gene: Get1

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables SH3 domain binding IEA
Inferred from Electronic Annotation
more info
 
enables molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
 
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
SH3 domain-binding glutamic acid-rich protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_015825.2NP_056640.1  SH3 domain-binding glutamic acid-rich protein

    See identical proteins and their annotated locations for NP_056640.1

    Status: VALIDATED

    Source sequence(s)
    AC164647, AC165170
    Consensus CDS
    CCDS28355.1
    UniProtKB/Swiss-Prot
    Q9WUZ7
    UniProtKB/TrEMBL
    Q8R558
    Related
    ENSMUSP00000038110.9, ENSMUST00000048770.16
    Conserved Domains (1) summary
    pfam04908
    Location:198
    SH3BGR; SH3-binding, glutamic acid-rich protein

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000082.7 Reference GRCm39 C57BL/6J

    Range
    96001670..96030133
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)