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PTGIR prostaglandin I2 receptor [ Bos taurus (domestic cattle) ]

Gene ID: 520278, updated on 4-Oct-2024

Summary

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Official Symbol
PTGIRprovided by VGNC
Official Full Name
prostaglandin I2 receptorprovided by VGNC
Primary source
VGNC:VGNC:49149
See related
BGD:BT22332; Ensembl:ENSBTAG00000014585
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs
human mouse all
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Genomic context

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See PTGIR in Genome Data Viewer
Location:
chromosome: 18
Exon count:
2
Annotation release Status Assembly Chr Location
RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 18 NC_037345.1 (53746036..53756538, complement)

Chromosome 18 - NC_037345.1Genomic Context describing neighboring genes Neighboring gene transfer RNA alanine (anticodon AGC) Neighboring gene uncharacterized LOC132342869 Neighboring gene calmodulin 3 Neighboring gene G protein subunit gamma 8 Neighboring gene dishevelled binding antagonist of beta catenin 3

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_037345.1 Chromosome 18 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables prostacyclin receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in adenylate cyclase-activating G protein-coupled receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in inflammatory response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of smooth muscle cell proliferation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of cytosolic calcium ion concentration IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
prostacyclin receptor
Names
PGI receptor
PGI2 receptor
prostaglandin I2 (prostacyclin) receptor (IP)
prostanoid IP receptor

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001015622.2 → NP_001015622.2  prostacyclin receptor

    See identical proteins and their annotated locations for NP_001015622.2

    Status: PROVISIONAL

    Source sequence(s)
    NKLS02000018
    UniProtKB/Swiss-Prot
    P79393
    Conserved Domains (2) summary
    pfam00001
    Location:30 → 292
    7tm_1; 7 transmembrane receptor (rhodopsin family)
    cl21561
    Location:27 → 221
    7tm_4; Olfactory receptor

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037345.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    53746036..53756538 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005219278.5 → XP_005219335.1  prostacyclin receptor isoform X1

    See identical proteins and their annotated locations for XP_005219335.1

    UniProtKB/Swiss-Prot
    P79393
    UniProtKB/TrEMBL
    E1BQ27
    Related
    ENSBTAP00000019413.4, ENSBTAT00000019413.5
    Conserved Domains (2) summary
    cd14964
    Location:16 → 40
    7tm_GPCRs; TM helix 1 [structural motif]
    cl28897
    Location:14 → 303
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P79393.1 GenPept UniProtKB/Swiss-Prot:P79393

Gene LinkOut

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