FZD7 frizzled class receptor 7 [Bos taurus (domestic cattle)] - Gene

Summary

Official Symbol: FZD7provided by VGNC
Official Full Name: frizzled class receptor 7provided by VGNC
Primary source: VGNC:VGNC:29171
See related: BGD:BT13986; Ensembl:ENSBTAG00000002283
Gene type: protein coding
RefSeq status: INFERRED
Organism: Bos taurus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 2

Exon count:: 1

Annotation release	Status	Assembly	Chr	Location
RS_2023_09	current	ARS-UCD2.0 (GCF_002263795.3)	2	NC_037329.1 (90571270..90573476)

Chromosome 2 - NC_037329.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_037329.1 Chromosome 2 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

A missense mutation in the FZD7 gene is associated with dilution of the red areas of the coat in Montbeliarde cattle.
Title: A missense mutation in the FZD7 gene is associated with dilution of the red areas of the coat in Montbéliarde cattle.
Chimpanzee FZD7 and cow Fzd7 genes were identified and characterized.
Title: Comparative integromics on FZD7 orthologs: conserved binding sites for PU.1, SP1, CCAAT-box and TCF/LEF/SOX transcription factors within 5'-promoter region of mammalian FZD7 orthologs.

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General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables Wnt receptor activity	IEA Inferred from Electronic Annotation more info	PubMed
enables Wnt-protein binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in canonical Wnt signaling pathway	IEA Inferred from Electronic Annotation more info	PubMed
involved_in non-canonical Wnt signaling pathway	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in plasma membrane	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: frizzled-7

Names: frizzled 7, seven transmembrane spanning receptor; frizzled family receptor 7; frizzled homolog 7

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001144091.1 → NP_001137563.1 frizzled-7 precursor

See identical proteins and their annotated locations for NP_001137563.1

Status: INFERRED

Source sequence(s)

NKLS02000002

UniProtKB/TrEMBL

F1N4K7

Related

ENSBTAP00000002946.5, ENSBTAT00000002946.7

Conserved Domains (2) summary

cd07466
Location:45 → 167

CRD_FZ7; Cysteine-rich Wnt-binding domain (CRD) of the frizzled 7 (Fz7) receptor

cd15246
Location:243 → 573

7tmF_FZD7; class F frizzled subfamily 7, member of 7-transmembrane G protein-coupled receptors