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polr1h RNA polymerase I subunit H [ Danio rerio (zebrafish) ]

Gene ID: 541428, updated on 12-Sep-2024

Summary

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Official Symbol
polr1hprovided by ZNC
Official Full Name
RNA polymerase I subunit Hprovided by ZNC
Primary source
ZFIN:ZDB-GENE-050320-131
See related
Ensembl:ENSDARG00000036070 AllianceGenome:ZFIN:ZDB-GENE-050320-131
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
znrd1; zgc:110825
Summary
Predicted to enable nucleic acid binding activity and zinc ion binding activity. Predicted to contribute to DNA-directed 5'-3' RNA polymerase activity. Predicted to be involved in termination of RNA polymerase I transcription. Predicted to act upstream of or within mRNA cleavage and transcription, DNA-templated. Predicted to be located in nucleus. Predicted to be part of RNA polymerase I complex. Orthologous to human POLR1H (RNA polymerase I subunit H). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
human mouse all
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Genomic context

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See polr1h in Genome Data Viewer
Location:
chromosome: 19
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 19 NC_007130.7 (27334527..27339847, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 19 NC_007130.6 (27750304..27755644, complement)

Chromosome 19 - NC_007130.7Genomic Context describing neighboring genes Neighboring gene SH3-binding domain protein 5-like, b Neighboring gene general transcription factor IIH, polypeptide 4 Neighboring gene DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B Neighboring gene alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase b

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables DNA-directed 5'-3' RNA polymerase activity IEA
Inferred from Electronic Annotation
more info
  
contributes_to RNA polymerase I activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables nucleic acid binding IEA
Inferred from Electronic Annotation
more info
  
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
  
involved_in termination of RNA polymerase I transcription IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
part_of DNA-directed RNA polymerase complex IEA
Inferred from Electronic Annotation
more info
  
part_of RNA polymerase I complex IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
DNA-directed RNA polymerase I subunit RPA12
Names
zinc ribbon domain containing 1
NP_001013572.1
XP_005170088.1
XP_068071227.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001013554.2 → NP_001013572.1  DNA-directed RNA polymerase I subunit RPA12

    See identical proteins and their annotated locations for NP_001013572.1

    Status: PROVISIONAL

    Source sequence(s)
    BC090545
    UniProtKB/TrEMBL
    Q5BL98
    Related
    ENSDARP00000052357.4, ENSDART00000052358.6
    Conserved Domains (2) summary
    COG1594
    Location:10 → 117
    RPB9; DNA-directed RNA polymerase, subunit M/Transcription elongation factor TFIIS [Transcription]
    cd10507
    Location:71 → 117
    Zn-ribbon_RPA12; C-terminal zinc ribbon domain of RPA12 subunit of RNA polymerase I

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007130.7 Reference GRCz11 Primary Assembly

    Range
    27334527..27339847 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005170031.3 → XP_005170088.1  DNA-directed RNA polymerase I subunit RPA12 isoform X1

    See identical proteins and their annotated locations for XP_005170088.1

    UniProtKB/TrEMBL
    A3KQ05, Q1LWR1
    Related
    ENSDARP00000121924.1, ENSDART00000137346.2
    Conserved Domains (2) summary
    COG1594
    Location:10 → 117
    RPB9; DNA-directed RNA polymerase, subunit M/Transcription elongation factor TFIIS [Transcription]
    cd10507
    Location:71 → 117
    Zn-ribbon_RPA12; C-terminal zinc ribbon domain of RPA12 subunit of RNA polymerase I

  2. XM_068215126.1 → XP_068071227.1  DNA-directed RNA polymerase I subunit RPA12 isoform X1

    Related
    ENSDARP00000115440.1, ENSDART00000148238.3
Nucleotide Protein Strain
Heading Accession and Version

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