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CCHCR1 coiled-coil alpha-helical rod protein 1 [ Homo sapiens (human) ]

Gene ID: 54535, updated on 2-Nov-2024

Summary

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Official Symbol
CCHCR1provided by HGNC
Official Full Name
coiled-coil alpha-helical rod protein 1provided by HGNC
Primary source
HGNC:HGNC:13930
See related
Ensembl:ENSG00000204536 MIM:605310; AllianceGenome:HGNC:13930
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
HCR; SBP; pg8; C6orf18
Summary
This gene encodes a protein with five coiled-coil alpha-helical rod domains that is thought to act as a regulator of mRNA metabolism through its interaction with mRNA-decapping protein 4. It localizes to P-bodies, the site of mRNA metabolism, with an N-terminus that is required for this subcellular localization, suggesting it is a P-body component. Naturally occurring mutations in this gene are associated with psoriasis. [provided by RefSeq, May 2017]
Annotation information
Note: This gene has been reviewed for its involvement in coronavirus biology, and is locus in the vicinity of disease-associated variant(s).
Expression
Broad expression in testis (RPKM 37.2), prostate (RPKM 4.5) and 18 other tissues See more
Orthologs
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Genomic context

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See CCHCR1 in Genome Data Viewer
Location:
6p21.33
Exon count:
19
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 6 NC_000006.12 (31142439..31158197, complement)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 6 NC_060930.1 (31010125..31025917, complement)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 6 NC_000006.11 (31110216..31125974, complement)

Chromosome 6 - NC_000006.12Genomic Context describing neighboring genes Neighboring gene psoriasis susceptibility 1 candidate 1 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr6:31105363-31106343 Neighboring gene psoriasis susceptibility 1 candidate 2 Neighboring gene RNA polymerase II subunit L pseudogene 1 Neighboring gene OCT4 hESC enhancer GRCh37_chr6:31123471-31124086 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr6:31124820-31125320 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr6:31125321-31125821 Neighboring gene ReSE screen-validated silencer GRCh37_chr6:31127045-31127228 Neighboring gene OCT4-H3K4me1 hESC enhancer GRCh37_chr6:31128969-31129952 Neighboring gene OCT4-H3K4me1 hESC enhancer GRCh37_chr6:31129953-31130936 Neighboring gene transcription factor 19 Neighboring gene OCT4-H3K4me1 hESC enhancer GRCh37_chr6:31132319-31132900 Neighboring gene OCT4-H3K27ac hESC enhancer GRCh37_chr6:31135533-31136390 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr6:31136391-31137248 Neighboring gene POU class 5 homeobox 1 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr6:31137249-31138106 Neighboring gene POU5F1 5' regulatory region

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: HPA RNA-seq normal tissues HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

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Related articles in PubMed

  1. Segregation of nascent GPCRs in the ER-to-Golgi transport by CCHCR1 via direct interaction. Xu X, et al. J Cell Sci, 2024 Feb 1. PMID 38230433,
  2. Psoriasis-associated genetic polymorphism in North Indian population in the CCHCR1 gene and in a genomic segment flanking the HLA-C region. Gandhi G, et al. Dis Markers, 2011. PMID 22182809, Free PMC Article
  3. Centrosomal localization of the psoriasis candidate gene product, CCHCR1, supports a role in cytoskeletal organization. Tervaniemi MH, et al. PLoS One, 2012. PMID 23189171, Free PMC Article
  4. The CCHCR1 (HCR) gene is relevant for skin steroidogenesis and downregulated in cultured psoriatic keratinocytes. Tiala I, et al. J Mol Med (Berl), 2007 Jun. PMID 17221218
  5. Mapping and identifying genes for asthma and psoriasis. Kere J. Philos Trans R Soc Lond B Biol Sci, 2005 Aug 29. PMID 16096103, Free PMC Article

See all (75) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Segregation of nascent GPCRs in the ER-to-Golgi transport by CCHCR1 via direct interaction.
    Title: Segregation of nascent GPCRs in the ER-to-Golgi transport by CCHCR1 via direct interaction.
  2. Identification of protein/mRNA network involving the PSORS1 locus gene CCHCR1 and the PSORS4 locus gene HAX1.
    Title: Identification of protein/mRNA network involving the PSORS1 locus gene CCHCR1 and the PSORS4 locus gene HAX1.
  3. Alopecia areata susceptibility variant in MHC region impacts expressions of genes contributing to hair keratinization and is involved in hair loss.
    Title: Alopecia areata susceptibility variant in MHC region impacts expressions of genes contributing to hair keratinization and is involved in hair loss.
  4. A Genome-Wide Association Study Identifies Two Novel Susceptible Regions for Squamous Cell Carcinoma of the Head and Neck.
    Title: A Genome-Wide Association Study Identifies Two Novel Susceptible Regions for Squamous Cell Carcinoma of the Head and Neck.
  5. psoriasis candidate gene CCHCR1 expressed at P-bodies and centrosomes
    Title: Intracellular signalling pathways and cytoskeletal functions converge on the psoriasis candidate gene CCHCR1 expressed at P-bodies and centrosomes.
  6. CCHCR1 interacts specifically with the E2 protein of human papillomavirus type 16 on a surface overlapping BRD4 binding
    Title: CCHCR1 interacts specifically with the E2 protein of human papillomavirus type 16 on a surface overlapping BRD4 binding.
  7. Confocal imaging confirmed the localization of CCHCR1 in P-bodies.
    Title: CCHCR1 interacts with EDC4, suggesting its localization in P-bodies.
  8. The centrosomal localization of CCHCR1 provides a connection to the abnormal cell proliferation and offers a link to possible cellular pathways altered in psoriasis.
    Title: Centrosomal localization of the psoriasis candidate gene product, CCHCR1, supports a role in cytoskeletal organization.
  9. Psoriasis is associated with genetic polymorphism in the CCHCR1 gene and in a genomic segment flanking the HLA-C region in the North Indian population.
    Title: Psoriasis-associated genetic polymorphism in North Indian population in the CCHCR1 gene and in a genomic segment flanking the HLA-C region.
  10. Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)
    Title: Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.
Submit: New GeneRIF Correction See all GeneRIFs (17)

Phenotypes

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Find tests for this gene in the NIH Genetic Testing Registry (GTR)

Review eQTL and phenotype association data in this region using PheGenI

EBI GWAS Catalog

Description
A genome-wide association study identifies three new susceptibility loci for ulcerative colitis in the Japanese population.
EBI GWAS Catalog
A whole-genome association study of major determinants for allopurinol-related Stevens-Johnson syndrome and toxic epidermal necrolysis in Japanese patients.
EBI GWAS Catalog
Common variation at 3q26.2, 6p21.33, 17p11.2 and 22q13.1 influences multiple myeloma risk.
EBI GWAS Catalog
Genome-wide association analysis of blood biomarkers in chronic obstructive pulmonary disease.
EBI GWAS Catalog
Genome-wide association study identifies variations in 6p21.3 associated with nevirapine-induced rash.
EBI GWAS Catalog
GWAS of blood cell traits identifies novel associated loci and epistatic interactions in Caucasian and African-American children.
EBI GWAS Catalog
Multiple loci are associated with white blood cell phenotypes.
EBI GWAS Catalog
Seven prostate cancer susceptibility loci identified by a multi-stage genome-wide association study.
EBI GWAS Catalog

Variation

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See Variation Viewer (GRCh37.p13)

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Clone Names

  • MGC126371, MGC126372

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables identical protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell differentiation IEA
Inferred from Electronic Annotation
more info
  
involved_in protein export from nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in centriole IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in centriole IDA
Inferred from Direct Assay
more info
 PubMed 
located_in cytosol IDA
Inferred from Direct Assay
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
coiled-coil alpha-helical rod protein 1
Names
HCR (a-helix coiled-coil rod homologue)
StAR-binding protein
alpha-helical coiled-coil rod protein
putative gene 8 protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_054878.1 RefSeqGene

    Range
    5437..20800
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001105563.3 → NP_001099033.1  coiled-coil alpha-helical rod protein 1 isoform 2

    Status: REVIEWED

    Source sequence(s)
    AL662844
    Consensus CDS
    CCDS47397.1
    UniProtKB/TrEMBL
    A0A1U9X7G4, A0A1U9X7G6, A0A1U9X7G7, A0A1U9X7H0
    Related
    ENSP00000401039.2, ENST00000451521.6
    Conserved Domains (1) summary
    cl25732
    Location:85 → 826
    SMC_N; RecF/RecN/SMC N terminal domain

  2. NM_001105564.2 → NP_001099034.1  coiled-coil alpha-helical rod protein 1 isoform 1

    Status: REVIEWED

    Source sequence(s)
    AL662844
    Consensus CDS
    CCDS43445.1
    UniProtKB/TrEMBL
    A0A0G2JP87
    Related
    ENSP00000379566.3, ENST00000396268.8
    Conserved Domains (2) summary
    pfam07111
    Location:116 → 862
    HCR; Alpha helical coiled-coil rod protein (HCR)
    cl19219
    Location:309 → 390
    DUF342; Protein of unknown function (DUF342)

  3. NM_001394641.1 → NP_001381570.1  coiled-coil alpha-helical rod protein 1 isoform 4

    Status: REVIEWED

    Source sequence(s)
    AL662844
    UniProtKB/TrEMBL
    A0A0G2JP87
    Conserved Domains (1) summary
    pfam07111
    Location:125 → 871
    HCR; Alpha helical coiled-coil rod protein (HCR)

  4. NM_001394642.1 → NP_001381571.1  coiled-coil alpha-helical rod protein 1 isoform 3

    Status: REVIEWED

    Source sequence(s)
    AL662844
    Consensus CDS
    CCDS4695.1
    UniProtKB/Swiss-Prot
    A2ABH6, E9PE84, Q2TB67, Q5SQ82, Q5STE9, Q8TD31, Q9NRK8, Q9NWY9, Q9NXJ4, Q9NXK3, Q9Y6W1, Q9Y6W2
    UniProtKB/TrEMBL
    Q6IAC8
    Conserved Domains (1) summary
    pfam07111
    Location:27 → 773
    HCR; Alpha helical coiled-coil rod protein (HCR)

  5. NM_001394643.1 → NP_001381572.1  coiled-coil alpha-helical rod protein 1 isoform 3

    Status: REVIEWED

    Source sequence(s)
    AL662844
    Consensus CDS
    CCDS4695.1
    UniProtKB/Swiss-Prot
    A2ABH6, E9PE84, Q2TB67, Q5SQ82, Q5STE9, Q8TD31, Q9NRK8, Q9NWY9, Q9NXJ4, Q9NXK3, Q9Y6W1, Q9Y6W2
    UniProtKB/TrEMBL
    Q6IAC8
    Conserved Domains (1) summary
    pfam07111
    Location:27 → 773
    HCR; Alpha helical coiled-coil rod protein (HCR)

  6. NM_001394644.1 → NP_001381573.1  coiled-coil alpha-helical rod protein 1 isoform 3

    Status: REVIEWED

    Source sequence(s)
    AL662844
    Consensus CDS
    CCDS4695.1
    UniProtKB/Swiss-Prot
    A2ABH6, E9PE84, Q2TB67, Q5SQ82, Q5STE9, Q8TD31, Q9NRK8, Q9NWY9, Q9NXJ4, Q9NXK3, Q9Y6W1, Q9Y6W2
    UniProtKB/TrEMBL
    Q6IAC8
    Related
    ENSP00000379561.2, ENST00000396263.6
    Conserved Domains (1) summary
    pfam07111
    Location:27 → 773
    HCR; Alpha helical coiled-coil rod protein (HCR)

  7. NM_001394646.1 → NP_001381575.1  coiled-coil alpha-helical rod protein 1 isoform 5

    Status: REVIEWED

    Source sequence(s)
    AL662844
    UniProtKB/TrEMBL
    Q6IAC8
    Conserved Domains (1) summary
    pfam07111
    Location:27 → 770
    HCR; Alpha helical coiled-coil rod protein (HCR)

  8. NM_001394647.1 → NP_001381576.1  coiled-coil alpha-helical rod protein 1 isoform 6

    Status: REVIEWED

    Source sequence(s)
    AL662844
    UniProtKB/TrEMBL
    Q0EFB6, Q2L6G6
    Conserved Domains (1) summary
    pfam07111
    Location:1 → 747
    HCR; Alpha helical coiled-coil rod protein (HCR)

  9. NM_001394648.1 → NP_001381577.1  coiled-coil alpha-helical rod protein 1 isoform 7

    Status: REVIEWED

    Source sequence(s)
    AL662844
    UniProtKB/TrEMBL
    Q2TB68
    Conserved Domains (1) summary
    pfam07111
    Location:1 → 737
    HCR; Alpha helical coiled-coil rod protein (HCR)

  10. NM_001394649.1 → NP_001381578.1  coiled-coil alpha-helical rod protein 1 isoform 8

    Status: REVIEWED

    Source sequence(s)
    AL662844
    UniProtKB/TrEMBL
    Q0EFB6
    Conserved Domains (1) summary
    pfam07111
    Location:1 → 654
    HCR; Alpha helical coiled-coil rod protein (HCR)

  11. NM_019052.4 → NP_061925.2  coiled-coil alpha-helical rod protein 1 isoform 3

    See identical proteins and their annotated locations for NP_061925.2

    Status: REVIEWED

    Source sequence(s)
    AA356205, AB112474, AB112475, AK000533, BC110534, DC357362
    Consensus CDS
    CCDS4695.1
    UniProtKB/Swiss-Prot
    A2ABH6, E9PE84, Q2TB67, Q5SQ82, Q5STE9, Q8TD31, Q9NRK8, Q9NWY9, Q9NXJ4, Q9NXK3, Q9Y6W1, Q9Y6W2
    UniProtKB/TrEMBL
    Q6IAC8
    Related
    ENSP00000365442.5, ENST00000376266.9
    Conserved Domains (1) summary
    pfam07111
    Location:27 → 773
    HCR; Alpha helical coiled-coil rod protein (HCR)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000006.12 Reference GRCh38.p14 Primary Assembly

    Range
    31142439..31158197 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017010969.2 → XP_016866458.1  coiled-coil alpha-helical rod protein 1 isoform X2

    UniProtKB/TrEMBL
    Q2TB68
    Conserved Domains (1) summary
    pfam07111
    Location:1 → 737
    HCR; Alpha helical coiled-coil rod protein (HCR)

  2. XM_017010968.2 → XP_016866457.1  coiled-coil alpha-helical rod protein 1 isoform X1

    UniProtKB/Swiss-Prot
    A2ABH6, E9PE84, Q2TB67, Q5SQ82, Q5STE9, Q8TD31, Q9NRK8, Q9NWY9, Q9NXJ4, Q9NXK3, Q9Y6W1, Q9Y6W2
    UniProtKB/TrEMBL
    Q6IAC8
    Conserved Domains (1) summary
    pfam07111
    Location:27 → 773
    HCR; Alpha helical coiled-coil rod protein (HCR)

  3. XM_047418911.1 → XP_047274867.1  coiled-coil alpha-helical rod protein 1 isoform X2

  4. XM_011514705.2 → XP_011513007.1  coiled-coil alpha-helical rod protein 1 isoform X2

    See identical proteins and their annotated locations for XP_011513007.1

    UniProtKB/TrEMBL
    Q2TB68
    Conserved Domains (1) summary
    pfam07111
    Location:1 → 737
    HCR; Alpha helical coiled-coil rod protein (HCR)

  5. XM_017010966.2 → XP_016866455.1  coiled-coil alpha-helical rod protein 1 isoform X1

    UniProtKB/Swiss-Prot
    A2ABH6, E9PE84, Q2TB67, Q5SQ82, Q5STE9, Q8TD31, Q9NRK8, Q9NWY9, Q9NXJ4, Q9NXK3, Q9Y6W1, Q9Y6W2
    UniProtKB/TrEMBL
    Q6IAC8
    Conserved Domains (1) summary
    pfam07111
    Location:27 → 773
    HCR; Alpha helical coiled-coil rod protein (HCR)

  6. XM_047418908.1 → XP_047274864.1  coiled-coil alpha-helical rod protein 1 isoform X1

    UniProtKB/Swiss-Prot
    A2ABH6, E9PE84, Q2TB67, Q5SQ82, Q5STE9, Q8TD31, Q9NRK8, Q9NWY9, Q9NXJ4, Q9NXK3, Q9Y6W1, Q9Y6W2

  7. XM_017010964.2 → XP_016866453.1  coiled-coil alpha-helical rod protein 1 isoform X1

    UniProtKB/Swiss-Prot
    A2ABH6, E9PE84, Q2TB67, Q5SQ82, Q5STE9, Q8TD31, Q9NRK8, Q9NWY9, Q9NXJ4, Q9NXK3, Q9Y6W1, Q9Y6W2
    UniProtKB/TrEMBL
    Q6IAC8
    Conserved Domains (1) summary
    pfam07111
    Location:27 → 773
    HCR; Alpha helical coiled-coil rod protein (HCR)

  8. XM_047418910.1 → XP_047274866.1  coiled-coil alpha-helical rod protein 1 isoform X1

    UniProtKB/Swiss-Prot
    A2ABH6, E9PE84, Q2TB67, Q5SQ82, Q5STE9, Q8TD31, Q9NRK8, Q9NWY9, Q9NXJ4, Q9NXK3, Q9Y6W1, Q9Y6W2

  9. XM_047418909.1 → XP_047274865.1  coiled-coil alpha-helical rod protein 1 isoform X1

    UniProtKB/Swiss-Prot
    A2ABH6, E9PE84, Q2TB67, Q5SQ82, Q5STE9, Q8TD31, Q9NRK8, Q9NWY9, Q9NXJ4, Q9NXK3, Q9Y6W1, Q9Y6W2

  10. XM_017010963.2 → XP_016866452.1  coiled-coil alpha-helical rod protein 1 isoform X1

    UniProtKB/Swiss-Prot
    A2ABH6, E9PE84, Q2TB67, Q5SQ82, Q5STE9, Q8TD31, Q9NRK8, Q9NWY9, Q9NXJ4, Q9NXK3, Q9Y6W1, Q9Y6W2
    UniProtKB/TrEMBL
    Q6IAC8
    Conserved Domains (1) summary
    pfam07111
    Location:27 → 773
    HCR; Alpha helical coiled-coil rod protein (HCR)

  11. XM_011514702.3 → XP_011513004.1  coiled-coil alpha-helical rod protein 1 isoform X5

    See identical proteins and their annotated locations for XP_011513004.1

    UniProtKB/TrEMBL
    A0A1U9X7G4, A0A1U9X7G7, A0A1U9X7H0
    Conserved Domains (2) summary
    pfam07111
    Location:94 → 835
    HCR; Alpha helical coiled-coil rod protein (HCR)
    cl19219
    Location:282 → 363
    DUF342; Protein of unknown function (DUF342)

  12. XM_047418914.1 → XP_047274870.1  coiled-coil alpha-helical rod protein 1 isoform X4

  13. XM_047418913.1 → XP_047274869.1  coiled-coil alpha-helical rod protein 1 isoform X3

    Related
    ENST00000509552.5

  14. XM_047418912.1 → XP_047274868.1  coiled-coil alpha-helical rod protein 1 isoform X6

Reference GRCh38.p14 ALT_REF_LOCI_2

Genomic

  1. NT_113891.3 Reference GRCh38.p14 ALT_REF_LOCI_2

    Range
    2624870..2640625 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054329828.1 → XP_054185803.1  coiled-coil alpha-helical rod protein 1 isoform X1

    UniProtKB/TrEMBL
    M1T2K8

  2. XM_054329826.1 → XP_054185801.1  coiled-coil alpha-helical rod protein 1 isoform X1

    UniProtKB/TrEMBL
    M1T2K8

  3. XM_054329829.1 → XP_054185804.1  coiled-coil alpha-helical rod protein 1 isoform X1

    UniProtKB/TrEMBL
    M1T2K8

  4. XM_054329827.1 → XP_054185802.1  coiled-coil alpha-helical rod protein 1 isoform X1

    UniProtKB/TrEMBL
    M1T2K8

  5. XM_054329830.1 → XP_054185805.1  coiled-coil alpha-helical rod protein 1 isoform X2

    UniProtKB/TrEMBL
    M1TIV4

  6. XM_054329832.1 → XP_054185807.1  coiled-coil alpha-helical rod protein 1 isoform X4

  7. XM_054329831.1 → XP_054185806.1  coiled-coil alpha-helical rod protein 1 isoform X3

Reference GRCh38.p14 ALT_REF_LOCI_3

Genomic

  1. NT_167245.2 Reference GRCh38.p14 ALT_REF_LOCI_3

    Range
    2401761..2417517 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054330312.1 → XP_054186287.1  coiled-coil alpha-helical rod protein 1 isoform X1

    UniProtKB/TrEMBL
    M1T2K8

  2. XM_054330310.1 → XP_054186285.1  coiled-coil alpha-helical rod protein 1 isoform X1

    UniProtKB/TrEMBL
    M1T2K8

  3. XM_054330313.1 → XP_054186288.1  coiled-coil alpha-helical rod protein 1 isoform X1

    UniProtKB/TrEMBL
    M1T2K8

  4. XM_054330311.1 → XP_054186286.1  coiled-coil alpha-helical rod protein 1 isoform X1

    UniProtKB/TrEMBL
    M1T2K8

  5. XM_054330314.1 → XP_054186289.1  coiled-coil alpha-helical rod protein 1 isoform X2

    UniProtKB/TrEMBL
    M1TIV4

  6. XM_054330316.1 → XP_054186291.1  coiled-coil alpha-helical rod protein 1 isoform X4

  7. XM_054330315.1 → XP_054186290.1  coiled-coil alpha-helical rod protein 1 isoform X3

Reference GRCh38.p14 ALT_REF_LOCI_4

Genomic

  1. NT_167246.2 Reference GRCh38.p14 ALT_REF_LOCI_4

    Range
    2452954..2468732 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054330610.1 → XP_054186585.1  coiled-coil alpha-helical rod protein 1 isoform X2

    UniProtKB/TrEMBL
    D2IYK9

  2. XM_054330609.1 → XP_054186584.1  coiled-coil alpha-helical rod protein 1 isoform X2

    UniProtKB/TrEMBL
    D2IYK9

  3. XM_054330607.1 → XP_054186582.1  coiled-coil alpha-helical rod protein 1 isoform X1

    UniProtKB/TrEMBL
    B0S7V6

  4. XM_054330608.1 → XP_054186583.1  coiled-coil alpha-helical rod protein 1 isoform X1

    UniProtKB/TrEMBL
    B0S7V6

  5. XM_054330611.1 → XP_054186586.1  coiled-coil alpha-helical rod protein 1 isoform X2

    UniProtKB/TrEMBL
    D2IYK9

  6. XM_054330613.1 → XP_054186588.1  coiled-coil alpha-helical rod protein 1 isoform X4

  7. XM_054330612.1 → XP_054186587.1  coiled-coil alpha-helical rod protein 1 isoform X3

Reference GRCh38.p14 ALT_REF_LOCI_5

Genomic

  1. NT_167247.2 Reference GRCh38.p14 ALT_REF_LOCI_5

    Range
    2486567..2502346 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054330830.1 → XP_054186805.1  coiled-coil alpha-helical rod protein 1 isoform X2

    UniProtKB/TrEMBL
    D2IYK9

  2. XM_054330829.1 → XP_054186804.1  coiled-coil alpha-helical rod protein 1 isoform X2

    UniProtKB/TrEMBL
    D2IYK9

  3. XM_054330827.1 → XP_054186802.1  coiled-coil alpha-helical rod protein 1 isoform X1

    UniProtKB/TrEMBL
    B0S7V6

  4. XM_054330828.1 → XP_054186803.1  coiled-coil alpha-helical rod protein 1 isoform X1

    UniProtKB/TrEMBL
    B0S7V6

  5. XM_054330831.1 → XP_054186806.1  coiled-coil alpha-helical rod protein 1 isoform X2

    UniProtKB/TrEMBL
    D2IYK9

  6. XM_054330833.1 → XP_054186808.1  coiled-coil alpha-helical rod protein 1 isoform X4

  7. XM_054330832.1 → XP_054186807.1  coiled-coil alpha-helical rod protein 1 isoform X3

Reference GRCh38.p14 ALT_REF_LOCI_6

Genomic

  1. NT_167248.2 Reference GRCh38.p14 ALT_REF_LOCI_6

    Range
    2400454..2416229 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054331089.1 → XP_054187064.1  coiled-coil alpha-helical rod protein 1 isoform X8

    UniProtKB/TrEMBL
    B4DIA2

  2. XM_054331091.1 → XP_054187066.1  coiled-coil alpha-helical rod protein 1 isoform X9

  3. XM_054331090.1 → XP_054187065.1  coiled-coil alpha-helical rod protein 1 isoform X2

  4. XM_054331087.1 → XP_054187062.1  coiled-coil alpha-helical rod protein 1 isoform X1

    UniProtKB/Swiss-Prot
    A2ABH6, E9PE84, Q2TB67, Q5SQ82, Q5STE9, Q8TD31, Q9NRK8, Q9NWY9, Q9NXJ4, Q9NXK3, Q9Y6W1, Q9Y6W2

  5. XM_054331088.1 → XP_054187063.1  coiled-coil alpha-helical rod protein 1 isoform X1

    UniProtKB/Swiss-Prot
    A2ABH6, E9PE84, Q2TB67, Q5SQ82, Q5STE9, Q8TD31, Q9NRK8, Q9NWY9, Q9NXJ4, Q9NXK3, Q9Y6W1, Q9Y6W2

  6. XM_054331086.1 → XP_054187061.1  coiled-coil alpha-helical rod protein 1 isoform X5

  7. XM_054331085.1 → XP_054187060.1  coiled-coil alpha-helical rod protein 1 isoform X7

  8. XM_054331093.1 → XP_054187068.1  coiled-coil alpha-helical rod protein 1 isoform X4

  9. XM_054331092.1 → XP_054187067.1  coiled-coil alpha-helical rod protein 1 isoform X6

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060930.1 Alternate T2T-CHM13v2.0

    Range
    31010125..31025917 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054355686.1 → XP_054211661.1  coiled-coil alpha-helical rod protein 1 isoform X1

    UniProtKB/TrEMBL
    M1T2K8

  2. XM_054355696.1 → XP_054211671.1  coiled-coil alpha-helical rod protein 1 isoform X2

    UniProtKB/TrEMBL
    M1TIV4

  3. XM_054355695.1 → XP_054211670.1  coiled-coil alpha-helical rod protein 1 isoform X2

    UniProtKB/TrEMBL
    M1TIV4

  4. XM_054355687.1 → XP_054211662.1  coiled-coil alpha-helical rod protein 1 isoform X1

    UniProtKB/TrEMBL
    M1T2K8

  5. XM_054355697.1 → XP_054211672.1  coiled-coil alpha-helical rod protein 1 isoform X2

    UniProtKB/TrEMBL
    M1TIV4

  6. XM_054355690.1 → XP_054211665.1  coiled-coil alpha-helical rod protein 1 isoform X1

    UniProtKB/TrEMBL
    M1T2K8

  7. XM_054355685.1 → XP_054211660.1  coiled-coil alpha-helical rod protein 1 isoform X1

    UniProtKB/TrEMBL
    M1T2K8

  8. XM_054355688.1 → XP_054211663.1  coiled-coil alpha-helical rod protein 1 isoform X1

    UniProtKB/TrEMBL
    M1T2K8

  9. XM_054355693.1 → XP_054211668.1  coiled-coil alpha-helical rod protein 1 isoform X1

    UniProtKB/TrEMBL
    M1T2K8

  10. XM_054355692.1 → XP_054211667.1  coiled-coil alpha-helical rod protein 1 isoform X1

    UniProtKB/TrEMBL
    M1T2K8

  11. XM_054355689.1 → XP_054211664.1  coiled-coil alpha-helical rod protein 1 isoform X1

    UniProtKB/TrEMBL
    M1T2K8

  12. XM_054355691.1 → XP_054211666.1  coiled-coil alpha-helical rod protein 1 isoform X1

    UniProtKB/TrEMBL
    M1T2K8

  13. XM_054355694.1 → XP_054211669.1  coiled-coil alpha-helical rod protein 1 isoform X2

    UniProtKB/TrEMBL
    M1TIV4

  14. XM_054355700.1 → XP_054211675.1  coiled-coil alpha-helical rod protein 1 isoform X4

  15. XM_054355699.1 → XP_054211674.1  coiled-coil alpha-helical rod protein 1 isoform X3

  16. XM_054355698.1 → XP_054211673.1  coiled-coil alpha-helical rod protein 1 isoform X3

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001394645.1: Suppressed sequence

    Description
    NM_001394645.1: This RefSeq record was removed by NCBI staff. Contact info@ncbi.nlm.nih.gov for further information.
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8TD31.2 GenPept UniProtKB/Swiss-Prot:Q8TD31

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