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BCOR BCL6 corepressor [ Homo sapiens (human) ]

Gene ID: 54880, updated on 13-May-2024

Summary

Official Symbol
BCORprovided by HGNC
Official Full Name
BCL6 corepressorprovided by HGNC
Primary source
HGNC:HGNC:20893
See related
Ensembl:ENSG00000183337 MIM:300485; AllianceGenome:HGNC:20893
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
MAA2; ANOP2; MCOPS2
Summary
The protein encoded by this gene was identified as an interacting corepressor of BCL6, a POZ/zinc finger transcription repressor that is required for germinal center formation and may influence apoptosis. This protein selectively interacts with the POZ domain of BCL6, but not with eight other POZ proteins. Specific class I and II histone deacetylases (HDACs) have been shown to interact with this protein, which suggests a possible link between the two classes of HDACs. Several transcript variants encoding different isoforms have been found for this gene. A pseudogene of this gene is found on chromosome Y.[provided by RefSeq, Jun 2010]
Expression
Ubiquitous expression in thyroid (RPKM 8.0), lymph node (RPKM 7.0) and 25 other tissues See more
Orthologs
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Try the new Transcript table

Genomic context

See BCOR in Genome Data Viewer
Location:
Xp11.4
Exon count:
22
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) X NC_000023.11 (40051246..40177329, complement)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) X NC_060947.1 (39452491..39578567, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) X NC_000023.10 (39910499..40036582, complement)

Chromosome X - NC_000023.11Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105373180 Neighboring gene H3K4me1 hESC enhancer GRCh37_chrX:39788469-39788968 Neighboring gene H3K4me1 hESC enhancer GRCh37_chrX:39787967-39788468 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 29533 Neighboring gene H3K4me1 hESC enhancer GRCh37_chrX:39808059-39808558 Neighboring gene ReSE screen-validated silencer GRCh37_chrX:39813184-39813412 Neighboring gene H3K4me1 hESC enhancer GRCh37_chrX:39828711-39829255 Neighboring gene H3K4me1 hESC enhancer GRCh37_chrX:39832750-39833500 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chrX:39863451-39863973 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chrX:39865487-39866423 Neighboring gene H3K4me1 hESC enhancer GRCh37_chrX:39867643-39868270 Neighboring gene H3K4me1 hESC enhancer GRCh37_chrX:39871294-39872017 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 20740 Neighboring gene H3K27ac hESC enhancer GRCh37_chrX:39873755-39874254 Neighboring gene long intergenic non-protein coding RNA 3053 Neighboring gene H3K4me1 hESC enhancer GRCh37_chrX:39918103-39918602 Neighboring gene MED14-independent group 3 enhancer GRCh37_chrX:39932994-39934193 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 20741 Neighboring gene NANOG-H3K27ac hESC enhancer GRCh37_chrX:39950161-39950788 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chrX:39952045-39952671 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 29534 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 20746 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 20745 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 20744 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 20743 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 20742 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 20747 Neighboring gene H3K4me1 hESC enhancer GRCh37_chrX:39959601-39960121 Neighboring gene translation initiation factor IF-2-like Neighboring gene H3K4me1 hESC enhancer GRCh37_chrX:39961792-39962382 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 20748 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 20749 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 29535 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 20752 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 20750 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 20751 Neighboring gene H3K4me1 hESC enhancer GRCh37_chrX:39966379-39967135 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 20753 Neighboring gene ReSE screen-validated silencer GRCh37_chrX:39971030-39971309 Neighboring gene H3K4me1 hESC enhancer GRCh37_chrX:39999891-40000415 Neighboring gene H3K4me1 hESC enhancer GRCh37_chrX:40007775-40008318 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 20754 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chrX:40015867-40016606 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chrX:40016607-40017346 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 20755 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 20756 Neighboring gene OCT4-NANOG-H3K4me1 hESC enhancer GRCh37_chrX:40028374-40029064 Neighboring gene H3K4me1 hESC enhancer GRCh37_chrX:40029065-40029755 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 20757 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 20758 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 29537 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 20759 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 20760 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 20761 Neighboring gene ReSE screen-validated silencer GRCh37_chrX:40041386-40041565 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 20762 Neighboring gene H3K27ac hESC enhancer GRCh37_chrX:40070301-40070852 Neighboring gene OCT4-NANOG-H3K4me1 hESC enhancer GRCh37_chrX:40097124-40097650 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 29538 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 29539 Neighboring gene Sharpr-MPRA regulatory region 4836 Neighboring gene long intergenic non-protein coding RNA 3099 Neighboring gene small nucleolar RNA U13 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 29540 Neighboring gene uncharacterized LOC105373182 Neighboring gene inosine monophosphate dehydrogenase 1 pseudogene 2

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Phenotypes

Associated conditions

Description Tests
Microphthalmia, syndromic 1
MedGen: C0796016 OMIM: 309800 GeneReviews: Not available
Compare labs
Oculofaciocardiodental syndrome
MedGen: C1846265 OMIM: 300166 GeneReviews: Not available
Compare labs

Copy number response

Description
Copy number response
Triplosensitivity

No evidence available (Last evaluated 2012-10-04)

ClinGen Genome Curation Page
Haploinsufficency

Sufficient evidence for dosage pathogenicity (Last evaluated 2012-10-04)

ClinGen Genome Curation PagePubMed

EBI GWAS Catalog

Description
Genome-wide association studies of pit-and-fissure- and smooth-surface caries in permanent dentition.
EBI GWAS Catalog

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Clone Names

  • FLJ20285, FLJ38041, KIAA1575, MGC71031, MGC131961

Gene Ontology Provided by GOA

Component Evidence Code Pubs
part_of BCOR complex IDA
Inferred from Direct Assay
more info
PubMed 
located_in nucleoplasm IDA
Inferred from Direct Assay
more info
 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in nucleus IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
BCL-6 corepressor
Names
BCL-6 coreceptor
BCL-6 interacting corepressor
BCL6 interacting corepressor

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_008880.1 RefSeqGene

    Range
    5001..131084
    Download
    GenBank, FASTA, Sequence Viewer (Graphics), LRG_627

mRNA and Protein(s)

  1. NM_001123383.1NP_001116855.1  BCL-6 corepressor isoform a

    See identical proteins and their annotated locations for NP_001116855.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (3) differs in the 5' UTR and uses an alternate in-frame splice site compared to variant 5. The resulting isoform (a) has the same N- and C-termini but is shorter compared to isoform c. Variants 1 and 3 both encode the same isoform (a).
    Source sequence(s)
    AC092198, AK056538, BC114220
    Consensus CDS
    CCDS14250.1
    UniProtKB/TrEMBL
    H7C2V9
    Related
    ENSP00000345923.4, ENST00000342274.8
    Conserved Domains (5) summary
    cd00204
    Location:14231531
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    cd14261
    Location:15981712
    PUFD; PCGF Ub-like fold discriminator of BCOR
    pfam12796
    Location:14331524
    Ank_2; Ankyrin repeats (3 copies)
    pfam15808
    Location:11681380
    BCOR; BCL-6 co-repressor, non-ankyrin-repeat region
    sd00045
    Location:14291460
    ANK; ANK repeat [structural motif]
  2. NM_001123384.2NP_001116856.1  BCL-6 corepressor isoform b

    See identical proteins and their annotated locations for NP_001116856.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (4) differs in the 5' UTR and lacks two alternate in-frame segments compared to variant 5. The resulting isoform (b) has the same N- and C-termini but is shorter compared to isoform c.
    Source sequence(s)
    AC092198, BC114220
    Consensus CDS
    CCDS48092.1
    UniProtKB/TrEMBL
    H7C2V9
    Related
    ENSP00000367716.4, ENST00000378455.8
    Conserved Domains (5) summary
    cd00204
    Location:14051513
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    cd14261
    Location:15801694
    PUFD; PCGF Ub-like fold discriminator of BCOR
    pfam12796
    Location:14151506
    Ank_2; Ankyrin repeats (3 copies)
    pfam15808
    Location:11501362
    BCOR; BCL-6 co-repressor, non-ankyrin-repeat region
    sd00045
    Location:14111442
    ANK; ANK repeat [structural motif]
  3. NM_001123385.2NP_001116857.1  BCL-6 corepressor isoform c

    See identical proteins and their annotated locations for NP_001116857.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (5) represents the longest transcript and encodes the longest isoform (c).
    Source sequence(s)
    AC092198, AK056538, AL591802, AL698729, AY316592, BC114220
    Consensus CDS
    CCDS48093.1
    UniProtKB/Swiss-Prot
    D3DWB3, D3DWB4, Q29RF6, Q6P4B6, Q6W2J9, Q7Z2K7, Q8TEB4, Q96DB3, Q9H232, Q9H233, Q9HCJ7, Q9NXF2
    UniProtKB/TrEMBL
    H7C2V9
    Related
    ENSP00000367705.4, ENST00000378444.9
    Conserved Domains (5) summary
    cd00204
    Location:14571565
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    cd14261
    Location:16321746
    PUFD; PCGF Ub-like fold discriminator of BCOR
    pfam12796
    Location:14671558
    Ank_2; Ankyrin repeats (3 copies)
    pfam15808
    Location:12021414
    BCOR; BCL-6 co-repressor, non-ankyrin-repeat region
    sd00045
    Location:14631494
    ANK; ANK repeat [structural motif]
  4. NM_017745.6NP_060215.4  BCL-6 corepressor isoform a

    See identical proteins and their annotated locations for NP_060215.4

    Status: REVIEWED

    Description
    Transcript Variant: This variant (1) uses an alternate in-frame splice site compared to variant 5. The resulting isoform (a) has the same N- and C-termini but is shorter compared to isoform c. Variants 1 and 3 both encode the same isoform (a).
    Source sequence(s)
    AC092198, AK056538, AL591802, AL698729, BC114220
    Consensus CDS
    CCDS14250.1
    UniProtKB/TrEMBL
    H7C2V9
    Related
    ENSP00000380512.3, ENST00000397354.7
    Conserved Domains (5) summary
    cd00204
    Location:14231531
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    cd14261
    Location:15981712
    PUFD; PCGF Ub-like fold discriminator of BCOR
    pfam12796
    Location:14331524
    Ank_2; Ankyrin repeats (3 copies)
    pfam15808
    Location:11681380
    BCOR; BCL-6 co-repressor, non-ankyrin-repeat region
    sd00045
    Location:14291460
    ANK; ANK repeat [structural motif]

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000023.11 Reference GRCh38.p14 Primary Assembly

    Range
    40051246..40177329 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_047442202.1XP_047298158.1  BCL-6 corepressor isoform X2

    UniProtKB/TrEMBL
    H7C231
  2. XM_005272616.2XP_005272673.1  BCL-6 corepressor isoform X1

    See identical proteins and their annotated locations for XP_005272673.1

    UniProtKB/Swiss-Prot
    D3DWB3, D3DWB4, Q29RF6, Q6P4B6, Q6W2J9, Q7Z2K7, Q8TEB4, Q96DB3, Q9H232, Q9H233, Q9HCJ7, Q9NXF2
    UniProtKB/TrEMBL
    H7C2V9
    Related
    ENSP00000499892.2, ENST00000672922.2
    Conserved Domains (5) summary
    cd00204
    Location:14571565
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    cd14261
    Location:16321746
    PUFD; PCGF Ub-like fold discriminator of BCOR
    pfam12796
    Location:14671558
    Ank_2; Ankyrin repeats (3 copies)
    pfam15808
    Location:12021414
    BCOR; BCL-6 co-repressor, non-ankyrin-repeat region
    sd00045
    Location:14631494
    ANK; ANK repeat [structural motif]
  3. XM_047442223.1XP_047298179.1  BCL-6 corepressor isoform X4

  4. XM_047442205.1XP_047298161.1  BCL-6 corepressor isoform X2

    UniProtKB/TrEMBL
    H7C231
  5. XM_047442213.1XP_047298169.1  BCL-6 corepressor isoform X3

  6. XM_011543931.3XP_011542233.1  BCL-6 corepressor isoform X1

    See identical proteins and their annotated locations for XP_011542233.1

    UniProtKB/Swiss-Prot
    D3DWB3, D3DWB4, Q29RF6, Q6P4B6, Q6W2J9, Q7Z2K7, Q8TEB4, Q96DB3, Q9H232, Q9H233, Q9HCJ7, Q9NXF2
    UniProtKB/TrEMBL
    H7C2V9
    Conserved Domains (5) summary
    cd00204
    Location:14571565
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    cd14261
    Location:16321746
    PUFD; PCGF Ub-like fold discriminator of BCOR
    pfam12796
    Location:14671558
    Ank_2; Ankyrin repeats (3 copies)
    pfam15808
    Location:12021414
    BCOR; BCL-6 co-repressor, non-ankyrin-repeat region
    sd00045
    Location:14631494
    ANK; ANK repeat [structural motif]
  7. XM_047442219.1XP_047298175.1  BCL-6 corepressor isoform X4

  8. XM_047442201.1XP_047298157.1  BCL-6 corepressor isoform X2

    UniProtKB/TrEMBL
    H7C231
  9. XM_047442210.1XP_047298166.1  BCL-6 corepressor isoform X3

  10. XM_011543930.2XP_011542232.1  BCL-6 corepressor isoform X1

    See identical proteins and their annotated locations for XP_011542232.1

    UniProtKB/Swiss-Prot
    D3DWB3, D3DWB4, Q29RF6, Q6P4B6, Q6W2J9, Q7Z2K7, Q8TEB4, Q96DB3, Q9H232, Q9H233, Q9HCJ7, Q9NXF2
    UniProtKB/TrEMBL
    H7C2V9
    Conserved Domains (5) summary
    cd00204
    Location:14571565
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    cd14261
    Location:16321746
    PUFD; PCGF Ub-like fold discriminator of BCOR
    pfam12796
    Location:14671558
    Ank_2; Ankyrin repeats (3 copies)
    pfam15808
    Location:12021414
    BCOR; BCL-6 co-repressor, non-ankyrin-repeat region
    sd00045
    Location:14631494
    ANK; ANK repeat [structural motif]
  11. XM_047442221.1XP_047298177.1  BCL-6 corepressor isoform X4

  12. XM_047442208.1XP_047298164.1  BCL-6 corepressor isoform X2

    UniProtKB/TrEMBL
    H7C231
  13. XM_047442211.1XP_047298167.1  BCL-6 corepressor isoform X3

  14. XM_011543929.3XP_011542231.1  BCL-6 corepressor isoform X1

    See identical proteins and their annotated locations for XP_011542231.1

    UniProtKB/Swiss-Prot
    D3DWB3, D3DWB4, Q29RF6, Q6P4B6, Q6W2J9, Q7Z2K7, Q8TEB4, Q96DB3, Q9H232, Q9H233, Q9HCJ7, Q9NXF2
    UniProtKB/TrEMBL
    H7C2V9
    Conserved Domains (5) summary
    cd00204
    Location:14571565
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    cd14261
    Location:16321746
    PUFD; PCGF Ub-like fold discriminator of BCOR
    pfam12796
    Location:14671558
    Ank_2; Ankyrin repeats (3 copies)
    pfam15808
    Location:12021414
    BCOR; BCL-6 co-repressor, non-ankyrin-repeat region
    sd00045
    Location:14631494
    ANK; ANK repeat [structural motif]
  15. XM_047442228.1XP_047298184.1  BCL-6 corepressor isoform X4

  16. XM_047442197.1XP_047298153.1  BCL-6 corepressor isoform X1

    UniProtKB/Swiss-Prot
    D3DWB3, D3DWB4, Q29RF6, Q6P4B6, Q6W2J9, Q7Z2K7, Q8TEB4, Q96DB3, Q9H232, Q9H233, Q9HCJ7, Q9NXF2
    Related
    ENSP00000483217.2, ENST00000615339.2
  17. XM_047442214.1XP_047298170.1  BCL-6 corepressor isoform X3

  18. XM_047442216.1XP_047298172.1  BCL-6 corepressor isoform X3

  19. XM_047442207.1XP_047298163.1  BCL-6 corepressor isoform X2

    UniProtKB/TrEMBL
    H7C231
  20. XM_047442224.1XP_047298180.1  BCL-6 corepressor isoform X4

  21. XM_047442204.1XP_047298160.1  BCL-6 corepressor isoform X2

    UniProtKB/TrEMBL
    H7C231
  22. XM_047442198.1XP_047298154.1  BCL-6 corepressor isoform X1

    UniProtKB/Swiss-Prot
    D3DWB3, D3DWB4, Q29RF6, Q6P4B6, Q6W2J9, Q7Z2K7, Q8TEB4, Q96DB3, Q9H232, Q9H233, Q9HCJ7, Q9NXF2
  23. XM_047442199.1XP_047298155.1  BCL-6 corepressor isoform X1

    UniProtKB/Swiss-Prot
    D3DWB3, D3DWB4, Q29RF6, Q6P4B6, Q6W2J9, Q7Z2K7, Q8TEB4, Q96DB3, Q9H232, Q9H233, Q9HCJ7, Q9NXF2
  24. XM_047442218.1XP_047298174.1  BCL-6 corepressor isoform X3

  25. XM_047442227.1XP_047298183.1  BCL-6 corepressor isoform X4

  26. XM_047442196.1XP_047298152.1  BCL-6 corepressor isoform X1

    UniProtKB/Swiss-Prot
    D3DWB3, D3DWB4, Q29RF6, Q6P4B6, Q6W2J9, Q7Z2K7, Q8TEB4, Q96DB3, Q9H232, Q9H233, Q9HCJ7, Q9NXF2
    Related
    ENSP00000505507.1, ENST00000680831.1
  27. XM_047442222.1XP_047298178.1  BCL-6 corepressor isoform X4

  28. XM_047442209.1XP_047298165.1  BCL-6 corepressor isoform X2

    UniProtKB/TrEMBL
    H7C231
  29. XM_047442217.1XP_047298173.1  BCL-6 corepressor isoform X3

  30. XM_047442220.1XP_047298176.1  BCL-6 corepressor isoform X4

  31. XM_047442203.1XP_047298159.1  BCL-6 corepressor isoform X2

    UniProtKB/TrEMBL
    H7C231
    Related
    ENSP00000403823.3, ENST00000427012.3
  32. XM_047442212.1XP_047298168.1  BCL-6 corepressor isoform X3

    Related
    ENSP00000408006.2, ENST00000413905.6
  33. XM_005272618.4XP_005272675.1  BCL-6 corepressor isoform X1

    See identical proteins and their annotated locations for XP_005272675.1

    UniProtKB/Swiss-Prot
    D3DWB3, D3DWB4, Q29RF6, Q6P4B6, Q6W2J9, Q7Z2K7, Q8TEB4, Q96DB3, Q9H232, Q9H233, Q9HCJ7, Q9NXF2
    UniProtKB/TrEMBL
    H7C2V9
    Related
    ENSP00000384485.3, ENST00000406200.4
    Conserved Domains (5) summary
    cd00204
    Location:14571565
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    cd14261
    Location:16321746
    PUFD; PCGF Ub-like fold discriminator of BCOR
    pfam12796
    Location:14671558
    Ank_2; Ankyrin repeats (3 copies)
    pfam15808
    Location:12021414
    BCOR; BCL-6 co-repressor, non-ankyrin-repeat region
    sd00045
    Location:14631494
    ANK; ANK repeat [structural motif]
  34. XM_005272620.5XP_005272677.1  BCL-6 corepressor isoform X4

    See identical proteins and their annotated locations for XP_005272677.1

    UniProtKB/TrEMBL
    H7C2V9
    Conserved Domains (5) summary
    cd00204
    Location:14051513
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    cd14261
    Location:15801694
    PUFD; PCGF Ub-like fold discriminator of BCOR
    pfam12796
    Location:14151506
    Ank_2; Ankyrin repeats (3 copies)
    pfam15808
    Location:11501362
    BCOR; BCL-6 co-repressor, non-ankyrin-repeat region
    sd00045
    Location:14111442
    ANK; ANK repeat [structural motif]
  35. XM_005272619.5XP_005272676.1  BCL-6 corepressor isoform X2

    UniProtKB/TrEMBL
    H7C231, H7C2V9
    Conserved Domains (5) summary
    cd00204
    Location:14391547
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    cd14261
    Location:16141728
    PUFD; PCGF Ub-like fold discriminator of BCOR
    pfam12796
    Location:14491540
    Ank_2; Ankyrin repeats (3 copies)
    pfam15808
    Location:11841396
    BCOR; BCL-6 co-repressor, non-ankyrin-repeat region
    sd00045
    Location:14451476
    ANK; ANK repeat [structural motif]
  36. XM_017029616.3XP_016885105.1  BCL-6 corepressor isoform X5

    UniProtKB/TrEMBL
    H7BZ37, H7C2V9
    Related
    ENSP00000387552.2, ENST00000442018.6
  37. XM_017029615.2XP_016885104.1  BCL-6 corepressor isoform X3

    UniProtKB/TrEMBL
    H7C2V9
    Related
    ENSP00000500446.1, ENST00000673391.1
    Conserved Domains (5) summary
    cd00204
    Location:14231531
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    cd14261
    Location:15981712
    PUFD; PCGF Ub-like fold discriminator of BCOR
    pfam12796
    Location:14331524
    Ank_2; Ankyrin repeats (3 copies)
    pfam15808
    Location:11681380
    BCOR; BCL-6 co-repressor, non-ankyrin-repeat region
    sd00045
    Location:14291460
    ANK; ANK repeat [structural motif]
  38. XM_006724536.4XP_006724599.1  BCL-6 corepressor isoform X1

    See identical proteins and their annotated locations for XP_006724599.1

    UniProtKB/Swiss-Prot
    D3DWB3, D3DWB4, Q29RF6, Q6P4B6, Q6W2J9, Q7Z2K7, Q8TEB4, Q96DB3, Q9H232, Q9H233, Q9HCJ7, Q9NXF2
    UniProtKB/TrEMBL
    H7C2V9
    Conserved Domains (5) summary
    cd00204
    Location:14571565
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    cd14261
    Location:16321746
    PUFD; PCGF Ub-like fold discriminator of BCOR
    pfam12796
    Location:14671558
    Ank_2; Ankyrin repeats (3 copies)
    pfam15808
    Location:12021414
    BCOR; BCL-6 co-repressor, non-ankyrin-repeat region
    sd00045
    Location:14631494
    ANK; ANK repeat [structural motif]
  39. XM_047442225.1XP_047298181.1  BCL-6 corepressor isoform X4

  40. XM_047442206.1XP_047298162.1  BCL-6 corepressor isoform X2

    UniProtKB/TrEMBL
    H7C231
  41. XM_047442226.1XP_047298182.1  BCL-6 corepressor isoform X4

  42. XM_047442215.1XP_047298171.1  BCL-6 corepressor isoform X3

  43. XM_047442200.1XP_047298156.1  BCL-6 corepressor isoform X1

    UniProtKB/Swiss-Prot
    D3DWB3, D3DWB4, Q29RF6, Q6P4B6, Q6W2J9, Q7Z2K7, Q8TEB4, Q96DB3, Q9H232, Q9H233, Q9HCJ7, Q9NXF2
    Related
    ENSP00000505761.1, ENST00000679513.1

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060947.1 Alternate T2T-CHM13v2.0

    Range
    39452491..39578567 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054327306.1XP_054183281.1  BCL-6 corepressor isoform X2

    UniProtKB/TrEMBL
    H7C231
  2. XM_054327293.1XP_054183268.1  BCL-6 corepressor isoform X1

    UniProtKB/Swiss-Prot
    D3DWB3, D3DWB4, Q29RF6, Q6P4B6, Q6W2J9, Q7Z2K7, Q8TEB4, Q96DB3, Q9H232, Q9H233, Q9HCJ7, Q9NXF2
  3. XM_054327314.1XP_054183289.1  BCL-6 corepressor isoform X3

  4. XM_054327295.1XP_054183270.1  BCL-6 corepressor isoform X1

    UniProtKB/Swiss-Prot
    D3DWB3, D3DWB4, Q29RF6, Q6P4B6, Q6W2J9, Q7Z2K7, Q8TEB4, Q96DB3, Q9H232, Q9H233, Q9HCJ7, Q9NXF2
  5. XM_054327309.1XP_054183284.1  BCL-6 corepressor isoform X2

    UniProtKB/TrEMBL
    H7C231
  6. XM_054327326.1XP_054183301.1  BCL-6 corepressor isoform X4

  7. XM_054327331.1XP_054183306.1  BCL-6 corepressor isoform X4

  8. XM_054327321.1XP_054183296.1  BCL-6 corepressor isoform X3

  9. XM_054327301.1XP_054183276.1  BCL-6 corepressor isoform X1

    UniProtKB/Swiss-Prot
    D3DWB3, D3DWB4, Q29RF6, Q6P4B6, Q6W2J9, Q7Z2K7, Q8TEB4, Q96DB3, Q9H232, Q9H233, Q9HCJ7, Q9NXF2
  10. XM_054327320.1XP_054183295.1  BCL-6 corepressor isoform X3

  11. XM_054327333.1XP_054183308.1  BCL-6 corepressor isoform X4

  12. XM_054327312.1XP_054183287.1  BCL-6 corepressor isoform X2

    UniProtKB/TrEMBL
    H7C231
  13. XM_054327294.1XP_054183269.1  BCL-6 corepressor isoform X1

    UniProtKB/Swiss-Prot
    D3DWB3, D3DWB4, Q29RF6, Q6P4B6, Q6W2J9, Q7Z2K7, Q8TEB4, Q96DB3, Q9H232, Q9H233, Q9HCJ7, Q9NXF2
  14. XM_054327305.1XP_054183280.1  BCL-6 corepressor isoform X2

    UniProtKB/TrEMBL
    H7C231
  15. XM_054327334.1XP_054183309.1  BCL-6 corepressor isoform X4

  16. XM_054327297.1XP_054183272.1  BCL-6 corepressor isoform X1

    UniProtKB/Swiss-Prot
    D3DWB3, D3DWB4, Q29RF6, Q6P4B6, Q6W2J9, Q7Z2K7, Q8TEB4, Q96DB3, Q9H232, Q9H233, Q9HCJ7, Q9NXF2
  17. XM_054327315.1XP_054183290.1  BCL-6 corepressor isoform X3

  18. XM_054327317.1XP_054183292.1  BCL-6 corepressor isoform X3

  19. XM_054327311.1XP_054183286.1  BCL-6 corepressor isoform X2

    UniProtKB/TrEMBL
    H7C231
  20. XM_054327327.1XP_054183302.1  BCL-6 corepressor isoform X4

  21. XM_054327308.1XP_054183283.1  BCL-6 corepressor isoform X2

    UniProtKB/TrEMBL
    H7C231
  22. XM_054327299.1XP_054183274.1  BCL-6 corepressor isoform X1

    UniProtKB/Swiss-Prot
    D3DWB3, D3DWB4, Q29RF6, Q6P4B6, Q6W2J9, Q7Z2K7, Q8TEB4, Q96DB3, Q9H232, Q9H233, Q9HCJ7, Q9NXF2
  23. XM_054327300.1XP_054183275.1  BCL-6 corepressor isoform X1

    UniProtKB/Swiss-Prot
    D3DWB3, D3DWB4, Q29RF6, Q6P4B6, Q6W2J9, Q7Z2K7, Q8TEB4, Q96DB3, Q9H232, Q9H233, Q9HCJ7, Q9NXF2
  24. XM_054327319.1XP_054183294.1  BCL-6 corepressor isoform X3

  25. XM_054327330.1XP_054183305.1  BCL-6 corepressor isoform X4

  26. XM_054327296.1XP_054183271.1  BCL-6 corepressor isoform X1

    UniProtKB/Swiss-Prot
    D3DWB3, D3DWB4, Q29RF6, Q6P4B6, Q6W2J9, Q7Z2K7, Q8TEB4, Q96DB3, Q9H232, Q9H233, Q9HCJ7, Q9NXF2
  27. XM_054327325.1XP_054183300.1  BCL-6 corepressor isoform X4

  28. XM_054327313.1XP_054183288.1  BCL-6 corepressor isoform X2

    UniProtKB/TrEMBL
    H7C231
  29. XM_054327318.1XP_054183293.1  BCL-6 corepressor isoform X3

  30. XM_054327322.1XP_054183297.1  BCL-6 corepressor isoform X3

  31. XM_054327332.1XP_054183307.1  BCL-6 corepressor isoform X4

  32. XM_054327303.1XP_054183278.1  BCL-6 corepressor isoform X1

    UniProtKB/Swiss-Prot
    D3DWB3, D3DWB4, Q29RF6, Q6P4B6, Q6W2J9, Q7Z2K7, Q8TEB4, Q96DB3, Q9H232, Q9H233, Q9HCJ7, Q9NXF2
  33. XM_054327307.1XP_054183282.1  BCL-6 corepressor isoform X2

    UniProtKB/TrEMBL
    H7C231
  34. XM_054327324.1XP_054183299.1  BCL-6 corepressor isoform X4

  35. XM_054327304.1XP_054183279.1  BCL-6 corepressor isoform X2

    UniProtKB/TrEMBL
    H7C231
  36. XM_054327335.1XP_054183310.1  BCL-6 corepressor isoform X5

    UniProtKB/TrEMBL
    H7BZ37
  37. XM_054327323.1XP_054183298.1  BCL-6 corepressor isoform X3

  38. XM_054327298.1XP_054183273.1  BCL-6 corepressor isoform X1

    UniProtKB/Swiss-Prot
    D3DWB3, D3DWB4, Q29RF6, Q6P4B6, Q6W2J9, Q7Z2K7, Q8TEB4, Q96DB3, Q9H232, Q9H233, Q9HCJ7, Q9NXF2
  39. XM_054327328.1XP_054183303.1  BCL-6 corepressor isoform X4

  40. XM_054327310.1XP_054183285.1  BCL-6 corepressor isoform X2

    UniProtKB/TrEMBL
    H7C231
  41. XM_054327316.1XP_054183291.1  BCL-6 corepressor isoform X3

  42. XM_054327329.1XP_054183304.1  BCL-6 corepressor isoform X4

  43. XM_054327302.1XP_054183277.1  BCL-6 corepressor isoform X1

    UniProtKB/Swiss-Prot
    D3DWB3, D3DWB4, Q29RF6, Q6P4B6, Q6W2J9, Q7Z2K7, Q8TEB4, Q96DB3, Q9H232, Q9H233, Q9HCJ7, Q9NXF2

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001130139.1: Suppressed sequence

    Description
    NM_001130139.1: This RefSeq was temporarily suppressed because currently there is not sufficient data to support this transcript.
  2. NM_020926.2: Suppressed sequence

    Description
    NM_020926.2: This RefSeq was permanently suppressed because currently there is insufficient support for the transcript and the protein.