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kif5aa - kinesin family member 5A, a

Predicted to enable ATP hydrolysis activity; microtubule binding activity; and plus-end-directed microtubule motor activity. Acts upstream of or within axonal transport of mitochondrion and neuron projection maintenance. Predicted to be part of kinesin complex. Predicted to be active in microtubule. Is expressed in gonad; nervous system; neural tube; and trigeminal placode. Human ortholog(s) of this gene implicated in amyotrophic lateral sclerosis; hereditary spastic paraplegia 10; multiple sclerosis; prostate cancer; and rheumatoid arthritis. Orthologous to human KIF5A (kinesin family member 5A). [provided by Alliance of Genome Resources, Apr 2022]

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Species Gene Architecture aa