U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

CG41378 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 5740475, updated on 2-Nov-2024

Summary

Go to the top of the page Help
Official Symbol
CG41378provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0085638
Locus tag
Dmel_CG41378
See related
AllianceGenome:FB:FBgn0085638
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG41378
Summary
Predicted to enable oxidoreductase activity. Is expressed in adult head. Orthologous to human IFI30 (IFI30 lysosomal thiol reductase). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See CG41378 in Genome Data Viewer
Location:
41A1-41A1; 2-55 cM
Exon count:
4
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (2770380..2846708, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2RHet NW_001848856.1 (1545386..1621674, complement)

Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene pseudo Neighboring gene Major Facilitator Superfamily Transporter 17 Neighboring gene mir-2279 stem loop Neighboring gene long non-coding RNA:CR46481 Neighboring gene Sarcoplasmic calcium-binding protein 1

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Adaptation of gene loci to heterochromatin in the course of Drosophila evolution is associated with insulator proteins. Funikov SY, et al. Sci Rep, 2020 Jul 17. PMID 32681087, Free PMC Article
  2. Comparative Genomic Analyses Provide New Insights into the Evolutionary Dynamics of Heterochromatin in Drosophila. Caizzi R, et al. PLoS Genet, 2016 Aug. PMID 27513559, Free PMC Article
  3. Functional relevance of genes predicted to be affected by epigenetic alterations in atypical teratoid/rhabdoid tumors. Tegeder I, et al. J Neurooncol, 2019 Jan. PMID 30446899
  4. High-fidelity promoter profiling reveals widespread alternative promoter usage and transposon-driven developmental gene expression. Batut P, et al. Genome Res, 2013 Jan. PMID 22936248, Free PMC Article
  5. Landscape and evolution of tissue-specific alternative polyadenylation across Drosophila species. Sanfilippo P, et al. Genome Biol, 2017 Nov 30. PMID 29191225, Free PMC Article

See all (18) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Homology

mobile_element

  • Loc: c2832248-2831084 mobile_element_type = transposon:1360{}6342
  • Loc: c2843140-2842020 mobile_element_type = transposon:1360{}6343

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables oxidoreductase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor IEA
Inferred from Electronic Annotation
more info
  

General protein information

Go to the top of the page Help
Preferred Names
uncharacterized protein
Names
CG41378-PB
CG41378-PC
CG41378-PD
CG41378-PE
NP_001104369.2
NP_001163836.1
NP_001163837.1
NP_001263159.1

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033778.4 Reference assembly

    Range
    2770380..2846708 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001276230.1 → NP_001263159.1  uncharacterized protein Dmel_CG41378, isoform E [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001263159.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A0C4DHN6, C6SUY5
    Conserved Domains (1) summary
    pfam03227
    Location:47 → 124
    GILT; Gamma interferon inducible lysosomal thiol reductase (GILT)

  2. NM_001170366.2 → NP_001163837.1  uncharacterized protein Dmel_CG41378, isoform D [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001163837.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A0C4DHN1, C6SUY5
    Conserved Domains (1) summary
    pfam03227
    Location:24 → 129
    GILT; Gamma interferon inducible lysosomal thiol reductase (GILT)

  3. NM_001110899.3 → NP_001104369.2  uncharacterized protein Dmel_CG41378, isoform C [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001104369.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A0C4DHM7, C6SUY5
    Conserved Domains (1) summary
    pfam03227
    Location:15 → 120
    GILT; Gamma interferon inducible lysosomal thiol reductase (GILT)

  4. NM_001170365.2 → NP_001163836.1  uncharacterized protein Dmel_CG41378, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001163836.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A0C4DHN2, C6SUY5
    Conserved Domains (1) summary
    pfam03227
    Location:47 → 152
    GILT; Gamma interferon inducible lysosomal thiol reductase (GILT)
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
A0A0C4DHM7 A0A0C4DHM7
A0A0C4DHN1 A0A0C4DHN1
A0A0C4DHN2 A0A0C4DHN2
A0A0C4DHN6 A0A0C4DHN6

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Other Literature Sources
Molecular Biology Databases
Research Materials
Tools