U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

KIAA1210 KIAA1210 [ Homo sapiens (human) ]

Gene ID: 57481, updated on 8-Mar-2024

Summary

Go to the top of the page Help
Official Symbol
KIAA1210provided by HGNC
Official Full Name
KIAA1210provided by HGNC
Primary source
HGNC:HGNC:29218
See related
Ensembl:ENSG00000250423 MIM:300995; AllianceGenome:HGNC:29218
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
Predicted to be located in acrosomal vesicle. Predicted to colocalize with basal ectoplasmic specialization. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Restricted expression toward testis (RPKM 25.1) See more
Orthologs
mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
Location:
Xq24
Exon count:
16
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) X NC_000023.11 (119078635..119151130, complement)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) X NC_060947.1 (117456370..117528854, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) X NC_000023.10 (118212598..118284542, complement)

Chromosome X - NC_000023.11Genomic Context describing neighboring genes Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chrX:118125886-118127085 Neighboring gene LON peptidase N-terminal domain and ring finger 3 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 20952 Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chrX:118174593-118175792 Neighboring gene cancer/testis antigen family 47 member C1 Neighboring gene ARL5A pseudogene 1 Neighboring gene NUDT19 pseudogene 1

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help
  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Novel localizations and interactions of intercellular bridge proteins revealed by proteomic profiling†. Iwamori T, et al. Biol Reprod, 2020 Apr 24. PMID 31995159
  2. Identification of KIAA1210 as a novel X-chromosome-linked protein that localizes to the acrosome and associates with the ectoplasmic specialization in testes. Iwamori T, et al. Biol Reprod, 2017 Feb 1. PMID 28203736, Free PMC Article
  3. Prediction of the coding sequences of unidentified human genes. XV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. Nagase T, et al. DNA Res, 1999 Oct 29. PMID 10574462
  4. Discovery of a Human Testis-specific Protein Complex TEX101-DPEP3 and Selection of Its Disrupting Antibodies. Schiza C, et al. Mol Cell Proteomics, 2018 Dec. PMID 30097533, Free PMC Article
  5. The DNA sequence of the human X chromosome. Ross MT, et al. Nature, 2005 Mar 17. PMID 15772651, Free PMC Article

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

Phenotypes

Go to the top of the page Help

Find tests for this gene in the NIH Genetic Testing Registry (GTR)

Review eQTL and phenotype association data in this region using PheGenI

Variation

Go to the top of the page Help

See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Genotypes

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by GOA

Component Evidence Code Pubs
located_in acrosomal vesicle ISS
Inferred from Sequence or Structural Similarity
more info
  
colocalizes_with basal ectoplasmic specialization ISS
Inferred from Sequence or Structural Similarity
more info
  

General protein information

Go to the top of the page Help
Preferred Names
acrosomal protein KIAA1210

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001394962.1 → NP_001381891.1  acrosomal protein KIAA1210 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AL590376, AL772284
    Consensus CDS
    CCDS94659.1
    UniProtKB/TrEMBL
    A0A8I5KWH9
    Related
    ENSP00000510348.1, ENST00000691062.1
    Conserved Domains (1) summary
    pfam15262
    Location:177 → 278
    DUF4592; Domain of unknown function (DUF4592)

  2. NM_020721.1 → NP_065772.1  acrosomal protein KIAA1210 isoform 2

    See identical proteins and their annotated locations for NP_065772.1

    Status: VALIDATED

    Source sequence(s)
    AL441887, AL590376, AL772284, BX099098, DT932686, DV080213
    Consensus CDS
    CCDS48156.1
    UniProtKB/Swiss-Prot
    B7ZCI8, Q5JPN4, Q9ULL0
    Related
    ENSP00000384670.2, ENST00000402510.2
    Conserved Domains (1) summary
    pfam15262
    Location:317 → 418
    DUF4592; Domain of unknown function (DUF4592)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000023.11 Reference GRCh38.p14 Primary Assembly

    Range
    119078635..119151130 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017029689.3 → XP_016885178.1  acrosomal protein KIAA1210 isoform X2

  2. XM_017029688.3 → XP_016885177.1  acrosomal protein KIAA1210 isoform X1

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060947.1 Alternate T2T-CHM13v2.0

    Range
    117456370..117528854 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054327443.1 → XP_054183418.1  acrosomal protein KIAA1210 isoform X2

  2. XM_054327442.1 → XP_054183417.1  acrosomal protein KIAA1210 isoform X1

Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9ULL0.3 GenPept UniProtKB/Swiss-Prot:Q9ULL0

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Chemical Information
Molecular Biology Databases
Research Materials
Tools
Miscellaneous